Patents by Inventor Masaru Otani
Masaru Otani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20150164968Abstract: Provided is a method of producing a banana-derived composition by which a composition exhibiting excellent biological activity is obtained from a flesh part of a banana. The method includes the steps of (1) mincing a flesh part of a banana to obtain flesh fractions; (2) adding a proteolytic enzyme to the flesh fractions and decomposing proteins contained in the flesh fractions through an enzyme reaction, to obtain an enzymatic reactant; and (3) deactivating the proteolytic enzyme contained in the enzymatic reactant to obtain a composition A.Type: ApplicationFiled: November 13, 2014Publication date: June 18, 2015Inventor: Masaru Otani
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Patent number: 6342243Abstract: An amino acid and/or a peptide are orally administrated to a neonatal ruminant whose fermenting function of the rumen has not yet developed thereby effecting a significant increase in the accumulation of fat between the muscle fibers as well as increase of the fattening effect during the fattening period.Type: GrantFiled: October 14, 1998Date of Patent: January 29, 2002Assignee: Ajinomoto Co., Inc.Inventors: Michio Takahashi, Toru Sawasaki, Masaru Otani, Shinichi Suzuki
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Patent number: 5329014Abstract: Optically active tryptophan of high purity can be obtained in high yields from a tryptophan fermentation broth, using crystallization of optically active tryptophan hydrochloride in combination with concurrent neutralization crystallization. According to the present invention, optically active tryptophan from a tryptophan containing fermentation broth, is carried out by (a) removing cells from the fermentation broth, adding hydrochloric acid, or a mixture of hydrochloric acid and an inorganic salt which contains chloride ions, to the cell-free broth to effect crystallization, (b) separating optically active tryptophan hydrochloride, (c) dissolving the optically active tryptophan hydrochloride, and (d) subjecting the resulting solution and an alkali solution to concurrent neutralization crystallization, maintaining a pH of the crystallization solution in the range of from 3 to 8.Type: GrantFiled: July 31, 1991Date of Patent: July 12, 1994Assignee: Ajinomoto Co., Inc.Inventors: Toru Shinohara, Masaru Otani
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Patent number: 4962193Abstract: A biological process for producing a 2',3'-dideoxynucleoside from 2',3'-dideoxyuridine is disclosed. the 2',3'-dideoxynucleoside can be purified readily using a porous nonpolar resin adsorbent.Type: GrantFiled: December 28, 1988Date of Patent: October 9, 1990Assignee: Ajinomoto Co., Inc.Inventors: Kenzo Yokozeki, Hideyuki Shirae, Hiroshi Shiragami, Yasuo Irie, Naohiko Yasuda, Masaru Otani, Toshiya Tanabe
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Patent number: 4835104Abstract: A biological process for producing a 2',3'-dideoxyncleoside from 2',3'-dideoxyuridine is disclosed. The 2',3'-dideoxynucleoside can be purified readily using a porous nonpolar resin adsorbent.Type: GrantFiled: May 9, 1988Date of Patent: May 30, 1989Assignee: Ajinomoto Co., Inc., Patent & Licensing DepartmentInventors: Kenzo Yokozeki, Hideyuki Shirae, Hiroshi Shiragami, Yasuo Irie, Naohiko Yasuda, Masaru Otani, Toshiya Tanabe
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Patent number: 4820869Abstract: A method for separating leucine from a mixture of amino acids containing at least leucine and isoleucine, which comprises subjecting an aqueous solution of a mixture of amino acids to centrifugal force, and forcing by the application of pressure a water-saturated organic solvent immiscible with water to pass through the aqueous solution against the centrifugal force, to selectively extract leucine in said water-saturated organic solvent.Type: GrantFiled: December 29, 1987Date of Patent: April 11, 1989Assignee: Ajinomoto Co., Inc.Inventors: Masaru Otani, Masami Kojima, Toshio Kitahara
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Patent number: 4584400Abstract: A process for refining phenylalanine, in which a phenylalanine solution containing tyrosine as the main impurity and other impurities is contacted with a non-polar, highly porous synthetic adsorbent, adsorbing phenylalanine on the adsorbent selectively, and eluting and recovering the adsorbed phenylalanine, is disclosed.Type: GrantFiled: December 6, 1984Date of Patent: April 22, 1986Assignee: Ajinomoto Co., Inc.Inventors: Masaru Otani, Chiaki Sano, Isao Kusumoto
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Patent number: 4423218Abstract: Antibiotic neplanocin A of the formula ##STR1## is produced by culturing Ampullariella sp. A 11079 FERM-P No. 4494 in a nutrient medium and then separating the neplanocin A thus produced from the culture medium.Type: GrantFiled: November 3, 1980Date of Patent: December 27, 1983Assignee: Toyo Jozo Kabushiki KaishaInventors: Masaru Otani, Satoshi Yaginuma, Masatoshi Tsujino, Naoki Muto, Tetsu Saito, Tadashiro Fujii
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Patent number: 4349667Abstract: Aminoglycoside antibiotic G-367-2 believed to have the formula ##STR1## is produced by culturing Dactylosporangium thailandense G-367 FERM-P No. 4840 in a nutrient medium and separating the produced antibiotic therefrom. It has strong antibacterial effect against Gram negative bacteria.Type: GrantFiled: July 9, 1980Date of Patent: September 14, 1982Assignee: Toyo Jozo Kabushiki KaishaInventors: Tadashiro Fujii, Shuzo Satoi, Naoki Muto, Mitsuo Hayashi, Akira Kodama, Masaru Otani
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Patent number: 4321376Abstract: Neplanocin-B and -F of the formula ##STR1## in which Y is oxygen or a valence bond, are produced by culturing Ampullariella sp. A 11079 FERM-P No. 4494 in a nutrient medium and then separating the neplanocin-B and -F thus produced from the culture medium.Type: GrantFiled: December 7, 1979Date of Patent: March 23, 1982Assignee: Toyo Jozo Kabushiki KaishaInventors: Masaru Otani, Satoshi Yaginuma, Masatoshi Tsujino, Naoki Muto, Tetsu Saito, Tadashiro Fujii
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Patent number: 4297486Abstract: Aminoglycoside antibiotic G-367-1 believed to have the formulae ##STR1## is produced by culturing Dactylosporangium thailandense G-367 FERM-P No. 4840 in a nutrient medium and separating the produced antibiotic therefrom. It has strong antibacterial effect against Gram negative bacteria.Type: GrantFiled: April 3, 1980Date of Patent: October 27, 1981Assignee: Toyo Jozo Kabushiki KaishaInventors: Tadashiro Fujii, Shuzo Satoi, Naoki Muto, Mitsuo Hayashi, Akira Kodama, Masaru Otani
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Patent number: 4291021Abstract: A novel microorganism species belonging to the genus Micromonospora, i.e. Micromonospora sp. A 11725 is found to be capable of producing novel macrolide antibiotics A 11725 I, A 11725 II and A 11725 III. Novel antibiotics A 11725 Ia and A 11725 IIa are also found to be derived by chemical modification of the antibiotics A 11725 I and A 11725 II, respectively. All of these antibiotics or salts thereof exhibit excellent antibacterial and anti-mycoplasmal activities against various microorganisms such as Staphylococcus or Mycoplasma, and therefore useful for various purposes including medicaments.Type: GrantFiled: May 10, 1979Date of Patent: September 22, 1981Assignee: Toyo Jozo Company, Ltd.Inventors: Masaru Otani, Shuzo Satoi, Naoki Muto, Tetsu Saito, Tadashiro Fujii, Seiji Katsumata, Mitsuo Hayashi, Masaru Ono
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Patent number: 4254256Abstract: An amino sugar compound represented by the general formula: ##STR1## (wherein m is an integer of 0 to 8, n is an integer of 1 to 8 and m+n is an integer of 1 to 8) has strong glycosidase inhibiting action and is produced by culturing an amino sugar compound producing microorganisms belonging to Streptomyces.Type: GrantFiled: December 12, 1978Date of Patent: March 3, 1981Assignee: Toyo Jozo company, Ltd.Inventors: Masaru Otani, Tetsu Saito, Shuzo Satoi, Junzo Mizoguchi, Naoki Muto
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Patent number: 4212858Abstract: Antibiotics aculeacin-A.alpha., -A.gamma., -D.alpha. and -D.gamma. are active against yeasts and fungi. They are produced by culturing the microorganism Aspergillus aculeatus NRRL 11270 in a nutrient medium containing assimilable carbon and nitrogen sources.Type: GrantFiled: April 19, 1978Date of Patent: July 15, 1980Assignee: Toyo Jozo Kabushiki KaishaInventors: Masaru Otani, Shuzo Satoi, Masaki Takada
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Patent number: 3988309Abstract: A polypeptide having calcitonin activity of the formula ##EQU1## and the salts thereof with pharmaceutically acceptable acids.Type: GrantFiled: December 17, 1974Date of Patent: October 26, 1976Assignee: Toyo Jozo Kabushiki KaishaInventors: Tetsuo Matsuda, Susumu Watanabe, Shunpei Sakakibara, Eisuke Munekata, Tadanori Morikawa, Masaru Otani, Toshiharu Noda, Hirose Yamauchi, Tosio Meguro, Shuichi Kitazawa
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Patent number: RE35609Abstract: A biological process for producing a 2',3'-dideoxynucleoside from 2',3'-dideoxyuridine is disclosed. The 2',3'-dideoxynucleoside can be purified readily using a porous nonpolar resin absorbent.Type: GrantFiled: February 9, 1995Date of Patent: September 16, 1997Assignee: Ajinomoto Co., Inc.Inventors: Masaru Otani, Toshiya Tanabe