Patents by Inventor Masanori Miyanishi

Masanori Miyanishi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN LONG-TERM HEMATOPOIETIC STEM CELL MARKER
    Publication number: 20230279354
    Abstract: The present disclosure relates to a marker for enriching or isolating hematopoietic stem cells and a method for using the same, cells or a cell population isolated or enriched by the marker, a method for using the cells or cell population, a drug containing the cells or cell population, and a classifier obtained using the cells or cell population.
    Type: Application
    Filed: July 1, 2021
    Publication date: September 7, 2023
    Applicant: NEXTGEM INC.
    Inventors: Masanori MIYANISHI, Isao MIYATSUKA, My An LE
  • Method for Culturing Hematopoietic Stem Cells
    Publication number: 20230094952
    Abstract: An object of the present invention is to provide a method for culturing one or more hematopoietic stem cells applicable to hematopoietic stem cell transplantation, and a method for producing such one or more hematopoietic stem cells.
    Type: Application
    Filed: December 25, 2020
    Publication date: March 30, 2023
    Applicants: Sumitomo Pharma Co., Ltd., NextGeM Inc.
    Inventors: Atsushi Nakane, Hidetaka Nagata, Shigehiro Asano, Masanori Miyanishi, Hitoshi Suda, Yusuke Shioda
  • METHOD FOR IDENTIFYING CELL HAVING SPECIFIC BIOLOGICAL CHARACTERISTICS BY CELL CLASSIFICATION PROCESS AND APPLICATION METHOD THEREOF
    Publication number: 20230039070
    Abstract: The present invention relates to a method for identifying a cell (group), a method comprising a cell stratifying process utilizing quantitative physical property data, a method for separating a cell (group) utilizing the cell stratifying process, a method for identifying a molecular marker that identifies a cell (group) utilizing the cell stratifying process, a method for culturing a cell (group) utilizing the cell stratifying process, a program for causing a computer to execute a step of identifying a cell (group) utilizing the cell stratifying process, and a system for analyzing, identifying, or separating a cell (group) utilizing the cell stratifying process.
    Type: Application
    Filed: July 1, 2020
    Publication date: February 9, 2023
    Applicant: NEXTGEM INC.
    Inventors: Masanori MIYANISHI, Masakazu NAKAJIMA, Isao MIYATSUKA, My An Le
  • Long term hematopoietic stem cell specific reporter mouse and uses thereof
    Patent number: 10386361
    Abstract: Hoxb5 identifies long-term hematopoietic stem cells. Expression of Hoxb5 distinguishes between LT-HSCs and non-LT-HSCs, and the marker identifies substantially all LT-HSC in the bone marrow. By utilizing fluorescent proteins under the endogenous expression control of Hoxb5, LT-HSC can be monitored and isolated, including without limitation detection and monitoring of HSC in bone morrow; production of LT-HSC from pluripotent stem cells such as iPS cells; for analysis of early stage LT-HSC; in screening methods for expansion and manipulation of LT-HSC, and the like.
    Type: Grant
    Filed: June 7, 2017
    Date of Patent: August 20, 2019
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: James Y. Chen, Masanori Miyanishi, Irving L. Weissman
  • LONG TERM HEMATOPOIETIC STEM CELL SPECIFIC REPORTER MOUSE AND USES THEREOF
    Publication number: 20170350879
    Abstract: Hoxb5 identifies long-term hematopoietic stem cells. Expression of Hoxb5 distinguishes between LT-HSCs and non-LT-HSCs, and the marker identifies substantially all LT-HSC in the bone marrow. By utilizing fluorescent proteins under the endogenous expression control of Hoxb5, LT-HSC can be monitored and isolated, including without limitation detection and monitoring of HSC in bone morrow; production of LT-HSC from pluripotent stem cells such as iPS cells; for analysis of early stage LT-HSC; in screening methods for expansion and manipulation of LT-HSC, and the like.
    Type: Application
    Filed: June 7, 2017
    Publication date: December 7, 2017
    Inventors: James Y. Chen, Masanori Miyanishi, Irving L. Weissman