Abstract: An optical correction is predictively performed based on a result of AI learning previously performed by use of learning data including measurement data. The optical compensation system is provided with wavefront correction optics, a sensor and a controller. The wavefront correction optics corrects a wavefront of light that passes through a given optical path. The sensor obtains environmental information in the optical path. The controller calculates, based on the environmental information, a predicted wavefront disturbance of the light that has passed through the optical path and controls the wavefront correction optics so as to cancel the predicted wavefront disturbance.

Abstract: A material discharge device includes: a drive motor; a screw having a groove formation surface and configured to rotate; a barrel having a facing surface and formed with a communication hole through which a plasticized material flows; a heating unit configured to heat the material; a nozzle from which the material is injected to an outside; and a plurality of measurement units configured to measure a pressure or a temperature of the material. The measurement units are disposed at an outer periphery of a nozzle channel wall, and a thickness of the nozzle channel wall satisfies the following (1) or (2): (1) when the nozzle channel wall is made of a material containing iron as a main component, the thickness of the nozzle channel wall is 0.2 mm or more and 2.5 mm or less; and (2) when the nozzle channel wall is made of a material containing aluminum as a main component, the thickness of the nozzle channel wall is 0.2 mm or more and 4 mm or less.

Abstract: Provided is a pretreatment method for structural analysis of a protein, including chemical modifying and fragmenting a protein to be analyzed, in which in the fragmenting, the protein is treated at a temperature of 60 to 99° C. in the presence of a heat-resistant protease that has four or more cleavage sites and is soluble or immobilized on a carrier.

Abstract: Provided is a method for evaluating a sample, the method including using a mixture containing a sample including at least one member selected from the group consisting of cell support-derived components, a cell suspension containing cells, an evaluation sample obtained from a cell suspension, a sample containing a liquid and microcarriers for use in cell culture, and a sample containing a liquid obtained following treatment of microcarriers, together with at least one substance selected from the group consisting of an aromatic compound having at least one functional group selected from the group consisting of a hydroxyl group, an amino group, a nitro group and a carbonyl group, and a fluorescent dye.

Abstract: Objects of the disclosure are to provide a preanalysis treatment method for a sample, which can reduce mixing of a reagent into the sample, and to provide a sample pretreatment system capable of performing the preanalysis treatment method. An aspect of the present embodiment is a preanalysis treatment method for a sample, which includes a step A of mixing the sample and a reagent A containing a support and a reducing agent immobilized on the support, a step B of mixing the sample and a reagent B containing a support and an enzyme immobilized on the support, a step X-A of, after the step A, separating the reagent A and a supernatant from each other, and a step X-B of, after the step B, separating the reagent B and a supernatant from each other.

Abstract: A power amplifier circuit includes an amplifier transistor that amplifies a radio-frequency signal and outputs the radio-frequency signal, and a bias circuit that supplies a bias current to a base of the amplifier transistor. The bias circuit includes a bias current supply transistor, and an electrostatic capacity circuit whose electrostatic capacity varies in accordance with a temperature of the amplifier transistor and that is charged in a non-supply period during which the bias current is not supplied and discharges to a supply path for the bias current in a supply period during which the bias current is supplied. The supply period during which the bias current is supplied includes an amplification period during which the radio-frequency signal is amplified by the amplifier transistor. The bias current starts to be supplied before the amplifier transistor starts amplification.

Abstract: The present invention provides a biocompatible material improved in biocompatibility owing to adsorption of a peptide that has high adhesion with a resin and hardly separates from a surface of the resin, and a functional material including the biocompatible material. The biocompatible material includes a resin and a peptide adsorbed on the resin. The resin has methoxycarbonyl groups and methyl groups, and tryptophan or arginine accounts for 70% or more of amino acid residues in the peptide. As an alternative, the resin is a fluorinated resin, and 2,3,4,5,6-pentafluoro-phenylalanine, 3-(trifluoromethyl)alanine, serine, threonine, histidine, aspartic acid, glutamic acid, phenylalanine, or aspartic acid accounts for 40% or more of the amino acid residues in the peptide. The functional material includes the biocompatible material, and a functional substance. The functional substance is held on a surface of the biocompatible material or is released from the surface of the biocompatible material.

Abstract: An object of the present invention is to provide an adsorbent material having high dispersibility and reversibility. The adsorbent material has a polymer material having a plurality of functional groups ionizable in water and exhibiting no lower limit critical solution temperature, an adsorption site capable of interacting with a target substance, and a carrier.

Abstract: The purpose of the present invention is to solve conventional problems involving immunoisolation devices using a porous membrane as an immunoisolation membrane, such problems including fibrotic formation on the device surface, shortage of oxygen supplied to cells, and non-uniform distribution of cells. An immunoisolation device for transplantation is characterized by comprising: an immunoisolation membrane; and an oxygen supply mechanism and a three-dimensional cell support which are tightly enclosed inside the immunoisolation membrane by physical sealing, a biocompatible adhesive, or a combination thereof, wherein the immunoisolation membrane is a porous membrane provided with a hydrophilic layer on the outer surface, and the oxygen supply mechanism can supply oxygen to cells supported by the three-dimensional cell support through an oxygen permeable membrane.

Abstract: The purpose of the present invention is to provide an automatic culture system whereby cells can be released from a vessel by a simple constitution and damage on the cells can be minimized In the automatic culture system according to the present invention, cells are cultured in a stimulus-responsive culture vessel and then the cells are released from the culture vessel by stimulating the culture vessel with a solution which is supplied from another vessel (see FIG. 3).

Abstract: The present invention pertains to a means and method for, from a mixture (cell culture) of cells, a medium component, and a useful substance, recovering the first two using a single process. Specifically, the present invention pertains to a polypeptide modified with a stimulus-responsive polymer, characterized in that the stimulus-responsive polymer responds to a stimulus to induce a change in the physical properties of the modified polypeptide overall, and the change is reversible or pseudo-reversible.

Abstract: A cell culture apparatus (1) of the present invention comprises: a culture vessel (2) in which a cell culture medium comprising at least one of culture components composed of a conjugate with a stimuli-responsive polymer is stored and cells are cultured in the medium; a stimulus-applying mechanism (4) that applies a predetermined stimulus to the conjugate so as to induce a predetermined change of the stimuli-responsive polymer in response to the stimulus; and, a separation mechanism (5) that separates at least a part of the medium components except for the conjugate from the cell culture medium, while leaving the conjugate in the cell culture medium, on the basis of a property change of the stimuli-responsive polymer.

Abstract: An object of the present invention is to provide an adsorbent material having high dispersibility and reversibility. The adsorbent material has a polymer material having a plurality of functional groups ionizable in water and exhibiting no lower limit critical solution temperature, an adsorption site capable of interacting with a target substance, and a carrier.

Abstract: The present invention has a subject of desorbing a target substance under mild elusion conditions in affinity purification using a low molecular weight ligand. In the present invention, a polar auxiliary group is introduced to a site adjacent to the low molecular weight ligand to perturb a pKa value of a functional group in the low-molecular-weight ligand, thereby ionizing the low molecular weight ligand under mild pH conditions.

Abstract: The present invention addresses the problem of providing: a core-shell catalyst capable of achieving, when evaluated for a fuel cell, the catalytic activity anticipated from the catalyst activity value obtained using a rotating disc electrode (RDE); and a method for activating a core-shell catalyst in said manner. The present invention relates to a fuel cell catalyst, which is an electrode catalyst having a core-shell structure and is characterized in that at least 99% of the core member is covered by the shell member and the halogen content is not more than 5000 ppm. The present invention also relates to a method for activating said core-shell catalyst, the method comprising: a process for dispersing the core-shell catalyst in a dispersion solvent; a process for separating impurities from said core-shell catalyst by blowing a gas that has reducing properties or a mixed gas comprising same into said dispersion solvent; and a process for removing said impurities.

Abstract: (Problem) To provide an electrolyte film for fuel cells, capable of achieving both low resistance (film thinning) and high dimensional stability. (Solution) An electrolyte film for fuel cells, the electrolyte film comprising a polymeric electrolyte and a polytetrafluoroethylene (PTFE) porous film, characterized in that a material having an elastic modulus higher than that of the material constituting the PTFE porous film is composited on the inside surfaces of pores of the PTFE porous film, and the composited PTFE porous film has an elastic modulus of at least 150 MPa.

Abstract: A technology is provided that is capable of improving deterioration of a fuel cell due to non-stationary operation (startup/shutdown, fuel depletion). An anode-side catalyst composition comprising a catalyst having catalyst particles carried on electrically conductive material and an ion exchange resin, characterized in that the catalyst particle are formed of an alloy, of which oxygen reduction capability and water electrolysis are both lower than those of platinum, and which has hydrogen oxidation capability.

Abstract: (Problem) To provide an electrolyte film for fuel cells, capable of achieving both low resistance (film thinning) and high dimensional stability. (Solution) An electrolyte film for fuel cells, the electrolyte film comprising a polymeric electrolyte and a polytetrafluoroethylene (PTFE) porous film, characterized in that a material having an elastic modulus higher than that of the material constituting the PTFE porous film is composited on the inside surfaces of pores of the PTFE porous film, and the composited PTFE porous film has an elastic modulus of at least 150 MPa.

Abstract: A semiconductor module includes a circuit substrate, a first semiconductor device substrate that is mounted on the circuit substrate and that processes an input signal of a first frequency band, a second semiconductor device substrate that is mounted on the circuit substrate and that processes an input signal of a second frequency band, and a control device substrate that is arranged between the first and second semiconductor device substrates and that controls the first and second semiconductor device substrates.

Abstract: The present invention addresses the problem of providing: a core-shell catalyst capable of achieving, when evaluated for a fuel cell, the catalytic activity anticipated from the catalyst activity value obtained using a rotating disc electrode (RDE); and a method for activating a core-shell catalyst in said manner. The present invention relates to a fuel cell catalyst, which is an electrode catalyst having a core-shell structure and is characterized in that at least 99% of the core member is covered by the shell member and the halogen content is not more than 5000 ppm. The present invention also relates to a method for activating said core-shell catalyst, the method comprising: a process for dispersing the core-shell catalyst in a dispersion solvent; a process for separating impurities from said core-shell catalyst by blowing a gas that has reducing properties or a mixed gas comprising same into said dispersion solvent; and a process for removing said impurities.