Patents by Inventor Masao Hoshiyama

Masao Hoshiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel benzylalcohol derivatives and processes for preparing the same
    Patent number: 4131686
    Abstract: A compound of the formula: ##STR1## wherein R is lower alkyl, may be prepared, for example, by reducing a compound of the formula: ##STR2## wherein R is same as above. Other methods for preparing the compound [I] are also disclosed. The compound [I] and a pharmaceutically acceptable acid addition salt thereof are useful as anti-diabetic agents.
    Type: Grant
    Filed: December 6, 1976
    Date of Patent: December 26, 1978
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Muneyoshi Ikezaki, Yashushi Okazaki, Nobuo Ito, Masao Hoshiyama, Taku Nagao, Hiromichi Nakajima
  • Novel benzylalcohol derivatives as antidiabetics and cardiotonics
    Patent number: 4072759
    Abstract: A compound having the formula: ##STR1## wherein Ring A is monohydroxyphenyl, or a pharmaceutically acceptable acid addition salt thereof is prepared by catalytic hydrogenation of a compound having the formula: ##STR2## wherein A' is monobenzyloxyphenyl, and Y is carbonyl or hydroxymethylene. The compound (I) in which Ring A is 4-hydroxyphenyl or 3-hydroxyphenyl is useful as a cardiotonic agent. On the other hand, the compound (I) in which Ring A is 2-hydroxyphenyl is useful as an anti-diabetic agent.
    Type: Grant
    Filed: November 10, 1976
    Date of Patent: February 7, 1978
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Muneyoshi Ikezaki, Nobuo Ito, Yasushi Okazaki, Masao Hoshiyama, Taku Nagao, Hiromichi Nakajima
  • Benzylalcohol amine derivatives
    Patent number: 4032575
    Abstract: A compound having the formula: ##STR1## wherein Ring A is monohydroxyphenyl, or a pharmaceutically acceptable acid addition salt thereof is prepared by catalytic hydrogenation of a compound having the formula: ##STR2## wherein A' is monobenzyloxyphenyl, and Y is carbonyl or hydroxymethylene. The compound (I) in which Ring A is 4-hydroxyphenyl or 3-hydroxyphenyl is useful as a cardiotonic agent. On the other hand, the compound (I) in which Ring A is 2-hydroxyphenyl is useful as an anti-diabetic agent.
    Type: Grant
    Filed: October 1, 1975
    Date of Patent: June 28, 1977
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Muneyoshi Ikezaki, Nobuo Ito, Yasushi Okazaki, Masao Hoshiyama, Taku Nagao, Hiromichi Nakajima
  • .alpha.-(3,4-Dimethoxyphenethylaminomethyl)-3,4 or 3,5-dihydroxybenzylalcohols and salts thereof
    Patent number: 3952021
    Abstract: A compound of the formula: ##SPC1##Wherein Ring A' is dibenzyloxyphenyl and Y is carbonyl or hydroxymethylene, is subjected to catalytic hydrogenation. A compound of the formula: ##SPC2##Wherein Ring A is dihydroxyphenyl, is produced. The product is useful as a cardiotonic agent. It is also characterized by the high potency ratio of adrenergic .beta..sub.1 -receptor stimulating activity to adrenergic .beta..sub.2 -receptor stimulating activity.
    Type: Grant
    Filed: April 22, 1974
    Date of Patent: April 20, 1976
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Muneyoshi Ikezaki, Yasushi Okazaki, Nobuo Ito, Taku Nagao, Masao Hoshiyama, Hiromichi Nakajima