Patents by Inventor Masaru Nakao
Masaru Nakao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180312730Abstract: A resin composition for sealing of the present invention contains an epoxy resin (A), a curing agent (B), an inorganic filler (C), and a compound (D) represented by Formula (1). In Formula (1), R1 represents a polar group or a hydrocarbon group. An electronic component device (10) of the present invention has an electronic component (11) and a sealing material (12) sealing the electronic component (11), in which the sealing material (12) is a cured substance of the resin composition for sealing.Type: ApplicationFiled: April 30, 2015Publication date: November 1, 2018Applicant: SUMITOMO BAKELITE CO., LTD.Inventors: Masaru NAKAO, Hirofumi KURODA
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Patent number: 4303663Abstract: Butyrophenone compounds having excellent psychotropic activities represented by the formula: ##STR1## wherein R.sup.1 is a halogen atom, R.sup.2 is a lower alkyl group, and Z is a group of either one of the formulae: ##STR2## (wherein the dotted line indicates the optional presence of an additional single bond linkage, R.sup.3 is a hydrogen atom or a hydroxyl group but only when said additional single bond linkage is not present and R.sup.4 is a hydrogen atom or a phenyl or benzyl group optionally substituted with one or two substituents selected from the group consisting of halogen, lower alkyl, lower alkoxy and trifluoromethyl on the benzene ring (except monohalophenyl)), ##STR3## (wherein the dotted line indicates the optional presence of an additional single bond linkage, R.sup.5 is a hydrogen atom or a lower alkyl group and R.sup.6 and R.sup.7 are each a hydrogen atom, a halogen atom or a lower alkyl group), ##STR4## (wherein R.sup.8 is a hydrogen atom or a lower alkyl group and R.sup.Type: GrantFiled: May 9, 1977Date of Patent: December 1, 1981Assignee: Sumitomo Chemical Company, LimitedInventors: Kikuo Sasajima, Keiichi Ono, Masaru Nakao, Hisao Yamamoto
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Patent number: 4148796Abstract: Novel .gamma.-piperidinobutyrophenone derivatives of the formula, ##STR1## wherein R.sup.1 is halogen, amino, alkanoylamino, alkylamino or N-(alkanoyl)alkylamino;R.sup.2 is hydrogen or halogen, provided that when R.sup.1 is halogen, R.sup.2 must be halogen; andZ is a piperidino group having the formula (A), ##STR2## (wherein each of R.sub.a and R.sub.b is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl; R.sup.3 is hydrogen or hydroxyl; and n is 1 or 2), or a piperidino group having the formula (B), ##STR3## (wherein R.sub.c is hydrogen or lower alkyl; and each of R.sub.d and R.sub.e is hydrogen, halogen, lower alkyl or lower alkoxy), provided that when R.sup.1 is amino and R.sup.2 is hydrogen, Z cannot be represented by the formula (A), and their pharmaceutically acceptable acid addition salts, which are useful as psychotropic, neuroleptic or analgesic agents.Type: GrantFiled: August 15, 1973Date of Patent: April 10, 1979Assignee: Sumitomo Chemical Company, LimitedInventors: Hisao Yamamoto, Masaru Nakao, Kikuo Sasajima, Isamu Maruyama, Shigenari Katayama
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Patent number: 4080328Abstract: Novel N-substituted heterocyclic derivatives represented by the formula, ##STR1## wherein R is hydrogen or lower alkanoyl; R.sub.1 is hydrogen, lower alkyl, lower alkoxy, halogen, nitro, trifluoromethyl, amino or N-lower alkanoylamino; R.sub.2 is hydrogen, halogen, amino or N-lower alkanoylamino; W is oxygen, sulfur, sulfinyl or sulfonyl; and Y is ##STR2## (wherein R.sub.3 is hydrogen, lower alkyl or lower alkanoyl; and R.sub.4 is hydrogen, halogen or lower alkyl), and pharmaceutically acceptable salts thereof, which have excellent anti-inflammatory, analgesic, sedative, anti-convulsive or anti-hypertensive activities.Type: GrantFiled: June 28, 1974Date of Patent: March 21, 1978Assignee: Sumitomo Chemical Company, LimitedInventors: Isamu Maruyama, Masaru Nakao, Kikuo Sasajima, Shigeho Inaba, Izumi Yanagihara, Hisao Yamamoto
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Patent number: 4065565Abstract: Acylhydrazone compounds having excellent pyschotropic activity which are represented by the formula: ##STR1## wherein Z is selected from the groups having the formulas: ##STR2## wherein n is an integer of from 0 to 2 and R.sup.1 -R.sup.12 are as defined hereinbelow.Type: GrantFiled: August 12, 1975Date of Patent: December 27, 1977Assignee: Sumitomo Chemical Company, LimitedInventors: Kikuo Sasajima, Keiichi Ono, Masaru Nakao, Isamu Maruyama, Shigenari Katayama, Shigeho Inaba, Hisao Yamamoto
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Patent number: 4039670Abstract: Butyrophenone compounds having excellent psychotropic activities represented by the formula: ##STR1## wherein R.sup.1 is a halogen atom, R.sup.2 is a lower alkyl group, and Z is a group of either one of the formulae: ##STR2## (wherein the dotted line indicates the optional presence of an additional single bond linkage, R.sup.3 is a hydrogen atom or a hydroxyl group but only when said additional single bond linkage is not present and R.sup.4 is a hydrogen atom or a phenyl or benzyl group optionally substituted with one or two substituents selected from the group consisting of halogen, lower alkyl, lower alkyoxy and trifluoromethyl on the benzene ring (except monohalophenyl)), ##STR3## (wherein the dotted line indicates the optional presence of an additional single bond linkage, R.sup.5 is a hydrogen atom or a lower alkyl group and R.sup.6 and R.sup.7 are each a hydrogen atom, a halogen atom or a lower alkyl group), ##STR4## (wherein R.sup.8 is a hydrogen atom or a lower alkyl group and R.sup.Type: GrantFiled: April 17, 1975Date of Patent: August 2, 1977Assignee: Sumitomo Chemical Co., Ltd.Inventors: Kikuo Sasajima, Keiichi Ono, Masaru Nakao, Hisao Yamamoto
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Patent number: 4017624Abstract: An N-(.omega.-amino)alkylaniline derivative of the formula: ##STR1## and its pharmaceutically acceptable salts, which are useful as neuroleptic agents and can be prepared by reacting a compound of the formula: ##STR2## with a compound of the formula:H--A[wherein R is hydrogen, C.sub.1 -C.sub.7 alkyl, C.sub.1 -C.sub.7 alkanoyl or aroyl, R.sub.1 is hydrogen, halogen, C.sub.1 -C.sub.7 alkyl or C.sub.1 -C.sub.7 alkoxy,A is ##STR3## (wherein R.sub.2 is hydrogen, halogen, C.sub.1 -C.sub.7 alkyl, C.sub.1 -C.sub.7 alkoxy or trifluoromethyl), ##STR4## (wherein R.sub.2 is as defined above and R.sub.3 is hydrogen, C.sub.1 -C.sub.7 alkyl or C.sub.1 -C.sub.7 alkanoyl), ##STR5## (wherein R.sub.2 is as defined above or ##STR6## (wherein R.sub.2 and R.sub.3 are each as defined above) and n is 2, 3 or 4].Type: GrantFiled: August 8, 1975Date of Patent: April 12, 1977Assignee: Sumitomo Chemical Company, LimitedInventors: Isamu Maruyama, Masaru Nakao, Kikuo Sasajima, Shigeho Inaba, Hisao Yamamoto
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Patent number: 4012514Abstract: Novel olefinic aryl ketone compounds of the formula: ##STR1## wherein R.sup.1 is hydrogen, halogen, C.sub.1-4 alkyl, or C.sub.1-4 alkoxy, R.sup.2 is hydrogen or halogen, and X is a group of the formula: ##STR2## and their non-toxic salts, which possess various useful pharmacological activities and can be produced by reaction of an acetylenic alcohol of the formula: ##STR3## wherein R.sup.1 and R.sup.2 are each as defined above with formaldehyde and an piperidine compound of the formula: , or its non-toxic salt; reduction of the resultant acetylenic aryl alcohol; and oxidation of the resultant olefinic aryl alcohol.Type: GrantFiled: July 29, 1975Date of Patent: March 15, 1977Assignee: Sumitomo Chemical Company, LimitedInventors: Junki Katsube, Masaru Nakao, Kikuo Sasajima, Isamu Maruyama, Masaharu Takayama, Keiichi Ono, Shigenari Katayama, Yoshihiro Tanaka, Shigeho Inaba, Hisao Yamamoto
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Patent number: 4012515Abstract: Novel olefinic aryl ketone compounds of the formula: ##STR1## wherein R.sup.1 is hydrogen, halogen, C.sub.1.sub.-4 alkyl, or C.sub.1.sub.-4 alkoxy, R.sup.2 is hydrogen or halogen, and R.sup.3 and R.sup.4 are each hydrogen, halogen, C.sub.1.sub.-4 alkyl or trifluoromethyl, and their non-toxic salts, which possess various useful pharmacological activities and can be produced by reaction of an acetylenic alcohol of the formula: ##STR2## wherein R.sup.1 and R.sup.2 are each as defined above, with formaldehyde and an amine of the formula: ##STR3## wherein R.sup.3 and R.sup.4 are each as defined above; reduction of the resultant acetylenic aryl alcohol; and oxidation of the resultant olefinic aryl alcohol.Type: GrantFiled: July 29, 1975Date of Patent: March 15, 1977Assignee: Sumitomo Chemical Company, LimitedInventors: Junki Katsube, Masaru Nakao, Kikuo Sasajima, Isamu Maruyama, Masaharu Takayama, Keiichi Ono, Shigenari Katayama, Yoshihiro Tanaka, Shigeho Inaba, Hisao Yamamoto
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Patent number: 4010280Abstract: A phenoxyalkylamine derivative of the formula: ##STR1## and its pharmaceutically acceptable salts, which are useful as neuroleptic agents and a process for their preparation by reacting a compound of the formula: ##STR2## with a compound of the formula: ##STR3## wherein R.sub.1 and R.sub.2 are each hydrogen, halogen, C.sub.1 -C.sub.7 alkyl or C.sub.1 -C.sub.7 alkoxy, X is oxygen, sulfur, sulfinyl or NR (in which R is hydrogen or C.sub.1 -C.sub.7 alkyl), m and n are each an integer of 2, 3 or 4, and Y and Y' are each amino or halogen but they are different from each other.Type: GrantFiled: September 27, 1974Date of Patent: March 1, 1977Assignee: Sumitomo Chemical Company, LimitedInventors: Isamu Maruyama, Masaru Nakao, Kikuo Sasajima, Shigeho Inaba, Hisao Yamamoto
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Patent number: 4009173Abstract: Novel butyrophenone derivatives of the formula: ##STR1## wherein R.sub.1 represents a hydroxyl group or ##STR2## (wherein R.sub.6 and R.sub.7 are each a hydrogen atom or a lower alkyl group or, when taken together with the adjacent nitrogen atom, may form a heterocyclic group), R.sub.2 represents an optionally substituted phenyl group or ##STR3## (wherein R.sub.8 and R.sub.9 are each a hydrogen atom or a lower alkyl group or, when taken together with the adjacent nitrogen atom, may form a heterocyclic group), R.sub.4 represents a hydrogen atom, a lower alkyl group or an optionally substituted phenyl group, R.sub.5 represents a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group or a trifluoromethyl group, R.sub.10 represents a hydrogen atom or an acyl group represented by R.sub.3 CO- (wherein R.sub.3 is a hydrogen atom, a lower alkyl group or an optionally substituted phenyl group) and Z represents two hydrogen atoms or an oxygen atom, provided that when Z is an oxygen atom and R.sub.Type: GrantFiled: September 29, 1975Date of Patent: February 22, 1977Assignee: Sumitomo Chemical Company, LimitedInventors: Kikuo Sasajima, Masaru Nakao, Isamu Maruyama, Keiichi Ono, Shigenari Katayama, Shigeho Inaba, Hisao Yamamoto
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Patent number: 4009275Abstract: Phenoxypropylamine derivatives of the formula: ##STR1## (in which R.sub.2 is a halogen atom or a trifluoromethyl group) and R.sub.1 is a halogen atom or a C.sub.1 -C.sub.4 alkyl or C.sub.2 -C.sub.4 alkenyl group, and their pharmaceutically acceptable salts, which are useful as neuroleptic agents and can be prepared by reacting a compound of the formula: ##STR2## wherein X is a halogen atom and R.sub.1 is as defined above with a compound of the formula:H-Ywherein Y is as defined above.Type: GrantFiled: February 28, 1975Date of Patent: February 22, 1977Assignee: Sumitomo Chemical Company, LimitedInventors: Isamu Maruyama, Masaru Nakao, Kikuo Sasajima, Shigeho Inaba, Hisao Yamamoto
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Patent number: 4001312Abstract: Novel 4-amino-1-butanol derivatives having excellent depressant activity on central nervous system. A preferred compound of the disclosure is 4-[2-(2-alkoxyphenoxy)ethylamino]-1-(4-fluorophenyl)-1-butanol and its pharmaceutically acceptable salts.Type: GrantFiled: August 14, 1974Date of Patent: January 4, 1977Assignee: Sumitomo Chemical Company, LimitedInventors: Masaru Nakao, Kikuo Sasajima, Isamu Maruyama, Shigenari Katayama, Hisao Yamamoto
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Patent number: 3993780Abstract: Novel phenoxyethylamine derivatives of the formula: ##SPC1##Wherein R.sub.1 and R.sub.2 are each hydrogen, halogen, C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy, R.sub.3 is hydrogen or C.sub.1 -C.sub.4 alkyl, R.sub.4 and R.sub.5 are each hydrogen or C.sub.1 -C.sub.4 alkoxy and R is alkyl or aralkyl, and non-toxic pharmaceutically acceptable salts thereof, which are useful as central nervous system depressants and anti-hypertensive agents and can be prepared by reducing a compound of the formula: ##SPC2##Wherein R.sub.1, R.sub.2, R.sub.4, R.sub.5 and R are each as defined above and A is ##EQU1## (wherein R.sub.3 is as defined above) with a reducing agent.Type: GrantFiled: October 18, 1974Date of Patent: November 23, 1976Assignee: Sumitomo Chemical Company, LimitedInventors: Masaru Nakao, Kikuo Sasajima, Isamu Maruyama, Shigenari Katayama, Hisao Yamamoto
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Patent number: 3979390Abstract: A process for producing butyrophenone derivatives of the formula: ##EQU1## which comprises reacting a compound of the formula: ##SPC1##With an amine of the formulaH-W(wherein Ar represents a group of either one of the formulas: ##SPC2##Z is a secondary amino group and W is the residue of an amine excluding a hydrogen atom therefrom). The said butyrophenone derivatives and their salts exhibit a variety of beneficial pharmacological activities including a central and autonomic nervous system depressing activity.Type: GrantFiled: March 16, 1973Date of Patent: September 7, 1976Assignee: Sumitomo Chemical Company, LimitedInventors: Kikuo Sasajima, Keiichi Ono, Masaru Nakao, Isamu Maruyama, Masaharu Takayama, Shigenari Katayama, Junki Katsube, Shigeho Inaba, Hisao Yamamoto
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Patent number: 3965106Abstract: A 3-phenoxypropylamine derivative of the formula: ##SPC1##Wherein Y is ##SPC2##(wherein R.sub.1 is a halogen atom or a trifluoromethyl group) or ##SPC3##(wherein R.sub.2 is a lower alkyl group) and its pharmaceutically acceptable salts which are useful as central nervous system depressing agents.Type: GrantFiled: December 12, 1973Date of Patent: June 22, 1976Assignee: Sumitomo Chemical Company, LimitedInventors: Isamu Maruyama, Masaru Nakao, Kikuo Sasajima, Shigeho Inaba, Hisao Yamamoto
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Patent number: 3960873Abstract: Novel N-substituted heterocyclic derivatives represented by the formula, ##SPC1##Wherein R.sub.1 is hydrogen atom, lower alkyl, lower alkoxy, nitro, halogen or trifluoromethyl group; R.sub.2 is hydrogen atom or lower alkyl group; X is sulfur atom, sulfinyl or sulfonyl group; Y is ##EQU1## group (wherein R.sub.3 is phenyl or substituted phenyl group; R.sub.4 is hydrogen atom, hydroxy, lower alkyl, lower alkoxy, lower alkanoyl, lower alkanoyloxy, carbamoyl, N-(lower alkyl)-carbamoyl or N,N-di(lower akyl)-carbamoyl group; R.sub.5 is hydrogen atom, morpholino, pyrrolidinyl, piperidinyl, hexamethylenimino, lower alkyl, cyclo(lower alkyl), cyclo(lower alkyl)-(lower alkyl), hydroxy-(lower alkyl), (lower alkoxy)-(lower alkyl), phenyl or substituted phenyl group; k is 0 or 1 and m is 0, 1 or 2); and n is 3 or 4, and pharmaceutically acceptable salts thereof, which have excellent tranquillizing, anti-psychotonic, anti-emotional, anti-convulsive, anti-psychosis, sedative, analgesic or anti-hypertensive activities.Type: GrantFiled: June 21, 1974Date of Patent: June 1, 1976Assignee: Sumitomo Chemical Co., Ltd.Inventors: Isamu Maruyama, Hisao Yamamoto, Masaru Nakao, Shigeru Sakai, Kikuo Sasajima, Sumio Kitagawa, Shigeho Inaba
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Patent number: 3951986Abstract: 2-Propanol derivatives of the formula: ##SPC1##And their pharmaceutically acceptable acid addition salts, which are useful as medicaments and can be produced by reacting a compound of the formula: A-CH.sub.2 -Z with a compound of the formula: A'-H [wherein R is hydrogen or lower alkanoyl; R.sub.1 is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl; W is oxygen, sulfur, sulfinyl or sulfonyl; Y is a group of either one of the formulae: ##SPC2##(wherein R.sub.2 is hydrogen, halogen, lower alkyl or lower alkoxy and R.sub.3 is hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl); A and A' are each a group of either one of the formulae: ##SPC3##(wherein R.sub.1, W and Y are each as defined above), provided that A and A' are different each other; and Z is a group of either one of the formulae: ##EQU1## (wherein X is halogen, alkylsulfonyloxy or arylsulfonyloxy and R is as defined above)].Type: GrantFiled: June 18, 1973Date of Patent: April 20, 1976Assignee: Sumitomo Chemical Company, LimitedInventors: Isamu Maruyama, Masaru Nakao, Kikuo Sasajima, Shigeho Inaba, Hisao Yamamoto
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Patent number: 3936468Abstract: Butyrophenone derivatives having excellent psychotropic activity and represented by the formula, ##SPC1##Wherein A represents a single or double bond linkage; R.sub.1 represents a hydrogen atom or a C.sub.1 - C.sub.4 alkyl group; R.sub.2, which is present only in case A represents a single bond linkage, represents a hydrogen atom, or a hydroxyl, C.sub.1 - C.sub.4 alkyl, or C.sub.1 - C.sub.4 alkoxy group; R.sub.3 represents a hydrogen atom, or a piperidino, pyrrolidino, morpholino, furyl, thienyl, C.sub.1 - C.sub.4 alkylamino, benzylamino, unsubstituted or halogen-substituted phenyl group, etc.; and X represents a hydrogen or halogen atom, or a C.sub.1 - C.sub.4 alkyl, C.sub.1 - C.sub.4 alkoxy, or trifluoromethyl group, can be prepared by reducing a benzoylpropionamide derivative of the formula, ##SPC2##Wherein A, R.sub.1, R.sub.2, R.sub.Type: GrantFiled: February 15, 1973Date of Patent: February 3, 1976Assignee: Sumitomo Chemical Company, Ltd.Inventors: Hisao Yamamoto, Masaru Nakao, Kikuo Sasajima, Isamu Maruyama, Shigenari Katayama
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Patent number: 3933824Abstract: Central nervous system active butyrophenone derivatives in which .gamma. -piperazinobutyrophenone derivatives of the formula, ##SPC1##Wherein R.sup.1 is hydrogen, amino, C.sub.1 -C.sub.5 alkanoylamino, C.sub.1 -C.sub.4 alkylamino or N-(C.sub.1 -C.sub.4 alkyl)(C.sub.1 -C.sub.5 alkanoyl) amino; R.sup.2 is hydrogen or halogen; R.sup.3 is hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or trifluoromethyl; and m is 0, 1 or 2, and acid addition salts thereof, can be prepared by reacting an indole derivative of the formula, ##SPC2##Wherein R.sup.2, R.sup.3 and m are the same as defined above, and R.sup.4 and R.sup.5 are hydrogen or C.sub.1 -C.sub.4 alkyl respectively, with an oxidizing agent to yield an o-alkanoylamino-.gamma.-piperazinobutyrophenone derivative of the formula, ##SPC3##Wherein R.sup.2, R.sup.3, R.sup.4, R.sup.5 and m are the same as defined above, and further, if necessary, hydrolyzing the product to yield an o-amino-.gamma.Type: GrantFiled: January 22, 1973Date of Patent: January 20, 1976Assignee: Sumitomo Chemical Company, LimitedInventors: Hisao Yamamoto, Masaru Nakao, Kikuo Sasajima, Isamu Maruyama, Shigenari Katayama