Patents by Inventor Masashi Chazono

Masashi Chazono has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for culturing Bordetella pertussis, a pertussis toxoid and a pertussis vaccine
    Patent number: 5139776
    Abstract: There is disclosed a method for culturing Bordetella pertussis in the presence of a cellulose and/or cellulose derivatives. The present method is useful for obtaining a mixed antigen comprising pertussis toxin and filamentous hemagglutinin in a large amount at low cost. From the antigen, there can be obtained a stable and effective pertussis toxoid to be used for a pertussis vaccine. There is also disclosed a vaccine comprising the pertussis toxoid as an active ingredient and a gelatin and/or gelatin derivatives as a stabilizing agent. The present vaccine is extremely stable and can be stored for a prolonged period of time.
    Type: Grant
    Filed: February 3, 1989
    Date of Patent: August 18, 1992
    Assignee: The Research Foundation for Microbial Diseases of Osaka University
    Inventors: Masashi Chazono, Iwao Yoshida, Takeo Konobe, Juichiro Osame, Keisuke Takaku
  • Method for culturing bordetella pertussis, a pertussis toxoid and a pertussis vaccine
    Patent number: 4849358
    Abstract: There is disclosed a method for culturing Bordetella pertussis in the prece of a cellulose and/or cellulose derivatives. The present method is useful for obtaining a mixed antigen comprising pertussis toxin and filamentous hemagglutinin in a large amount at low cost. From the antigen, there can be obtained a stable and effective pertussis toxoid to be used for a pertussis vaccine. There is also disclosed a vaccine comprising the pertussis toxoid as an active ingredient and a gelatin and/or gelatin derivatives as a stabilizing agent. The present vaccine is extremely stable and can be stored for a prolonged period of time.
    Type: Grant
    Filed: July 14, 1987
    Date of Patent: July 18, 1989
    Assignee: The Research Foundation for Microbial Diseases of Osaka University
    Inventors: Masashi Chazono, Iwao Yoshida, Takeo Konobe, Juichiro Osame, Keisuke Takaku