Patents by Inventor Masashi Fukayama

Masashi Fukayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cancer diagnosis and treatment of cancer using anti-ROBO1 antibody
    Patent number: 9644029
    Abstract: A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody that binds to ROBO1, as well as a pharmaceutical composition, a cell growth inhibitor and an anticancer agent comprising an antibody that binds to ROBO1 as an active ingredient are disclosed. Further, a method for inducing cell damages in a ROBO1 expressing cell and a method for inhibiting the growth of a ROBO1 expressing cell by bringing a ROBO1 expressing cell into contact with an antibody that binds to ROBO1, are disclosed. Furthermore, a method for monitoring progression of hepatitis by detecting ROBO1 protein is disclosed.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: May 9, 2017
    Assignees: Perseus Proteomics Inc., Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hiroyuki Aburatani, Yoshitaka Hippo, Akira Watanabe, Masashi Fukayama, Yukio Ito, Masahiro Arai, Hirotaka Ito, Toshihiko Ohtomo, Shin-ichi Funahashi, Yasuko Kinoshita
  • Cancer Diagnosis and Treatment of Cancer Using Anti-Robo 1 Antibody
    Publication number: 20150291694
    Abstract: A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody that binds to ROBO1, as well as a pharmaceutical composition, a cell growth inhibitor and an anticancer agent comprising an antibody that binds to ROBO1 as an active ingredient are disclosed. Further, a method for inducing cell damages in a ROBO1 expressing cell and a method for inhibiting the growth of a ROBO1 expressing cell by bringing a ROBO1 expressing cell into contact with an antibody that binds to ROBO1, are disclosed. Furthermore, a method for monitoring progression of hepatitis by detecting ROBO1 protein is disclosed.
    Type: Application
    Filed: December 11, 2014
    Publication date: October 15, 2015
    Applicants: Perseus Proteomics Inc., Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hiroyuki ABURATANI, Yoshitaka Hippo, Akira Watanabe, Masashi Fukayama, Yukio Ito, Masahiro Arai, Hirotaka Ito, Toshihiko Ohtomo, Shin-ichi Funahashi, Yasuko Kinoshita
  • Cancer diagnosis and treatment of cancer using anti-robo 1 antibody
    Patent number: 8940488
    Abstract: A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody that binds to ROBO1, as well as a pharmaceutical composition, a cell growth inhibitor and an anticancer agent comprising an antibody that binds to ROBO1 as an active ingredient are disclosed. Further, a method for inducing cell damages in a ROBO1 expressing cell and a method for inhibiting the growth of a ROBO1 expressing cell by bringing a ROBO1 expressing cell into contact with an antibody that binds to ROBO1, are disclosed. Furthermore, a method for monitoring progression of hepatitis by detecting ROBO1 protein is disclosed.
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: January 27, 2015
    Assignees: Perseus Proteomics Inc., Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hiroyuki Aburatani, Yoshitaka Hippo, Akira Watanabe, Masashi Fukayama, Yukio Ito, Masahiro Arai, Hirotaka Ito, Toshihiko Ohtomo, Shin-ichi Funahshi, Yasuko Kinoshita
  • Therapeutic Agent And Diagnostic Agent For Cholangiocarcinoma
    Publication number: 20080008710
    Abstract: Disclosed is a cholangiocarcinoma cell growth inhibitor comprising an anti-glypican-3 antibody as an active ingredient. Preferably, the anti-glypican-3 antibody has a cytotoxic activity such as an antibody-dependent cytotoxic (ADCC) activity and a complement-dependent cytotoxic (CDC) activity. Also disclosed is a diagnostic agent for diagnosis of cholangiocarcinoma comprising an anti-glypican-3 antibody.
    Type: Application
    Filed: September 3, 2004
    Publication date: January 10, 2008
    Inventors: Hiroyuki Aburatani, Masashi Fukayama, Naoko Yamauchi, Masami Suzuki, Atsuhiko Kato, Masayuki Tsuchiya
  • Cancer Diagnosis And Treatment Of Cancer Using Anti-Robo 1 Antibody
    Publication number: 20070212359
    Abstract: A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody that binds to ROBO1, as well as a pharmaceutical composition, a cell growth inhibitor and an anticancer agent comprising an antibody that binds to ROBO1 as an active ingredient are disclosed. Further, a method for inducing cell damages in a ROBO1 expressing cell and a method for inhibiting the growth of a ROBO1 expressing cell by bringing a ROBO1 expressing cell into contact with an antibody that binds to ROBO1, are disclosed. Furthermore, a method for monitoring progression of hepatitis by detecting ROBO1 protein is disclosed.
    Type: Application
    Filed: March 31, 2005
    Publication date: September 13, 2007
    Applicant: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Hiroyuki Aburatani, Yoshitaka Hippo, Akira Watanabe, Yukio Ito, Hirotaka Ito, Shin-ichi Funahashi, Masashi Fukayama, Masahiro Arai, Toshihiko Ohtomo, Yasuko Kinoshita