Patents by Inventor Masao Tsukazaki

Masao Tsukazaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Process for the Preparation of Hexacyclic Compounds
    Publication number: 20090326225
    Abstract: This invention relates to novel processes for the preparation of compounds of the formula [1], wherein R1, R2, R3 and R4 are as defined in the claims and description as well as pharmaceutically acceptable salts thereof. The compounds of the formula [1] are hexacyclic compounds having potent anti-tumor activity.
    Type: Application
    Filed: August 25, 2009
    Publication date: December 31, 2009
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hiroshi Fukuda, Takeshi Murata, Satoshi Niizuma, Hitomi Suda, Masao Tsukazaki
  • Novel Process for the Preparation of Hexacyclic Compounds
    Publication number: 20090312554
    Abstract: This invention relates to novel processes for the preparation of compounds of the formula [1], wherein R1, R2, R3 and R4 are as defined in the claims and description as well as pharmaceutically acceptable salts thereof. The compounds of the formula [1] are hexacyclic compounds having potent anti-tumor activity.
    Type: Application
    Filed: August 25, 2009
    Publication date: December 17, 2009
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: HIROSHI FUKUDA, TAKESHI MURATA, SATOSHI NIIZUMA, HITOMI SUDA, MASAO TSUKAZAKI
  • Process for the preparation of hexacyclic compounds
    Patent number: 7595400
    Abstract: This invention relates to novel processes for the preparation of compounds of the formula [1], wherein R1, R2, R3 and R4 are as defined in the claims and description as well as pharmaceutically acceptable salts thereof. The compounds of the formula [1] are hexacyclic compounds having potent anti-tumor activity.
    Type: Grant
    Filed: February 20, 2004
    Date of Patent: September 29, 2009
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hiroshi Fukuda, Takeshi Murata, Satoshi Niizuma, Hitomi Suda, Masao Tsukazaki
  • N-substituted carbamoyloxyalkyl-azolium derivatives
    Patent number: 7459561
    Abstract: N-substituted carbamoyloxyalkyl-azolium derivatives which have antifungal activity and are useful for the treatment of fungal diseases.
    Type: Grant
    Filed: August 15, 2006
    Date of Patent: December 2, 2008
    Assignee: Basilea Pharmaceutica AG
    Inventors: Hiroshi Fukuda, Tadakatsu Hayase, Eisaku Mizuguchi, Nobuo Shimma, Jun Ohwada, Nobuhiro Oikawa, Masahiro Sakaitani, Masao Tsukazaki, Isao Umeda
  • N-phenyl substituted carbamoyloxyalkyl-azolium derivatives
    Patent number: 7189858
    Abstract: N-substituted carbamoyloxyalkyl-azolium derivatives Which have antifungal activity and are useful for the treatment of fungal diseases.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: March 13, 2007
    Assignee: Basilea Pharmaceutica AG
    Inventors: Hiroshi Fukuda, Tadakatsu Hayase, Eisaku Mizuguchi, Nobuo Shimma, Jun Ohwada, Nobuhiro Oikawa, Masahiro Sakaitani, Masao Tsukazaki, Isao Umeda
  • N-substituted carbamoyloxyalkyl-azolium derivatives
    Publication number: 20070027322
    Abstract: N-substituted carbamoyloxyalkyl-azolium derivatives which have antifungal activity and are useful for the treatment of fungal diseases.
    Type: Application
    Filed: August 15, 2006
    Publication date: February 1, 2007
    Inventors: Hiroshi Fukuda, Tadakatsu Hayase, Eisaku Mizuguchi, Nobuo Shimma, Jun Ohwada, Nobuhiro Oikawa, Masahiro Sakaitani, Masao Tsukazaki, Isao Umeda
  • Intermediates for N-substituted carbamoyloxyalkyl-azolium derivatives
    Patent number: 7151182
    Abstract: N-substituted carbamoyloxyalkyl-azolium derivatives which have antifungal activity and are useful for the treatment of fungal diseases.
    Type: Grant
    Filed: September 3, 2004
    Date of Patent: December 19, 2006
    Assignee: Basilea Pharmaceutica AG
    Inventors: Hiroshi Fukuda, Tadakatsu Hayase, Eisaku Mizuguchi, Nobuo Shimma, Jun Ohwada, Nobuhiro Oikawa, Masahiro Sakaitani, Masao Tsukazaki, Isao Umeda
  • Hexacyclic compounds and their therapeutic use
    Patent number: 7109195
    Abstract: The present invention relates to hexacyclic compound of the formula [1], wherein Z, R3 and R4 are as identified therein, and pharmaceutically acceptable salts thereof. These compounds are useful in the treatment of cell proliferative disorders.
    Type: Grant
    Filed: September 16, 2004
    Date of Patent: September 19, 2006
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Takeshi Murata, Satoshi Niizuma, Nobuo Shimma, Hitomi Suda, Masao Tsukazaki
  • Novel hexacyclic compounds
    Publication number: 20050059679
    Abstract: The present invention relates to hexacyclic compound of the formula [1], wherein Z, R3 and R4 are as identified therein, and pharmaceutically acceptable salts thereof. These compounds are useful in the treatment of cell proliferative disorders.
    Type: Application
    Filed: September 16, 2004
    Publication date: March 17, 2005
    Inventors: Takeshi Murata, Satoshi Niizuma, Nobuo Shimma, Hitomi Suda, Masao Tsukazaki
  • Intermediates for N-substituted carbamoyloxyalkyl-azolium derivatives
    Publication number: 20050038075
    Abstract: N-substituted carbamoyloxyalkyl-azolium derivatives which have antifungal activity and are useful for the treatment of fungal diseases.
    Type: Application
    Filed: September 3, 2004
    Publication date: February 17, 2005
    Inventors: Hiroshi Fukuda, Tadakatsu Hayase, Eisaku Mizuguchi, Nobuo Shimma, Jun Ohwada, Nobuhiro Oikawa, Masahiro Sakaitani, Masao Tsukazaki, Isao Umeda
  • N-phenyl substituted carbamoyloxyalkyl-azolium derivatives
    Publication number: 20050038038
    Abstract: N-substituted carbamoyloxyalkyl-azolium derivatives Which have antifungal activity and are useful for the treatment of fungal diseases.
    Type: Application
    Filed: September 3, 2004
    Publication date: February 17, 2005
    Inventors: Hiroshi Fukuda, Tadakatsu Hayase, Eisaku Mizuguchi, Nobuo Shimma, Jun Ohwada, Nobuhiro Oikawa, Masahiro Sakaitani, Masao Tsukazaki, Isao Umeda
  • Hexacyclic compounds
    Patent number: 6825194
    Abstract: The present invention relates to hexacyclic compound of the formula [1], wherein Z, R3 and R4 are as identified therein, and pharmaceutically acceptable salts thereof. These compounds are useful in the treatment of cell proliferative disorders.
    Type: Grant
    Filed: November 26, 2002
    Date of Patent: November 30, 2004
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Takeshi Murata, Satoshi Niizuma, Nobuo Shimma, Hitomi Suda, Masao Tsukazaki
  • N-substituted carbamoyloxyalkyl-azolium derivatives
    Patent number: 6812238
    Abstract: N-substituted carbamoyloxyalkyl-azolium derivatives which have antifungal activity and are useful for the treatment of fungal diseases.
    Type: Grant
    Filed: October 31, 2000
    Date of Patent: November 2, 2004
    Assignee: Basilea Pharmaceutica AG
    Inventors: Hiroshi Fukuda, Tadakatsu Hayase, Eisaku Mizuguchi, Nobuo Shimma, Jun Ohwada, Nobuhiro Oikawa, Masahiro Sakaitani, Masao Tsukazaki, Isao Umeda
  • Novel hexacyclic compounds
    Publication number: 20030144304
    Abstract: The present invention relates to hexacyclic compound of the formula [1], 1
    Type: Application
    Filed: November 26, 2002
    Publication date: July 31, 2003
    Inventors: Takeshi Murata, Satoshi Niizuma, Nobuo Shimma, Hitomi Suda, Masao Tsukazaki
  • Azoles for treatment of fungal infections
    Patent number: 6300353
    Abstract: Azole derivatives of the formula I wherein R14, R15 are each independently hydrogen or fluorine, T is a group of the formula: wherein R9 is pyrrolidinyl or a group A—NH—B—, A is hydrogen or straight-chain or branched C1-C5 alkyl; B is straight-chain or branched C1-C4 alkylene, —CH2—CONH—CH2 or —CH2CH2CH2—CH(NH2); and X− is a pharmaceutically acceptable anion; and pharmaceutically acceptable salts of said compounds, and hydrates and solvates of the compounds of formula I and the salts thereof can be used in the production of medicaments for treating fungal infections and mycoses.
    Type: Grant
    Filed: March 5, 1999
    Date of Patent: October 9, 2001
    Assignee: Basilea Pharmaceutica AG, a Swiss Company
    Inventors: Tadakatsu Hayase, Shigeyasu Ichihara, Yoshiaki Isshiki, Pingli Liu, Jun Ohwada, Toshiya Sakai, Nobuo Shimma, Masao Tsukazaki, Isao Umeda, Toshikazu Yamazaki