Abstract: Disclosed is a medical device exhibiting superior lubricating property and durability (lubrication retaining property), the medical device comprising a substrate layer, an adhesive layer formed on at least a portion of the substrate layer, comprising a hydrophilic copolymer comprising a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group, sulfuric acid group, sulfurous acid group, and salts thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group, and a surface lubricious layer formed on at least a portion of the adhesive layer, comprising a hydrophilic polymer dissolvable in a solvent capable of dissolving or swelling the hydrophilic copolymer.

Abstract: A hydrophilic copolymer that can form a surface lubricious layer exhibiting superior lubricating property and durability (lubrication retaining property), is provided. A hydrophilic copolymer having a good solvent solubility is provided. A hydrophilic copolymer is provided containing: structural units derived from a polymerizable monomer (A) having a sulfobetaine structure; structural units derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and groups of salts thereof; and structural units derived from a polymerizable monomer (C) having a photoreactive group.

Abstract: A medical device includes: a substrate layer; an adhesive layer formed on at least a part of the substrate layer and containing a hydrophilic copolymer (1) containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group; and a surface lubricious layer formed on at least a part of the adhesive layer and containing a polymer containing a structural unit derived from acrylamide and a hydrophilic copolymer (2).

Abstract: A medical device includes: a substrate layer; an adhesive layer on at least a part of the substrate layer and containing a hydrophilic copolymer (1) containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group; and a surface lubricious layer formed on at least a part of the adhesive layer and containing a hyaluronic acid or a salt thereof and a hydrophilic copolymer (2).

Abstract: A medical device that exhibits an excellent lubricating property includes: a substrate layer; and a surface lubricious layer formed on at least a part of the substrate layer, and containing a hydroxy group-containing compound selected from a group consisting of a non-volatile alcohol, a partially esterified product thereof, and a partially etherified product thereof, and soluble in water, and a hydrophilic copolymer containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from a group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group.

Abstract: The disclosure provides a medical device that exhibits an excellent lubricating property. The medical device includes: a substrate layer; and a surface lubricious layer formed on at least a part of the substrate layer and containing a hyaluronic acid or a salt thereof and a hydrophilic copolymer containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group.

Abstract: medical device that exhibits an excellent lubricating property includes: a substrate layer; and a surface lubricious layer formed on at least a part of the substrate layer, with the surface lubricious layer containing a polymer containing a structural unit derived from acrylamide, and the surface lubricious layer containing a hydrophilic copolymer containing a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from a group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and salt groups thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group.

Abstract: Disclosed is a hydrophilic copolymer including more than 50% by mol of a structural unit derived from a polymerizable monomer (A) from which a homopolymer having a lower critical solution temperature (LCST) is formed, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (?SO3H), a sulfate group (?OSO3H), a sulfurous acid group (?OSO2H), and a group of salts thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group. Also disclosed is a medical device including the hydrophilic copolymer. The medical device exhibits high sliding property until it reaches a target lesion, and low sliding property after reaching the target lesion. Methods of making and using the hydrophilic copolymer and medical device are also described.

Abstract: Disclosed is a medical device exhibiting superior lubricating property and durability (lubrication retaining property), the medical device comprising a substrate layer, an adhesive layer formed on at least a portion of the substrate layer, comprising a hydrophilic copolymer comprising a structural unit derived from a polymerizable monomer (A) having a sulfobetaine structure, a structural unit derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group, sulfuric acid group, sulfurous acid group, and salts thereof, and a structural unit derived from a polymerizable monomer (C) having a photoreactive group, and a surface lubricious layer formed on at least a portion of the adhesive layer, comprising a hydrophilic polymer dissolvable in a solvent capable of dissolving or swelling the hydrophilic copolymer.

Abstract: A hydrophilic copolymer that can form a surface lubricious layer exhibiting superior lubricating property and durability (lubrication retaining property), is provided. A hydrophilic copolymer having a good solvent solubility is provided. A hydrophilic copolymer is provided containing: structural units derived from a polymerizable monomer (A) having a sulfobetaine structure; structural units derived from a polymerizable monomer (B) having at least one group selected from the group consisting of a sulfonic acid group (—SO3H), a sulfuric acid group (—OSO3H), a sulfurous acid group (—OSO2H), and groups of salts thereof; and structural units derived from a polymerizable monomer (C) having a photoreactive group.

Abstract: A clock spring connector including a fixed member, a movable member rotatably connected to the fixed member, and a rotary plate fixedly connected to the movable member and rotatably mounted on the fixed member. The movable member includes a ceiling plate and a bottom plate connected together by an outer cylindrical portion, both the ceiling member and the movable member defining central openings. The movable member is received in the central openings such that an annular space is defined between an outer surface of the movable member and the outer cylindrical portion. A flexible cable is accommodated in the annular space and includes a first end and a second end. The first end of the flexible cable is connected to the movable member and to a support section of the rotary plate, the support section being located further from the center of rotation of the movable member than the edges of the central openings of the ceiling and bottom walls.

Abstract: A clock spring connector has a fixed body; a movable body rotatably installed on the fixed body; a flexible cable wound between these fixed body and the movable body; and a lock member provided for restricting mutual rotation between the fixed body and the movable body. The clock spring connector further has an engaging portion provided on one of the fixed body and the movable body; a supporting portion having a key groove on the other of the fixed body and the movable body; and the lock member being provided with an engagement portion capable of engaging with the engaging portion and disengaging therefrom and a key capable of entering into the key groove and engaging with the supporting portion by being turned.

Abstract: The present invention relates to a clock spring used for the steering system of an automobile or the like in which a flexible cable is utilized to make an electrical connection between a fixed member and a movable member. The clock spring includes a stationary housing; a rotor rotatably mounted to the stationary housing; the flexible cable wound in a cable accommodating portion defined between the stationary housing and the rotor; and a cover fixed to the stationary housing so as to cover the opened end of the cable accommodating portion. The improvement of this invention resides in a construction by which ribs are provided in the cable accommodating portion to restrict the flexible cable to a position more in the inner periphery of the rotor than in the outer periphery of the same.

Abstract: A harness protecting device of a steering column having a telescopic function includes a protector, having a cable penetrating section in the front and the rear, equipped so as to contract and expand at will across the fixing and moving sides of the steering column having the telescopic function. A pair of flexible bow-like holders in the protector, for dividing a plurality of single core cables from the penetrating section, into two in the width direction of the protector in order to retain the cables. The cables, which are connected to electrical equipment attached to the moving side of the steering column, and which are wired along the steering column, are wired along the bow-like holders in the protector so as to contract and expand.