Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.

Abstract: A cooling device including at least two cooling members to cool a recording medium passing thereover, a coolant circulation unit to circulate a coolant, and tubing that connects the coolant circulation unit to the cooling members and through which the coolant circulates. Each of the cooling members includes a heat-absorbing surface that directly contacts the recording medium or indirectly contacts the recording medium via a thermal transmission member, an internal channel provided within each of the cooling members through which the coolant circulates, and a channel inlet and outlet formed at downstream and upstream ends of each of the cooling members in a direction of conveyance of the recording medium, respectively. One of an interval and a thermal insulator is provided between the cooling members.

Abstract: In a cooling device that includes a cooling roller that comprises a hollow tubular member and a cooling medium transport unit for transporting a cooling liquid to the inside of the cooling roller and contacts a sheet-like member to cool down the paper, a turbulence generating unit that generates turbulence in a cooling liquid is disposed near an inner wall of the outer tube.

Abstract: A cooling device including at least two cooling members to cool a recording medium passing thereover, a coolant circulation unit to circulate a coolant, and tubing that connects the coolant circulation unit to the cooling members and through which the coolant circulates. Each of the cooling members includes a heat-absorbing surface that directly contacts the recording medium or indirectly contacts the recording medium via a thermal transmission member, an internal channel provided within each of the cooling members through which the coolant circulates, and a channel inlet and outlet formed at downstream and upstream ends of each of the cooling members in a direction of conveyance of the recording medium, respectively. One of an interval and a thermal insulator is provided between the cooling members.

Abstract: A cooling device including at least two cooling members to cool a recording medium passing thereover, a coolant circulation unit to circulate a coolant, and tubing that connects the coolant circulation unit to the cooling members and through which the coolant circulates. Each of the cooling members includes a heat-absorbing surface that directly contacts the recording medium or indirectly contacts the recording medium via a thermal transmission member, an internal channel provided within each of the cooling members through which the coolant circulates, and a channel inlet and outlet formed at downstream and upstream ends of each of the cooling members in a direction of conveyance of the recording medium, respectively. One of an interval and a thermal insulator is provided between the cooling members.

Abstract: A cooling device includes a cooling member including a circulation passage for liquid coolant, and a cooling surface being directly or indirectly made to contact with a recording material being conveyed to cool the recording material. The circulation passage includes multiple passage sections arranged crossing to a conveying direction of the recording material, and a folded passage section to guide the liquid coolant from one of the multiple passage sections to another one of the multiple passage sections while changing a flowing direction of the liquid coolant. The folded passage section is disposed outside of an image forming area of the recording material on the cooling surface of the cooling member.

Abstract: A cooling device includes a heat receiving unit arranged to contact with a cooling target to receive heat of the cooling target; a heat radiating unit configured to radiate heat of coolant; a tank configured to store therein the coolant; a circulating path configured to circulate the coolant through the heat receiving unit, the heat radiating unit, and the tank; a pump configured to transfer the coolant in the circulating path; and a liquid transfer detecting unit configured to detect liquid transfer of the coolant. The liquid transfer detecting unit includes a detector arranged above a liquid level of the coolant stored in the tank at a position where the coolant having flowed into the tank is hit when the coolant is transferred. The detector is arranged so as to be visible from the outside of the tank.

Abstract: Of a cooling device that is for use in an image forming apparatus and that includes: a heat receiving unit that receives heat from a cooling target and that is disposed to come into and away from contact with the cooling target; a heat radiating unit that radiates the heat received by the heat receiving unit; a heat conductive member disposed on at least one of a surface of the heat receiving unit on the side facing the cooling target and a surface of the cooling target on the side facing the heat receiving unit; and a protection member that is disposed on the heat conductive member to protect the heat conductive member, the protection member is substantially incompatible with binder resin of toner for use in the image forming apparatus.

Abstract: A cooling device including at least two cooling members to cool a recording medium passing thereover, a coolant circulation unit to circulate a coolant, and tubing that connects the coolant circulation unit to the cooling members and through which the coolant circulates. Each of the cooling members includes a heat-absorbing surface that directly contacts the recording medium or indirectly contacts the recording medium via a thermal transmission member, an internal channel provided within each of the cooling members through which the coolant circulates, and a channel inlet and outlet formed at downstream and upstream ends of each of the cooling members in a direction of conveyance of the recording medium, respectively. One of an interval and a thermal insulator is provided between the cooling members.

Abstract: A cooling device using a liquid coolant, including a heat receiving part separatably contactable to a target to be cooled detachably installable in an image forming apparatus, a heat releasing part to release heat from the liquid coolant, a circulation channel through which the liquid coolant is circulated between the heat receiving part and the heat releasing part, and a pump operatively connected to the circulation channel to convey the liquid coolant through the circulation channel. The circulation channel has a flexible part and a metal part continuous with the flexible part.

Abstract: A cooling device including at least two cooling members to cool a recording medium passing thereover, a coolant circulation unit to circulate a coolant, and tubing that connects the coolant circulation unit to the cooling members and through which the coolant circulates. Each of the cooling members includes a heat-absorbing surface that directly contacts the recording medium or indirectly contacts the recording medium via a thermal transmission member, an internal channel provided within each of the cooling members through which the coolant circulates, and a channel inlet and outlet formed at downstream and upstream ends of each of the cooling members in a direction of conveyance of the recording medium, respectively. One of an interval and a thermal insulator is provided between the cooling members.

Abstract: A liquid-cooling-type cooling device includes a circulatory path for coolant that cools a temperature rise portion; a heat absorbing unit that absorbs a heat from the temperature rise portion by the coolant; a heat radiating unit that radiate the heat from the coolant; a pump that circulates the coolant; and a plurality of liquid-contacting metal portions that comes into contact with the coolant, each of the liquid-contacting metal portions being made of a metal material. At least one of the liquid-contacting metal portions is grounded.

Abstract: A cooling device to cool an apparatus includes a heat receiver to receive heat from a hot portion of the apparatus using a coolant while contacting the hot portion, a heat releaser to cool the heat-received coolant to release the heat from the hot portion to outside the apparatus, the heat releaser having a variable-speed fan of multiple operation speed modes including an off mode, a coolant circulation system through which the coolant is circulated between the heat receiver and the heat releaser, a variable-speed pump to move the coolant through the coolant circulation system, whose operation speed modes include an off mode and relate to a coolant flow rate of the pump, a temperature sensor to detect a temperature in the hot portion, and a controller to control the operation modes of the fan and the pump in accordance with the temperature detected by the temperature sensor.

Abstract: An image forming apparatus includes an image forming unit that creates an image and a liquid cooling unit. The liquid cooling unit includes a heat receiving disposed in contact with a temperature rising portion, in the image forming unit, in which a temperature rises due to an image forming operation by the image forming unit, a heat radiating unit that radiates heat of a cooling liquid, a flow passage forming member that allows the cooling liquid to circulate between the heat receiving unit and the heat radiating unit, and a conveying unit that conveys the cooling liquid through the flow passage forming member. The heat radiating unit includes a radiator, and the radiator is disposed at a downstream side of the conveying unit in a cooling liquid flow direction and at an upstream side of the heat receiving unit in the cooling liquid flow direction.

Abstract: In a cooling device that includes a cooling roller that comprises a hollow tubular member and a cooling medium transport unit for transporting a cooling liquid to the inside of the cooling roller and contacts a sheet-like member to cool down the paper, a turbulence generating unit that generates turbulence in a cooling liquid is disposed near an inner wall of the outer tube.

Abstract: In a cooling device that includes a cooling roller that comprises a hollow tubular member and a cooling medium transport unit for transporting a cooling liquid to the inside of the cooling roller and contacts a sheet-like member to cool down the paper, a turbulence generating unit that generates turbulence in a cooling liquid is disposed near an inner wall of the outer tube.

Abstract: A cooling device includes a heat receiving unit disposed to contact a surface of a temperature-increasing part the temperature of which increases during an image forming process; a radiation unit transferring heat from a cooling liquid; a tube for circulating the cooling liquid between the heat receiving unit and the radiation unit in a liquid circulation direction; a conveying unit conveying the cooling liquid through the tube; a coupling having an internal flow path and including a first end to which a first part of the tube is connected and a second end to which a second part of the tube is connected; and an outlet for draining the cooling liquid from the tube. At least one of the first part of the tube and the second part of the tube extends to a position lower than the position of the coupling.

Abstract: A cooling device includes a cooling member including a circulation passage for liquid coolant, and a cooling surface being directly or indirectly made to contact with a recording material being conveyed to cool the recording material. The circulation passage includes multiple passage sections arranged crossing to a conveying direction of the recording material, and a folded passage section to guide the liquid coolant from one of the multiple passage sections to another one of the multiple passage sections while changing a flowing direction of the liquid coolant. The folded passage section is disposed outside of an image forming area of the recording material on the cooling surface of the cooling member.

Abstract: Disclosed is a cooling device that includes a cooling part that is movably provided between a first position and a second position different from the first position with respect to an image forming apparatus main body and cools a periphery thereof with a cooling medium to be supplied; a cooling medium supply part that is provided in the image forming apparatus main body and cools and supplies the cooling medium to the cooling part; and a connecting member that connects the cooling part to the cooling medium supply part to circulate the cooling medium between the cooling part and the cooling medium supply part; wherein the connecting member is configured to include a flexible member and spirally provided with a moving direction of the cooling part as an axis center.

Abstract: This invention provides an emulsified composition comprising (A) edible oil material, (B) sucrose diacetate hexaisobutyrate (SAIB), (C) octenylsuccinic acid-modified gum arabic, (D) polyalcohol and (E) water, in which the particles are finer and more uniform than those in conventional emulsions prepared with gum arabic, and which is easy of preparation.