Patents by Inventor Masaru Saita

Masaru Saita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6063029
    Abstract: A diagnostic patch comprising at least an adsorption carrier adsorbing a substance secreted from a living body, which is useful particularly for the diagnosis of mammary cancer or atopic dermatitis, and a method for the diagnosis of mammary cancer or atopic dermatitis with said preparation.
    Type: Grant
    Filed: April 29, 1996
    Date of Patent: May 16, 2000
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Masaru Saita, Yuji Shimozono, Shigeo Ohta, Keishi Yonemura, Mizue Mukai, Akira Okayama, Shuhei Imayama
  • Patent number: 5519046
    Abstract: A fomentation containing ketorolac, one of nonsteroidal anti-inflammatory analgesics, or a salt thereof as the efficacious ingredient, and a base comprising a water-soluble high-molecular substance, a humectant, water and, if necessary, an absorption promoter.
    Type: Grant
    Filed: May 6, 1994
    Date of Patent: May 21, 1996
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Kanji Noda, Masaru Saita, Munehiko Hirano, Yasuhiro Ikeura, Yasuaki Taniguchi, Terushi Hashiguchi, Yasuhisa Kose, Yasunori Takada, Eiji Kyoya, Akira Nakagawa
  • Patent number: 5449783
    Abstract: A novel diphenythiazole derivative represented by the following general formula (I): ##STR1## wherein m and n are each 1 or 2; R.sup.1 and R.sup.2 represent each a hydrogen atom, a lower alkyl group, a lower alkoxy group, a lower alkylsulfenyl group, a nitro group, an amino group, a methanesulfonyloxy group or a halogen atom; A.sup.1 represents a lower alkanesulfonyl group, a halogenated lower alkanesulfonyl group, a substituted benzenesulfonyl group, a lower acyl group or a halogenated lower acyl group; and A.sup.2 represents a hydrogen atom, a lower alkanesulfonyl group, a halogenated lower alkanesulfonyl group or a lower alkyl group,and being efficacious as a drug having antiinflammatory, analgesic, antiallergic, uricosuric or platelet aggregation inhibiting effects.
    Type: Grant
    Filed: August 23, 1993
    Date of Patent: September 12, 1995
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Masaru Saita, Hisataka Inoue, Kouichi Ikesue, Noriyuki Fujimoto, Ikuo Shinohara, Taniguchi: Yasuaki, Yoshiki Deguchi, Hidenao Minami, Kanji Noda
  • Patent number: 5434292
    Abstract: A novel phenylalkanoic acid derivative represented by the following formula ##STR1## wherein n is an integer of 1-2, X is a halogen atom, alkoxyl group or nitro group, R is a hydrogen atom or alkyl group, and Z is a hydrogen atom or acyl group,a method for producing said derivative, a method for separating the optical isomers of said derivative from each other, as well as an anti-inflammatory drug, analgesic drug or preparation for external use each containing said derivative.
    Type: Grant
    Filed: February 4, 1994
    Date of Patent: July 18, 1995
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Masaru Saita, Hisataka Inoue, Koichi Beppu, Terumi Hachiya, Ikuo Shinohara, Yasuaki Taniguchi, Yoshiki Deguchi, Yoshihiro Hamaguchi
  • Patent number: 5407911
    Abstract: A parathyroid hormone-containing emulsion for nasal administration, comprising parathyroid hormone as the active ingredient, at least, azacycloalkane derivative of the general formula [1]: ##STR1## wherein R is alkyl, m is an integer of 2-4, and n is an integer of 1-15, provided that R is alkyl of C.sub.5-11 in case where n is 1-3, as the absorption promotor, glycyrrhizic acid or its non-toxic salt, and a suitable amount of water.
    Type: Grant
    Filed: May 16, 1994
    Date of Patent: April 18, 1995
    Assignees: Asahi Kasei Kogyo Kabushiki Kaisha, Hisamitsu Keiyaku Kabushiki Kaisha
    Inventors: Nakayuki Yamamoto, Michihiko Sugimoto, Seiki Morimoto, Hideo Sakakibara, Masaru Saita, Yuji Shimozono, Takafumi Manako
  • Patent number: 5371238
    Abstract: A process for producing an azacycloalkane derivative represented by the following general formula (II): ##STR1## wherein m is an integer of from 1 to 3, n.sub.2 is an integer of from 2 to 10, andR represents an alkyl group having 3 to 12 carbon atoms,characterized by reacting a 1-(n-alkenyl)-azacycloalkan-2-one represented by the following general formula (I): ##STR2## wherein m is an integer of from 1 to 3, and n.sub.1 is an integer of from 0 to 8,with an alkyl mercaptan in the presence of a radical initiator in an organic solvent, treating the reaction mixture thus obtained with a reducing agent in a water-containing organic solvent, and then purifying the treated mixture by distillation.
    Type: Grant
    Filed: April 23, 1993
    Date of Patent: December 6, 1994
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Masaru Saita, Hisataka Inoue, Terumi Hachiya, Shigenori Yahiro, Kanji Noda
  • Patent number: 5281580
    Abstract: The present invention is to provide emulsion preparations for nasal administration containing calcitonins, which are safely and effectively administrated compared with the conventional calcitonin preparations. The emulsions are prepared by using a calcitonin as the active ingredient, an azacycloalkane derivative as the absorption promotor such as 1-[2-(decylthio)ethyl] azacyclopentan-2-one, and glycyrrhizic acid or its salt.
    Type: Grant
    Filed: July 23, 1991
    Date of Patent: January 25, 1994
    Assignees: Toyo Jozo Company, Ltd., Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Nakayuki Yamamoto, Michihiko Sugimoto, Hideo Sakakibara, Masaru Saita, Yuji Shimozono, Takafumi Manako
  • Patent number: 5175286
    Abstract: A dibenz[b,e]oxepin derivative represented by the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 are each hydrogen, halogen, lower alkyl or alkoxy; one of R.sup.3 and R.sup.4 is lower alkoxy, and other is a group represented by the formula (II) ##STR2## wherein R.sup.5 is hydrogen or lower alkyl, A is hydroxyl, --O(CH.sub.2).sub.m --R.sup.6 (wherein m is an integer of 1-6, R.sup.6 is hydrogen, lower alkyl or alkoxy, cycloamino, or lower alkoxycarbonyl), cycloamino, di-lower alkylamino or --NH(CH.sub.2).sub.n --R.sup.7 (wherein n is an integer of 0-3, R.sup.7 is hydrogen, hydroxyl, phenyl, thiazole or cycloamino).
    Type: Grant
    Filed: March 8, 1991
    Date of Patent: December 29, 1992
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Masaru Saita, Hisataka Inoue, Terumi Hachiya, Mikio Nakashima, Shigenori Yahiro, Yasuaki Taniguchi, Yoshiki Deguchi, Shoji Hamanaka, Masayoshi Tsuji, Kanji Noda
  • Patent number: 4895956
    Abstract: A novel 3-aroyl-6,7-dihydro-5H-pyrrolo[1,2-c]imidazole-7-carboxylic acid derivative which is useful as a medicine having excellent analgesic and anti-inflammatory actions with remarkably less toxicity and side-effects.
    Type: Grant
    Filed: September 8, 1988
    Date of Patent: January 23, 1990
    Assignee: Hisamitsu Pharmaceutical Co., Ltd.
    Inventors: Masayoshi Tsuji, Hisataka Inoue, Yoshihiro Tanoue, Kouichi Beppu, Masaru Saita, Yasuaki Taniguchi, Kenichi Furuta, Yoshiki Deguchi, Kanji Noda
  • Patent number: 4877876
    Abstract: This invention provides an indenothiazole derivative and a process for manufacturing the same. The said indenothiazole derivative is represented by the following formula: ##STR1## wherein X and Y are identical with, or different from, each other and are each a hydrogen atom, halogen atom, low alkyl group or low alkoxy group; n is an integer of from 0 to 4; R.sub.1 is a hydrogen atom, low alkyl group, unsubstituted or substituted phenyl group; R.sub.2 is a low alkyl group, cycloalkyl group, low alkoxyl group, unsubstituted or substituted phenoxy group, unsubstituted or substituted phenyl group, alkenyl group, heterocyclic group or cycloamino group; R.sub.3 is a hydrogen atom, low alkyl group or acyl group; and R.sub.2 and R.sub.3 may be combined to form a cycloamino group. Further, this invention also provides a tautomer of the compound represented by the above formula (Ia), wherein all the symbols are as defined above except that R.sub.3 is limited to a hydrogen atom.
    Type: Grant
    Filed: August 31, 1987
    Date of Patent: October 31, 1989
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Masayoshi Tsuji, Akira Nakagawa, Hisataka Inoue, Terumi Hachiya, Yoshihiro Tanoue, Kouichi Ikesue, Masaru Saita, Takenobu Mizoguchi, Testsuo Aoki, Hironobu Sato, Kanji Nodo