Patents by Inventor Masaoki Goto
Masaoki Goto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11786480Abstract: The present invention provides a transdermal absorption preparation in which a drug-containing adhesive layer is formed on a support, the aforementioned adhesive layer contains at least a thermoplastic elastomer and a higher fatty acid ester, and a content of a tackifier is not more than 10 wt %, which is superior in drug solubility and releasability, as well as adhesiveness to the skin and low irritation to the skin.Type: GrantFiled: December 9, 2016Date of Patent: October 17, 2023Assignee: KM TRANSDERM LTD.Inventors: Atsuyo Hamada, Masaoki Goto
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Publication number: 20230310339Abstract: A patch includes an adhesive laver, where the adhesive layer includes (a) 3-[(3R*,4R*)-3-(dimethylamionomethyl)tetrahydropyran-4-yl]phenol and (b) at least one selected from the group consisting of organic acids, amides, and alcohols, and an amount of the (b) is 50 parts by mass or greater relative to 100 parts mass of the (a). A production method of patch includes forming an adhesive layer with a mixture, where the mixture is obtained by mixing (a) 3-[(3R*,4R*)-3-(dimethylamionomethyl)tetrahydropyran-4-yl]phenol, and (b) a polar functional group-containing organic compound at 80° C. or lower.Type: ApplicationFiled: August 19, 2021Publication date: October 5, 2023Inventors: Masaya MIZUTANI, Hiroyuki OGINO, Masaoki GOTO
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Publication number: 20230201131Abstract: A percutaneous absorption preparation for the treatment of dementia wherein the drug-containing layer contains donepezil or a pharmaceutically acceptable salt thereof as an active ingredient and a stabilizer that is either (i) a mixture of a thiocyanate salt and a compound selected from the group consisting of tea catechin, (+)-catechin, epigallocatechin gallate, ascorbic acid, and isoascorbic acid, or (ii) a mixture of monothioglycerol and a compound selected from the group consisting of tea catechin, (+)-catechin, epigallocatechin gallate, and ascorbic acid is disclosed. The percutaneous absorption preparation meets the criteria of Procedure 1 and Procedure 2 of the U.S. Pharmacopoeia in short-term stress test (70° C. 48 hours storage), long-term accelerated test 1 (40° C. relative humidity 75% 1 month storage), and long-term accelerated test 2 (40° C. relative humidity 75% 3 months storage), and exhibits improved stability for long-term preservation.Type: ApplicationFiled: May 12, 2021Publication date: June 29, 2023Applicants: DONG-A ST CO., LTD., KM TRANSDERM LTD.Inventors: Sun-Woo JANG, Chang-Yell SHIN, Hae-Sun KIM, Kwang-Ho CHA, Hyun-jung KIM, Sang-Min HYUN, Masaoki GOTO
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Publication number: 20230149322Abstract: A patch includes: a support; and an adhesive layer on the support. The adhesive layer includes blonanserin or a salt thereof, a thermoplastic elastomer, and a higher fatty acid ester.Type: ApplicationFiled: April 26, 2021Publication date: May 18, 2023Inventors: Hiroyuki OGINO, Atsuki MATSUO, Masaoki GOTO
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Publication number: 20220258374Abstract: A tool set for manufacturing adhesive patches, by processing laminate web. The tool set includes a cutting tool having a cutting face lying in a cutting plane, and an embossing tool having a pressing face lying in a pressing plane, where the cutting plane and the pressing plane are parallel. The embossing tool is configured to press an edge area shape of the adhesive patch to be manufactured, and the cutting tool is configured to cut out the adhesive patch to be manufactured by cutting in edge area or outside the edge area. Furthermore, a method of manufacturing adhesive patches. The method essentially includes a feeding step, a pressing step and cutting step. Lastly an adhesive layering having a backing layer and an adhesive matrix layer. The backing layer having a larger size than the adhesive matrix layer.Type: ApplicationFiled: May 26, 2020Publication date: August 18, 2022Inventors: Markus Bee, Helena Gallinger, Alexander Saifert, Andreas Weber-Stebliwez, Georg Schlögel, Akio Nishiura, Akinori Sasaki, Masaoki Goto
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Publication number: 20220047524Abstract: A percutaneous absorption preparation including donepezil for the treatment of dementia is disclosed. The percutaneous absorption preparation for the treatment of dementia includes a support layer, a drug-containing layer, and a release layer, wherein the drug-containing layer contains donepezil or a pharmaceutically acceptable salt thereof as an active ingredient; monothioglycerol, thiocyanate metal salt (preferably potassium salt) or dimethylthiourea as a stabilizer; and a pressure-sensitive adhesive. Also disclosed is a percutaneous absorption preparation for the treatment of dementia with reduced the formation of donepezil impurities.Type: ApplicationFiled: September 5, 2019Publication date: February 17, 2022Applicants: DONG-A ST CO., LTD, KM TRANSDERM LTD.Inventors: Sun-Woo JANG, Chang-Yell SHIN, Hae-Sun KIM, Kwang-Ho CHA, Hyun-Jung KIM, Masaoki GOTO
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Publication number: 20220040121Abstract: The objective of the present invention is to provide a local anesthetic agent-containing patch having a skin permeability, cohesion force and adhesive property practical as a pharmaceutical product. The patch of the present invention is characterized in comprising a backing layer, and an adhesive layer on the backing layer, wherein the adhesive layer comprises at least a local anesthetic agent, a thermoplastic elastomer, a higher fatty acid ester, and a polyol fatty acid monoester, and a ratio of the higher fatty acid ester to 100 mass parts of the thermoplastic elastomer is 25 mass parts or more and 200 mass parts or less.Type: ApplicationFiled: February 27, 2020Publication date: February 10, 2022Applicant: KANEKA CORPORATIONInventors: Hiroyuki OGINO, Mitsuji AKAZAWA, Masaoki GOTO
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Publication number: 20210059956Abstract: A percutaneous absorption preparation is disclosed. The percutaneous absorption preparation contains donepezil for treatment of dementia, wherein the preparation includes: (a) donepezil or its pharmaceutically acceptable salt as active component, (b) propylene glycol monocaprylate as solubilizer, and (c) styrene-isoprene-styrene block copolymer (“SIS”) as adhesive. The percutaneous absorption preparation has low skin irritation and high skin penetration.Type: ApplicationFiled: November 7, 2018Publication date: March 4, 2021Applicants: DONG-A ST CO., LTD., KM TRANSDERM LTD.Inventors: Sun-Woo JANG, Chang-Yell SHIN, Jeong-Soo KIM, Hae-Sun KIM, Kwang-Ho CHA, Hyun-Jung KIM, Masaoki GOTO
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Patent number: 10758494Abstract: The present invention provides a patch containing an adhesive layer maintaining a drug, which is formed on a support, wherein the aforementioned adhesive layer comprises a thermoplastic elastomer, a non-volatile hydrocarbon oil in an amount exceeding 50 parts by weight and not more than 800 parts by weight per 100 parts by weight of the elastomer, and rivastigmine or a salt thereof, and the aforementioned adhesive layer optionally further contains a tackifier at a content in the adhesive layer of not more than 10 wt %.Type: GrantFiled: June 12, 2013Date of Patent: September 1, 2020Assignee: KM Transderm Ltd.Inventors: Hiroyuki Ogino, Masaoki Goto, Atsuyo Hamada, Mitsuji Akazawa, Sadao Yukimoto
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Publication number: 20200214991Abstract: Provided is an adhesive sheet for adhesion to the skin, which has sufficient adhesiveness and causes low skin irritation. The adhesive sheet comprises a support and an adhesive layer formed on the support, in which the adhesive layer contains at least a thermoplastic elastomer and a non-volatile hydrocarbon oil. Further provided is a transdermal absorption preparation having sufficient adhesiveness and drug releaseability and causes low skin irritation. The transdermal absorption preparation comprises an adhesive sheet as described herein and a drug or a pharmaceutically acceptable salt thereof that is contained in the adhesive layer of the sheet.Type: ApplicationFiled: March 16, 2020Publication date: July 9, 2020Applicant: KM Transderm Ltd.Inventors: Hiroyuki OGINO, Sadao YUKIMOTO, Atsuyo HAMADA, Mitsuji AKAZAWA, Masaoki GOTO
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Patent number: 10314791Abstract: The invention provides an adhesive sheet for skin, which shows sufficient adhesiveness to the skin and causes low skin irritation. The adhesive sheet contains an adhesive layer formed on a support, in which the adhesive layer contains at least a thermoplastic elastomer, a non-volatile hydrocarbon oil, and polyisobutylene, but no tackifier. The polyisobutylene is a medium molecular weight polyisobutylene with a viscosity average molecular weight of more than 100,000 and not more than 500,000. The invention also provides a percutaneous absorption preparation containing a drug or a pharmaceutically acceptable salt thereof in an adhesive layer of the inventive adhesive sheet for skin.Type: GrantFiled: December 4, 2015Date of Patent: June 11, 2019Assignee: KM Transderm Ltd.Inventors: Hiroyuki Ogino, Sadao Yukimoto, Atsuyo Hamada, Mitsuji Akazawa, Masaoki Goto
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Publication number: 20190167602Abstract: The present invention provides transdermal absorption preparation having a support, and a drug-containing adhesive layer formed on the support, wherein a drug-containing adhesive layer contains donepezil or a salt thereof, and a higher fatty acid salt.Type: ApplicationFiled: January 24, 2019Publication date: June 6, 2019Applicant: KM Transderm Ltd.Inventors: Atsuyo HAMADA, Mitsuji AKAZAWA, Keiko YAMASAKI, Masaoki GOTO
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Publication number: 20190000774Abstract: The present invention provides a transdermal absorption preparation in which a drug-containing adhesive layer is formed on a support, the aforementioned adhesive layer contains at least a thermoplastic elastomer and a higher fatty acid ester, and a content of a tackifier is not more than 10 wt %, which is superior in drug solubility and releasability, as well as adhesiveness to the skin and low irritation to the skin.Type: ApplicationFiled: December 9, 2016Publication date: January 3, 2019Applicant: KM TRANSDERM LTD.Inventors: Atsuyo HAMADA, Masaoki GOTO
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Transdermal patch with different viscosity hydrocarbon oils in the drug layer and the adhesive layer
Patent number: 9895320Abstract: A patch containing a storage layer retaining a drug or a pharmaceutically acceptable salt thereof and an adhesive layer which are formed on a support, wherein the adhesive layer contains a thermoplastic elastomer, and a non-volatile hydrocarbon oil in more than 50 parts by weight and not more than 800 parts by weight per 100 parts by weight of the elastomer, and the adhesive layer optionally further contains a tackifier at a content of not more than 10 wt %.Type: GrantFiled: September 28, 2013Date of Patent: February 20, 2018Assignee: KM Transderm Ltd.Inventors: Hiroyuki Ogino, Masaoki Goto, Atsuyo Hamada, Mitsuji Akazawa, Sadao Yukimoto -
Publication number: 20170367994Abstract: The present invention provides transdermal absorption preparation having a support, and a drug-containing adhesive layer formed on the support, wherein a drug-containing adhesive layer contains donepezil or a salt thereof, and a higher fatty acid salt.Type: ApplicationFiled: September 11, 2017Publication date: December 28, 2017Applicant: KM Transderm Ltd.Inventors: Atsuyo HAMADA, Mitsuji AKAZAWA, Keiko YAMASAKI, Masaoki GOTO
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Publication number: 20170333367Abstract: The present invention provides an adhesive sheet for skin, which shows sufficient adhesiveness to the skin and causes low skin irritation. The first adhesive sheet for skin of the present invention has an adhesive layer formed on a support, wherein the aforementioned adhesive layer contains at least a thermoplastic elastomer, non-volatile hydrocarbon oil and polyisobutylene having a viscosity average molecular weight of more than 100,000 and not more than 500,000, and does not contain a tackifier.Type: ApplicationFiled: December 4, 2015Publication date: November 23, 2017Applicant: KM Transderm Ltd.Inventors: Hiroyuki OGINO, Sadao YUKIMOTO, Atsuyo HAMADA, Mitsuji AKAZAWA, Masaoki GOTO
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Publication number: 20160250156Abstract: The present invention provides transdermal absorption preparation having a support, and a drug-containing adhesive layer formed on the support, wherein a drug-containing adhesive layer contains donepezil or a salt thereof, and a higher fatty acid salt.Type: ApplicationFiled: May 4, 2016Publication date: September 1, 2016Applicant: KM Transderm Ltd.Inventors: Atsuyo HAMADA, Mitsuji AKAZAWA, Keiko YAMASAKI, Masaoki GOTO
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Publication number: 20160206568Abstract: Provided is an adhesive sheet for adhesion to the skin, which has sufficient adhesiveness and causes low skin irritation. The adhesive sheet comprises a support and an adhesive layer formed on the support, in which the adhesive layer contains at least a thermoplastic elastomer and a non-volatile hydrocarbon oil. Further provided is a transdermal absorption preparation having sufficient adhesiveness and drug releaseability and causes low skin irritation. The transdermal absorption preparation comprises an adhesive sheet as described herein and a drug or a pharmaceutically acceptable salt thereof that is contained in the adhesive layer of the sheet.Type: ApplicationFiled: June 12, 2014Publication date: July 21, 2016Inventors: Hiroyuki OGINO, Sadao YUKIMOTO, Atsuyo HAMADA, Mitsuji AKAZAWA, Masaoki GOTO
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Publication number: 20150374642Abstract: A patch containing a storage layer retaining a drug or a pharmaceutically acceptable salt thereof and an adhesive layer which are formed on a support, wherein the adhesive layer contains a thermoplastic elastomer, and a non-volatile hydrocarbon oil in more than 50 parts by weight and not more than 800 parts by weight per 100 parts by weight of the elastomer, and the adhesive layer optionally further contains a tackifier at a content of not more than 10 wt %.Type: ApplicationFiled: September 28, 2013Publication date: December 31, 2015Inventors: Hiroyuki OGINO, Masaoki GOTO, Atsuyo HAMADA, Mitsuji AKAZAWA, Sadao YUKIMOTO
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Publication number: 20150224063Abstract: The present invention provides a patch containing an adhesive layer maintaining a drug, which is formed on a support, wherein the aforementioned adhesive layer comprises a thermoplastic elastomer, a non-volatile hydrocarbon oil in an amount exceeding 50 parts by weight and not more than 800 parts by weight per 100 parts by weight of the elastomer, and rivastigmine or a salt thereof, and the aforementioned adhesive layer optionally further contains a tackifier at a content in the adhesive layer of not more than 10 wt %.Type: ApplicationFiled: June 12, 2013Publication date: August 13, 2015Inventors: Hiroyuki Ogino, Masaoki Goto, Atsuyo Hamada, Mitsuji Akazawa, Sadao Yukimoto