Patents by Inventor Masaru Suetsugu
Masaru Suetsugu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8003083Abstract: The present invention is benzilidene malonamide represented by the following formula (1) and salts thereof, an ultraviolet absorbent consisting of said new compound, and an external preparation containing this ultraviolet absorbent. The object of the present invention is to provide a new ultraviolet absorbent that is highly soluble in water, has superior absorption capacity over a wide ultraviolet wavelength range, has no absorption in the visible region, and is also highly stable and safe.Type: GrantFiled: June 11, 2007Date of Patent: August 23, 2011Assignee: Shiseido Company, Ltd.Inventors: Takuya Hiruma, Masaru Suetsugu
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Publication number: 20110065794Abstract: A wrinkle-preventing and -improving composition comprising one or more than one compound selected from the group consisting of ?-amino acid derivatives represented by the following general formula (1) and salts thereof: wherein, R1 represents hydrogen atom, CH3 group or CH2OH group, R2 and R3 each independently represent hydrogen atom, alkyl group having 1 to 4 carbons, provided that R2 and R3 cannot be hydrogen atom at the same time, or R2 and R3 together with N atom to which they are bound may form a ring structure having a total carbon number of 4 to 6, in which case said ring structure may optionally contain an oxygen atom as a heteroatom, R4 represents hydrogen atom, alkyl group having 1 to 18 carbons, wherein when R1 and R4 are hydrogen atom, it cannot be that one of R2 and R3 is benzyloxycarbonyl group and the other is hydrogen atom.Type: ApplicationFiled: November 12, 2010Publication date: March 17, 2011Applicant: Shiseido Company, Ltd.Inventors: Makoto Tsunenaga, Haruhi Iwaki, Toshii Iida, Mikiko Kaminuma, Masaru Suetsugu, Keiko Takada, Shinji Inomata
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Publication number: 20110004019Abstract: The present invention provides a parakeratosis inhibitor, a pore-shrinking agent, and a rough skin inhibiting or ameliorating agent comprising, as an active ingredient, a compound that has excellent effects and high safety without safety problems such as sensory irritation, and provides an external composition for skin containing the same. The compound is selected from the glutamic acid derivatives represented by formula (1) or (2) and the salts thereof: wherein A represents a carbamoyl group, a benzyloxycarbonyl group, an alkyl group having 1 to 3 carbon atoms, an allyl group, or an amidino group; wherein Z represents an alkyl group having 1 to 4 carbon atoms, an alkenyl group having 2 to 4 carbon atoms, etc.Type: ApplicationFiled: March 12, 2009Publication date: January 6, 2011Applicant: SHISEIDO COMPANY LTD.Inventors: Toshii Iida, Maki Kaneko, Mikiko Kaminuma, Masaru Suetsugu
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Publication number: 20100254921Abstract: The present invention is benzilidene malonamide represented by the following formula (1) and salts thereof, an ultraviolet absorbent consisting of said new compound, and an external preparation containing this ultraviolet absorbent. The object of the present invention is to provide a new ultraviolet absorbent that is highly soluble in water, has superior absorption capacity over a wide ultraviolet wavelength range, has no absorption in the visible region, and is also highly stable and safe.Type: ApplicationFiled: June 11, 2007Publication date: October 7, 2010Applicant: SHISEIDO COMPANY, LTD.Inventors: Takuya Hiruma, Masaru Suetsugu
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Publication number: 20100168468Abstract: A wrinkle-preventing and -improving composition comprising one or more than one compound selected from the group consisting of ?-amino acid derivatives represented by the following general formula (1) and salts thereof: wherein, R1 represents hydrogen atom, CH3 group or CH2OH group, R2 and R3 each independently represent hydrogen atom, alkyl group having 1 to 4 carbons, provided that R2 and R3 cannot be hydrogen atom at the same time, or R2 and R3 together with N atom to which they are bound may form a ring structure having a total carbon number of 4 to 6, in which case said ring structure may optionally contain an oxygen atom as a heteroatom, R4 represents hydrogen atom, alkyl group having 1 to 18 carbons, wherein when R1 and R4 are hydrogen atom, it cannot be that one of R2 and R3 is benzyloxycarbonyl group and the other is hydrogen atom.Type: ApplicationFiled: July 26, 2006Publication date: July 1, 2010Applicant: Kyowa Hakko Kirin Co., Ltd.Inventors: Makoto TSUNENAGA, Haruhi IWAKI, Toshii IDIDA, Mikiko KAMINUMA, Masaru SUETSUGU, Keiko TAKADA, Shinji INOMATA
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Publication number: 20100113450Abstract: The present invention provides an agent for preventing and alleviating wrinkles which has excellent effects of preventing and alleviating wrinkles formed by decreased barrier function of the skin owing to aging or photo aging, that is graphic wrinkles or linear wrinkles. The agent for preventing and alleviating wrinkles consisting of one or more compounds selected from the group consisting of gamma-aminobutyric acid derivatives represented by the following formula (1) or N,N,N-trimethyl gamma-aminobutyric acid represented by the following formula (3) and salts thereof: wherein R1 and R2 independently represent any of a hydrogen atom, an alkyl group having 1 to 3 carbon atoms, a benzyloxycarbonyl group, a cyclohexyl group, a cyclohexanemethyl group, a cyclohexanecarbonyl group, a guanidino group formed with nitrogen atom in the formula (1), an ureido group formed with nitrogen atom in the formula (1), and a group represented by following formula (2).Type: ApplicationFiled: March 14, 2008Publication date: May 6, 2010Applicant: SHISEIDO COMPANY LTD.Inventors: Makoto TSUNENAGA, Mikiko KAMINUMA, Masaru SUETSUGU, Chika KATAGIRI
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Publication number: 20100113590Abstract: Disclosed is an ADAM inhibitor which enables to prevent or improve conditions caused by increase in ADAM activity. Specifically disclosed is an ascorbic acid derivative represented by the general formula (1) below or a salt thereof. [chemical formula 1] (1), wherein R represents a linear or branched alkyl group having 1 to 22 carbon atoms.Type: ApplicationFiled: December 27, 2007Publication date: May 6, 2010Applicant: Shiseido Company, Ltd.Inventors: Takuya Hiruma, Hirotada Fukunishi, Masaru Suetsugu, Yukiko Matsunaga, Satoshi Amano, Michio Shibata
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Publication number: 20100094054Abstract: The present invention provides a composition for external application to skin containing one type or two or more types of compounds selected from the group consisting of aminoacetoamide compounds represented by the following general formula (1) and salts thereof.Type: ApplicationFiled: January 24, 2008Publication date: April 15, 2010Inventors: Mikiko Kaminuma, Masaru Suetsugu, Nobuhiko Ochiai, Makoto Tsunenaga
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Publication number: 20100087535Abstract: A moisturizing agent comprising one or more than one compound selected from the group consisting of lysyl-?-alanine represented by the following general formula (1) and a salt thereof:Type: ApplicationFiled: March 19, 2008Publication date: April 8, 2010Inventors: Makoto Tsunenaga, Nobuhiko Ochiai, Mikiko Kaminuma, Masaru Suetsugu
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Publication number: 20100035831Abstract: Disclosed is an anti-wrinkle agent for ameliorating a wrinkle (particularly a fine wrinkle) developed when the barrier function is decreased by dryness and the like. Also disclosed is an ADAM inhibitor. The anti-wrinkle agent or the ADAM inhibitor comprises an alkyl glucoside represented by the general formula: (1) [wherein R represents a linear or branched alkyl group having 1 to 18 carbon atoms] or a salt thereof.Type: ApplicationFiled: December 27, 2007Publication date: February 11, 2010Applicant: SHISEIDO COMPANY, LTD.Inventors: Yukiko Matsunaga, Satoshi Amano, Takuya Hiruma, Hirotada Fukunishi, Masaru Suetsugu, Michio Shibata
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Publication number: 20100035881Abstract: The invention provides a novel wrinkle-improving agent that has an effect of improving wrinkles, that does not entail problems of safety or pain even when applied to the skin, and that contains a very safe substance as an active component. A discovery was made that N-benzoyl-?-alanine, other specific ?-alanine derivatives, and salts thereof have a wrinkle-improving effect, whereby a wrinkle-improving agent containing as an active component one, two, or more types of compounds selected from the group composed of these specific ?-alanine derivatives and the salts thereof was developed.Type: ApplicationFiled: September 15, 2006Publication date: February 11, 2010Applicant: SHISEIDO COMPANY, LTD.Inventors: Mikiko Kaminuma, Masaru Suetsugu, Makoto Tsunenaga, Kiyotaka Hasegawa, Shinji Inomata
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Publication number: 20090233975Abstract: A hair resiliency and body improver comprising as the active ingredient thereof one or more types of compounds selected from the group consisting of 2-aminothiazole derivatives represented by the following general formula (1) or 3-aminoisoxazole derivatives represented by the following general formula (2), and pharmaceutically acceptable salts thereof: (wherein, R1, R2, R3, R4, n and m are as defined in the description).Type: ApplicationFiled: July 21, 2006Publication date: September 17, 2009Inventors: Masaru Suetsugu, Hirotada Fukuniahi, Masato Iino, Satoshi Yamaki, Tsutomu Soma
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Publication number: 20090215893Abstract: The invention provides a parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/amaliorating agent that has a function such as parakeratosis inhibition, pore shrinkage, or rough skin-inhibition/abatement, poses no safety problems such as sensory irritation, and is very safe, and to further provide an external composition for skin to which a compound having the above-mentioned function has been added. The parakeratosis inhibitor agent, pore-shrinking agent, or rough skin preventing/amaliorating agent comprises one, two, or more compounds selected from the group consisting of ?-amino acid derivatives and salts thereof. The external composition for skin comprises the one, two, or more compounds selected from the group consisting of ?-amino acid derivatives and salts thereof as the above-mentioned parakeratosis inhibitor, pore-shrinking agent, or rough skin preventing/amaliorating agent.Type: ApplicationFiled: May 9, 2006Publication date: August 27, 2009Applicant: Shiseido Company LtdInventors: Mikiko Kaminuma, Masaru Suetsugu, Maki Kaneko, Toshii Iida, Shinji Inomata
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Publication number: 20070225380Abstract: To provide a parakeratosis inhibitor, pore reducing agent and skin roughness preventing/ameliorating agent that exhibit capabilities of parakeratosis inhibition, pore reduction, skin roughness prevention/amelioration, etc., and further provide a skin preparation for external use having these capabilities. There are provide a parakeratosis inhibitor and a pore reducing agent each comprising at least one compound selected from the group consisting of a glycine derivative, an aminodicarboxylic acid derivative, an acylaminodicarboxylic acid derivative, a pyrrolidinecarboxylic acid derivative, a piperidinecarboxylic acid derivative, a hexamethyleneiminecarboxylic acid, a beta-alanine derivative and salts of these derivatives.Type: ApplicationFiled: November 22, 2004Publication date: September 27, 2007Applicant: Shiseido Company Ltd.Inventors: Mikiko Kaminuma, Masaru Suetsugu, Toshii Iida, Shinji Inomata, Keiko Takada, Yuji Katsuta
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Publication number: 20060257436Abstract: An external skin treatment composition containing, based upon the total weight of the composition, 0.001% by mass or more of a diol compound of formula (I), (II), (III), or (IV) or the derivative thereof and a balance of a carrier: wherein R indicates a benzyl group or a phenyl group.Type: ApplicationFiled: April 2, 2004Publication date: November 16, 2006Applicant: Shiseido Company, Ltd.Inventors: Mikimo Kaminuma, Masaru Suetsugu, Shigeyuki Ogawa, Eriko Yokota, Eijiro Hara
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Patent number: 6676932Abstract: Providing an ultraviolet absorbent or photostabilizer with excellent absorption over a wide ultraviolet wavelength range and great stability and a high safety profile, as well as an ultraviolet-absorbing composition, a photostabilized composition and an external preparation for skin, where the pyridazine derivative of the following general formula and/or a salt thereof is included as the effective component of the ultraviolet absorbent or photostabilizer, or is included in the ultraviolet-absorbing composition, the photostabilized composition and the external preparation for skin: Wherein R1, R2, R3 and R4 are not simultaneously hydrogen atom; and R2 and R3 are not simultaneously morpholino group.Type: GrantFiled: June 13, 2002Date of Patent: January 13, 2004Assignee: Shiseido Co., Ltd.Inventors: Masaru Suetsugu, Eijiro Hara
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Publication number: 20030198608Abstract: Providing an ultraviolet absorbent or photostabilizer with excellent absorption over a wide ultraviolet wavelength range and great stability and a high safety profile, as well as an ultraviolet-absorbing composition, a photostabilized composition and an external preparation for skin, where the pyridazine derivative of the following general formula and/or a salt thereof is included as the effective component of the ultraviolet absorbent or photostabilizer, or is included in the ultraviolet-absorbing composition, the photostabilized composition and the external preparation for skin: 1Type: ApplicationFiled: June 13, 2002Publication date: October 23, 2003Applicant: Shiseido Co., Ltd.Inventors: Masaru Suetsugu, Eijiro Hara
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Patent number: 6476024Abstract: Ultraviolet absorbents and photostabilizers have an excellent absorption ability in a wide range of ultraviolet rays, and also have high stability and high safety. The ultraviolet absorbent and photostabilizer include a pyridazine derivative of the formula (1): or salts thereof. Also, described are methods for manufacturing said pyridazine derivative and/or this salts thereof comprising the process of reacting at least 10 wt % of 4,5-dichloro-3-hydroxypyridazine or 4,5-dibromo-3-hydroxypyridazine or mixtures thereof with at least 20 vol % of morpholine in reaction solution at 70° C. or higher. The ultraviolet absorbents photostabilizers include said pyridazine derivative and/or salts thereof as effective ingredient. An ultraviolet ray absorption composition and an external preparation for skin are also included.Type: GrantFiled: March 4, 2002Date of Patent: November 5, 2002Assignee: Shiseido Co. Ltd.Inventors: Masaru Suetsugu, Eijiro Hara, Yuji Matsushita, Haruhiko Inoue, Haruo Ogawa, Keiko Sakai, Shigeru Mugikura
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Patent number: 6395896Abstract: Ultraviolet absorbents and photostabilizers have an excellent absorption ability in a wide range of ultraviolet rays, and also have high stability and high safety. The ultraviolet absorbent and photostabilizer include a pyridazine derivative of the formula (1): or salts thereof. Also, described are methods for manufacturing said pyridazine derivative and/or this salts thereof comprising the process of reacting at least 10 wt % of 4,5-dichloro-3-hydroxypyridazine or 4,5-dibromo-3-hydroxypyridazine or mixtures thereof with at least 20 vol % of morpholine in reaction solution at 70° C. or higher. The ultraviolet absorbents photostabilizers include said pyridazine derivative and/or salts thereof as effective ingredient. An ultraviolet ray absorption composition and an external preparation for skin are also included.Type: GrantFiled: December 15, 2000Date of Patent: May 28, 2002Assignee: Shiseido Co., Ltd.Inventors: Masaru Suetsugu, Eijiro Hara, Yuji Matsushita, Haruhiko Inoue, Haruo Ogawa, Keiko Sakai, Shigeru Mugikura
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Publication number: 20010012841Abstract: Ultraviolet absorbents and photostabilizers have an excellent absorption ability in a wide range of ultraviolet rays, and also have high stability and high safety.Type: ApplicationFiled: December 15, 2000Publication date: August 9, 2001Inventors: Masaru Suetsugu, Eijiro Hara, Yuji Matsushita, Haruhiko Inoue, Haruo Ogawa, Keiko Sakai, Shigeru Mugikura