Patents by Inventor Masaru Sugimachi
Masaru Sugimachi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230380704Abstract: A blood pressure monitoring apparatus including a linear relationship storage portion storing previously stored linear relationships, a blood pressure measurement portion measuring a real arterial pressure of the person to be measured, a proper relationship generation portion applying, for the person to be measured, the real arterial pressure, real compression pressures, and real pulse wave propagation velocities, to thereby generate a proper relationship on the person to be measured among the real arterial pressures of the person to be measured, the real compression pressures, and the real pulse wave propagation velocities, and a blood pressure estimation portion applying, for the person to be measured, the real compression pressures and the real pulse wave propagation velocities obtained under the real compression pressures, to the proper relationship on the person to be measured, to thereby estimate the estimated arterial pressure.Type: ApplicationFiled: October 11, 2021Publication date: November 30, 2023Applicants: A&D COMPANY, LIMITED, NATIONAL CEREBRAL AND CARDIOVASCULAR CENTERInventors: Naotaka HASEBE, Shohei MORODOME, Masaki FURUKOSHI, Kazunori UEMURA, Masaru SUGIMACHI, Takuya NISHIKAWA
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Patent number: 9655529Abstract: A left atrial pressure measurement device includes: a measurement section that measures a first index value that indicates performance of a right ventricle, and a second index value that indicates performance of a left ventricle; and a calculation section that calculates a left atrial pressure using the first index value, the second index value, and a measured right atrial pressure.Type: GrantFiled: February 6, 2014Date of Patent: May 23, 2017Assignees: SEIKO EPSON CORPORATION, NATIONAL CEREBRAL AND CARDIOVASCULAR CENTERInventors: Mikio Aoki, Kazunori Uemura, Masaru Sugimachi
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Publication number: 20160345930Abstract: A first blood vessel diameter and a second blood vessel diameter are measured using a first ultrasonic probe and a second ultrasonic probe that are provided close to a blood vessel of a subject so as to be situated at a given distance (Lp). Characteristic phases of a pulse wave are determined from the peak of a second-order differential value of the first blood vessel diameter and the peak of a second-order differential value of the second blood vessel diameter, and the difference (?t) in pulse wave transit time is calculated from the difference in timing between the characteristic phases to calculate pulse wave velocity (PWV). A given calculation process that uses the pulse wave velocity (PWV) and the measured blood vessel diameter as variables is performed to calculate blood pressure.Type: ApplicationFiled: May 16, 2016Publication date: December 1, 2016Applicants: SEIKO EPSON CORPORATION, NATIONAL CEREBRAL AND CARDIOVASCULAR CENTERInventors: Hiromitsu MIZUKAMI, Kazunori UEMURA, Masaru SUGIMACHI
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Publication number: 20140228683Abstract: A left atrial pressure measurement device includes: a measurement section that measures a first index value that indicates performance of a right ventricle, and a second index value that indicates performance of a left ventricle; and a calculation section that calculates a left atrial pressure using the first index value, the second index value, and a measured right atrial pressure.Type: ApplicationFiled: February 6, 2014Publication date: August 14, 2014Applicants: National Cerebral and Cardiovascular Center, SEIKO EPSON CORPORATIONInventors: Mikio AOKI, Kazunori UEMURA, Masaru SUGIMACHI
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Publication number: 20130303916Abstract: A processing device included in a cardiac output monitoring system includes an arterial diameter measurement ultrasonic probe that is attached to a neck of a subject, and measures the diameter of the carotid artery, and an arterial diameter measurement control section. A carotid artery diameter control section analyzes an ultrasonic echo to calculate the diameter of the artery (DOA), and outputs the diameter of the artery (DOA) to an ejection time/mean arterial pressure calculation section. The ejection time/mean arterial pressure calculation section calculates the ejection time (ET) from a temporal change in the diameter of the artery (DOA), and calculates the cardiac output. The temporal change waveform of the diameter of the artery (DOA) is clearer than the waveform of the blood flow velocity in the aorta or the ventricular outflow tract measured using an ultrasonic Doppler method, and the ejection time (ET) can be automatically calculated with high accuracy.Type: ApplicationFiled: May 1, 2013Publication date: November 14, 2013Inventors: Mikio AOKI, Kazunori UEMURA, Masaru SUGIMACHI
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Patent number: 8340749Abstract: A cardiac disease treating system has an input part for inputting a patient's indexes of kinetics of blood circulation including at least heart rate, a cardiac oxygen consumption calculation monitor unit for calculating the estimated value of said patient's amount of cardiac oxygen consumption based on the indexes of kinetics of blood circulation input from the input part, and a cardiac oxygen consumption curtailment unit for comparing the heart rate input from the input part and the critical heart rate minimizing the estimated value of amount of cardiac oxygen consumption calculated by the cardiac oxygen consumption monitor unit and controlling the patient's heart rate in conformity with the results of this comparison.Type: GrantFiled: February 16, 2007Date of Patent: December 25, 2012Assignees: Japan Health Sciences Foundation, FUJIKIN IncorporatedInventors: Masaru Sugimachi, Kazunori Uemura, Atsunori Kamiya, Kenji Sunagawa, Michio Yamaji
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Patent number: 8282563Abstract: Problems To provide a cardiac disease treatment system for accurately diagnosing the functional cause of an abnormality of a cardiac disease by analyzing the hemodynamic state of a patient, automatically performing medication in accordance with the diagnosis result, and treating the cardiac disease. Means for solving problems The cardiac disease treatment system is characterized by comprising input means (2) for inputting the cardiac output value of the patient, the left atrial pressure value and/or the right atrial pressure value, first calculating means (31) for calculating the pumping ability value of the left heart or the right heart from the inputted cardiac output and the left or right atrial pressure value, first comparing means (41) for comparing the pumping ability value of the left heart or the right heart with a target pumping ability value, and first medicating means (51) for medicating the patient in accordance with the result of the comparison by the first comparing means (41).Type: GrantFiled: November 18, 2004Date of Patent: October 9, 2012Assignee: Japan Health Sciences FoundationInventors: Kazunori Uemura, Atsunori Kamiya, Masaru Sugimachi, Kenji Sunagawa
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Patent number: 8262581Abstract: A practical method for estimating cardiac output and pulmonary artery wedge pressure with good accuracy is provided. A method is provided for estimating the impedance arising from solid tissue by determining the impedance at the intersection between the line of identity and the extrapolated regression line, where the regression line is obtained by linearly regressing the maximum value to the minimum value of the impedance signal of each of multiple data sets, where each data set contains the maximum value and the minimum value of the impedance signal during one cardiac cycle, where impedance signal is obtained between a can electrode implanted in the left thoracic wall and an electrode inserted into the coronary vein, over a specific period of time following the infusion of hypertonic saline into the pulmonary circulation.Type: GrantFiled: December 4, 2007Date of Patent: September 11, 2012Assignees: National Cerebral and Cardiovascular Center, Olympus CorporationInventors: Kazunori Uemura, Masashi Inagaki, Masaru Sugimachi, Kazuo Shimizu, Masatoshi Kobayashi
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Patent number: 8027729Abstract: A micro integrated cardiac pacemaker includes a control unit for outputting a control signal according to cardiograph information, heart stimulating means for stimulating heart tissue in response to the control signal, cardiograph information extracting means for extracting cardiograph information and outputting it to the control unit, and a power supply unit for supplying drive power. The power supply unit is a biological fuel cell that takes out electrons by oxidation of a biological fuel. The biological fuel cell includes an anode and a cathode. An oxidase of a biological fuel and a mediator are immobilized on the cathode. Blood and/or body fluid are used as an electrolytic solution, and a biological fuel and oxygen in the blood and/or the fluid are used. The biological fuel cell is attached to the end of a catheter and implanted into the heart, and the catheter is withdrawn, without incising the breast.Type: GrantFiled: August 4, 2003Date of Patent: September 27, 2011Assignees: National Cerebral and Cardiovascular Center, Fujikin CorporatedInventors: Kenji Sunagawa, Masaru Sugimachi, Masashi Inagaki
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Patent number: 8010195Abstract: The present invention provides a cardiac pacing system based on biological activities, comprising: a) at least one nerve activity sensing means which senses nerve activity of a cardiac sympathetic nerve and/or a vagal nerve, and outputs a plurality of input nerve activity signals; b) a calculating means which receives the input nerve activity signals, calculates a transfer function by computing a Fourier transform of normal nerve activity signals and a normal heart rate signal from normal cardiovascular system, calculates an impulse response by computing an inverse Fourier transform of the transfer function, calculates a plurality of pacing signals for control of a heart rate using a convolution integral between the input nerve activity signals and the impulse response, and outputs the pacing signals; and c) a pacing means which receives the pacing signals, and stimulates the heart based on the pacing signals such that heart rate is regulated.Type: GrantFiled: February 18, 2011Date of Patent: August 30, 2011Assignees: National Cerebral and Cardiovascular Center, Fujikin Inc.Inventors: Kenji Sunagawa, Masaru Sugimachi, Takayuki Sato
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Patent number: 8010199Abstract: A blood pressure regulating system uses a native regulation rule to estimate at least one nerve activity in response to blood pressure changes, comprising at least one blood pressure sensing means which senses blood pressure and outputs a input blood pressure signal, a calculating means which receives the input blood pressure signal, calculates a transfer function by computing a Fourier transform of a normal blood pressure signal and a normal sympathetic nerve activity from normal cardiovascular system, calculates an impulse response by computing an inverse Fourier transform of the transfer function, calculates a sympathetic nerve stimulation signal using a convolution integral between the input blood pressure signal and the impulse response, and outputs the sympathetic nerve stimulation signal, and a stimulating means which receives the sympathetic nerve stimulation signal, and stimulates the sympathetic nerve innervating vascular beds based on the sympathetic nerve stimulation signal such that blood pressurType: GrantFiled: February 23, 2011Date of Patent: August 30, 2011Assignees: National Cerebral and Cardiovascular Center, Fujikin Inc.Inventors: Kenji Sunagawa, Masaru Sugimachi, Takayuki Sato
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Patent number: 8000791Abstract: A distributed cardiac pacing system comprises a first ultra miniature integrated cardiac pacemaker adapted to be placed in an atrial myocardium and a second ultra miniature integrated cardiac pacemaker adapted to be placed in a ventricular myocardium.Type: GrantFiled: April 15, 2008Date of Patent: August 16, 2011Assignees: National Cerebral and Cardiovascular Center, Fujikin Inc.Inventors: Kenji Sunagawa, Masaru Sugimachi, Masashi Inagaki
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Publication number: 20110144714Abstract: A blood pressure regulating system uses a native regulation rule to estimate at least one nerve activity in response to blood pressure changes, comprising at least one blood pressure sensing means which senses blood pressure and outputs a input blood pressure signal, a calculating means which receives the input blood pressure signal, calculates a transfer function by computing a Fourier transform of a normal blood pressure signal and a normal sympathetic nerve activity from normal cardiovascular system, calculates an impulse response by computing an inverse Fourier transform of the transfer function, calculates a sympathetic nerve stimulation signal using a convolution integral between the input blood pressure signal and the impulse response, and outputs the sympathetic nerve stimulation signal, and a stimulating means which receives the sympathetic nerve stimulation signal, and stimulates the sympathetic nerve innervating vascular beds based on the sympathetic nerve stimulation signal such that blood pressurType: ApplicationFiled: February 23, 2011Publication date: June 16, 2011Applicants: NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER, FUJIKIN INCORPORATEDInventors: Kenji SUNAGAWA, Masaru SUGIMACHI, Takayuki SATO
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Publication number: 20110144710Abstract: The present invention provides a cardiac pacing system based on biological activities, comprising: a) at least one nerve activity sensing means which senses nerve activity of a cardiac sympathetic nerve and/or a vagal nerve, and outputs a plurality of input nerve activity signals; b) a calculating means which receives the input nerve activity signals, calculates a transfer function by computing a Fourier transform of normal nerve activity signals and a normal heart rate signal from normal cardiovascular system, calculates an impulse response by computing an inverse Fourier transform of the transfer function, calculates a plurality of pacing signals for control of a heart rate using a convolution integral between the input nerve activity signals and the impulse response, and outputs the pacing signals; and c) a pacing means which receives the pacing signals, and stimulates the heart based on the pacing signals such that heart rate is regulated.Type: ApplicationFiled: February 18, 2011Publication date: June 16, 2011Applicants: NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER, FUJIKIN INCORPORATEDInventors: Kenji SUNAGAWA, Masaru SUGIMACHI, Takayuki SATO
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Patent number: 7962216Abstract: A medical treating system based on biological activities characterized by biological activity sensing means for sensing biological activity information produced by biological activities and outputting a biological activity signal, calculating means for receiving, analyzing, and processing the biological activity signals from the biological activity sensing means, calculating an organism stimulation signal, and outputting the organism stimulation signal, and organism stimulating means for receiving the organism stimulation signal calculated by the calculating means and stimulating an organism according to the organism stimulation signal. A cardiac pacing system based on the treating system, a blood pressure regulating system, and a cardiac disease treating system are also disclosed.Type: GrantFiled: April 16, 2008Date of Patent: June 14, 2011Assignees: National Cerebral and Cardiovascular Center, Fujikin, Inc.Inventors: Kenji Sunagawa, Masaru Sugimachi, Takayuki Sato
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Publication number: 20110098767Abstract: [PROBLEMS] A system for automatically minimizing cardiac oxygen consumption that is capable of estimating a patient's amount of cardiac oxygen consumption with high accuracy and moreover capable of minimizing the amount of cardiac oxygen consumption and a cardiac disease treating system are provided.Type: ApplicationFiled: February 16, 2007Publication date: April 28, 2011Applicants: JAPAN HEALTH SCIENCES FOUNDATION, FUJIKIN INCORPORATEDInventors: Masaru Sugimachi, Kazunori Uemura, Atsunori Kamiya, Kenji Sunagawa, Michio Yamaji
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Publication number: 20110034782Abstract: [Problems] To provide an apparatus for a body surface stimulation treatment capable of overcoming the uncertainty in the existing body surface stimulation therapy and exhibiting stable therapeutic effects. [Means for Solving Problems] An apparatus for a body surface stimulation treatment (10) which comprises a body surface stimulation unit (16) whereby the body surface of a patient is physically or chemically stimulated, a vital reaction quantitative evaluation unit (12) whereby the vital reaction of the patient is quantitatively evaluated, and a body surface stimulation regulation unit (14) whereby the stimulation properties imparted to the body surface tissues of the patient by the body surface stimulation unit (16) are regulated depending on the vital data obtained by the vital reaction quantitative evaluation unit (12).Type: ApplicationFiled: November 29, 2006Publication date: February 10, 2011Applicant: FUJIKIN CORPORATIONInventors: Masaru Sugimachi, Atsunori Kamiya, Kenji Sunagawa
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Patent number: 7835791Abstract: A medical treating system based on biological activities characterized by biological activity sensing means for sensing biological activity information produced by biological activities and outputting a biological activity signal, calculating means for receiving, analyzing, and processing the biological activity signals from the biological activity sensing means, calculating an organism stimulation signal, and outputting the organism stimulation signal, and organism stimulating means for receiving the organism stimulation signal calculated by the calculating means and stimulating an organism according to the organism stimulation signal. A cardiac pacing system based on the treating system, a blood pressure regulating system, and a cardiac disease treating system are also disclosed.Type: GrantFiled: August 5, 2002Date of Patent: November 16, 2010Assignees: Fujikin Incorporated, National Cerebral and Cardiovascular CenterInventors: Kenji Sunagawa, Masaru Sugimachi, Takayuki Sato
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Publication number: 20090221923Abstract: Problems To provide a cardiac disease treatment system for accurately diagnosing the functional cause of an abnormality of a cardiac disease by analyzing the hemodynamic state of a patient, automatically performing medication in accordance with the diagnosis result, and treating the cardiac disease. Means for Solving Problems The cardiac disease treatment system is characterized by comprising input means (2) for inputting the cardiac output value of the patient, the left atrial pressure value and/or the right atrial pressure value, first calculating means (31) for calculating the pumping ability value of the left heart or the right heart from the inputted cardiac output and the left or right atrial pressure value, first comparing means (41) for comparing the pumping ability value of the left heart or the right heart with a target pumping ability value, and first medicating means (51) for medicating the patient in accordance with the result of the comparison by the first comparing means (41).Type: ApplicationFiled: November 18, 2004Publication date: September 3, 2009Applicant: JAPAN HEALTH SCIENCES FOUNDATIONInventors: Kazunori Uemura, Atsumori Kamiya, Masaru Sugimachi, Kenji Sunagawa
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Publication number: 20080319502Abstract: A micro integrated cardiac pacemaker includes a control unit for outputting a control signal according to cardiograph information, heart stimulating means for stimulating heart tissue in response to the control signal, cardiograph information extracting means for extracting cardiograph information and outputting it to the control unit, and a power supply unit for supplying drive power. The power supply unit is a biological fuel cell that takes out electrons by oxidation of a biological fuel. The biological fuel cell includes an anode and a cathode. An oxidase of a biological fuel and a mediator are immobilized on the cathode. Blood and/or body fluid are used as an electrolytic solution, and a biological fuel and oxygen in the blood and/or the fluid are used. The biological fuel cell is attached to the end of a catheter and implanted into the heart, and the catheter is withdrawn, without incising the breast.Type: ApplicationFiled: April 15, 2008Publication date: December 25, 2008Applicants: JAPAN AS REPRESENTED BY PRESIDENT OF NATIONAL CARDIOVASCULAR CENTER, FUJIKIN INCORPORATEDInventors: Kenji SUNAGAWA, Masaru SUGIMACHI, Masashi INAGAKI