Patents by Inventor Masaru Ushijima

Masaru Ushijima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10012572
    Abstract: Provided is a technique for using an optical microscope image of an area on a sample to collect area-specific information characterizing each kind of biological tissue from imaging mass analysis data. On an optical image of a two-dimensional target area on a sample, a difference is examined in the kind of tissue or other features and areas are specified, each regarded as the same kind of tissue. When data processing is initiated, peak information is extracted, for each specified area, from mass spectrum data of all the measurement points. A peak method is applied to each area to extract peak information. Then, when a command to compare a set of areas is given, the peak information of those areas is collected. By comparing the peak information of different areas by a machine learning algorithm or similar judging technique, area-specific peak information is obtained, and this information is stored in memory.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: July 3, 2018
    Assignee: Japanese Foundation for Cancer Research, Keio University, National University Corporation Hamamatsu, and Shimadzu Co.
    Inventors: Masaaki Matsuura, Masaru Ushijima, Masatoshi Wakui, Mitsutoshi Setou, Shigeki Kajihara, Kiyoshi Ogawa
  • Publication number: 20120278037
    Abstract: Provided is a technique for using an optical microscope image of an area on a sample to collect area-specific information characterizing each kind of biological tissue from imaging mass analysis data. On an optical image of a two-dimensional target area on a sample, a difference is examined in the kind of tissue or other features and areas are specified, each regarded as the same kind of tissue. When data processing is initiated, peak information is extracted, for each specified area, from mass spectrum data of all the measurement points. A peak method is applied to each area to extract peak information. Then, when a command to compare a set of areas is given, the peak information of those areas is collected. By comparing the peak information of different areas by a machine learning algorithm or similar judging technique, area-specific peak information is obtained, and this information is stored in memory.
    Type: Application
    Filed: April 27, 2012
    Publication date: November 1, 2012
    Applicants: JAPANESE FOUNDATION FOR CANCER RESEARCH, SHIMADZU CORPORATION, National University Corporation Hamamatsu University School Of Medicine, KEIO UNIVERSITY
    Inventors: Masaaki MATSUURA, Masaru USHIJIMA, Masatoshi WAKUI, Mitsutoshi SETOU, Shigeki KAJIHARA, Kiyoshi OGAWA
  • Publication number: 20040236742
    Abstract: In a clustering apparatus comprising an input unit (1) supplied with a dataset including a plurality of samples, a data processing unit (4) for processing the samples to classify each sample into a class, and an output unit (3) for producing a processing result representative of classification, a parameter memory (51) in a memory unit (5) memorizes a target parameter obtained from past experiment. A parameter estimating section (24) of the data processing unit estimates a clustering parameter by the use of the target parameter memorized in the parameter memory. An unidentifiable sample detecting section (25) of the data processing unit detects a sample as an unidentifiable sample if posterior probabilities calculated for the sample by a probability density function produced by the clustering parameter estimated by the parameter estimating section are smaller than a predetermined value.
    Type: Application
    Filed: March 5, 2004
    Publication date: November 25, 2004
    Inventors: Maki Ogura, Masataka Andoh, Akira Saitoh, Yusaku Wada, Minoru Isomura, Masaru Ushijima, Satoshi Miyata, Masaaki Matsuura, Yoshio Miki, Shinto Eguchi, Hironori Fujisawa, Toshio Furuta