Abstract: A cooling device includes at least one fin laminated body which extends in a first direction and includes fins laminated in a second direction perpendicular to the first direction, and a heat conductor which extends in the second direction and is inside the fin laminated body. A second-direction interval between adjacent ones of the fins on one side of the fin laminated body in the first direction is greater than another second-direction interval between adjacent ones of the fins on another side of the fin laminated body in the first direction.

Abstract: A heat conduction member includes a housing including a space therein, a wick structure located in the space, and a working fluid enclosed in the space. The housing includes one or more metal plates and a joint structure that connects the one or more metal plates. The joint structure includes two stacked metal plate layers and a boundary portion between the two metal plate layers. The boundary portion includes a first region including crystal grains straddling the two metal plate layers.

Abstract: An unmanned aerial vehicle in which a circle drawn by a tip of a main propeller and a circle drawn by a tips of each of a plurality of auxiliary propellers axially overlap at least partially, a rotational direction of the plurality of auxiliary propellers is opposite to a rotational direction of the main propeller when viewed from one axial side of a main shaft, and a torque acting on a body from the main propeller when the body is hovering in the air is equal or substantially equal to a sum of torque acting on the body from the plurality of auxiliary propellers.

Abstract: Disclosed is a method for detecting lipid bilayer membrane particles or fragments thereof, having predetermined molecules existing on surfaces thereof, in a biological sample collected from a subject, the method comprising: adding to the biological sample a dye that stains a lipid bilayer membrane; adding a substance that specifically binds to the predetermined molecules; trapping the substance bound to the predetermined membrane molecules and separating unbound components; and detecting the separated stained lipid bilayer membrane particles or fragments thereof by measurement of the dye emission spectrum. The specific binding substance is conjugated to a magnetic bead or binds to a magnetic bead, the trapping and separating steps are performed magnetically, and the particle size of the magnetic bead is equal to or less than the minimum detection sensitivity of the measurement system.

Abstract: A vane wheel includes a shaft, an impeller, and a fixing member. The impeller includes an impeller cylinder portion into which one end portion of the shaft in an axial direction is inserted. The fixing member is disposed on one end side of the impeller cylinder portion in the axial direction and fixes the shaft and the impeller to each other. The shaft includes a step surface at the other end of the one end portion of the shaft in the axial direction. The other end surface of the impeller cylinder portion faces the step surface in the axial direction. The impeller includes a convex portion protruding in the axial direction on at least one of one end surface and the other end surface of the impeller cylinder portion in the axial direction. The convex portion is in contact with the fixing member or the step surface.

Abstract: A vane wheel includes a shaft and an impeller. The shaft is disposed along a center axis and is circular in plan view from an axial direction. The impeller includes an impeller cylinder portion to which one end portion of the shaft in the axial direction is fixed. The impeller cylinder portion includes a plurality of first portions and second portions on an inner circumferential surface of the impeller cylinder portion. The first portions are disposed with an interval in a circumferential direction, and are in contact with the shaft and fix the shaft. The second portions face the shaft with an interval in a radial direction, and each of the second portions is positioned between two of the first portions which are adjacent in the circumferential direction.

Abstract: Provided is a means by which a signal-to-noise ratio (S/N ratio) can be improved at the time of detection of lipid bilayer membrane particles (lipid vesicles) in which the amount of a surface antigen is small since the size of the particles is small and/or the amount of the particles existing in a sample is also small.

Abstract: Conventional CTC detection methods have been problematic in that 1) there is no technique for automatically determining and counting live CTCs in a brief period of time, 2) no process has been developed for detecting, counting, and thereafter collecting and culturing live CTCs, and 3) there exists no flow cytometer that is contamination free and is capable of measuring an entire sample. Provided is a CTC detection method which comprises a pre-treatment step for concentrating and fluorescence staining CTCs, and a step for identifying and counting CTCs. The pre-treatment step includes attaching magnetic beads to EpCAM antibodies expressed by epithelial cell-derived CTCs and concentrating the CTCs through the use of a magnet, fluorescently labeling an epithelia cell surface marker of the CTCs through the use of EpCAM antibodies or 5E11 antibodies, and performing two types of nuclear staining, one being cell membrane-permeable and the other being cell membrane-impermeable.

Abstract: Conventional CTC detection methods have been problematic in that 1) there is no technique for automatically determining and counting live CTCs in a brief period of time, 2) no process has been developed for detecting, counting, and thereafter collecting and culturing live CTCs, and 3) there exists no flow cytometer that is contamination free and is capable of measuring an entire sample. Provided is a CTC detection method which comprises a pre-treatment step for concentrating and fluorescence staining CTCs, and a step for identifying and counting CTCs. The pre-treatment step includes attaching magnetic beads to EpCAM antibodies expressed by epithelial cell-derived CTCs and concentrating the CTCs through the use of a magnet, fluorescently labeling an epithelia cell surface marker of the CTCs through the use of EpCAM antibodies or 5E11 antibodies, and performing two types of nuclear staining, one being cell membrane-permeable and the other being cell membrane-impermeable.

Abstract: Conventional CTC detection methods have been problematic in that 1) there is no technique for automatically determining and counting live CTCs in a brief period of time, 2) no process has been developed for detecting, counting, and thereafter collecting and culturing live CTCs, and 3) there exists no flow cytometer that is contamination free and is capable of measuring an entire sample. Provided is a CTC detection method which comprises a pre-treatment step for concentrating and fluorescence staining CTCs, and a step for identifying and counting CTCs. The pre-treatment step includes attaching magnetic beads to EpCAM antibodies expressed by epithelial cell-derived CTCs and concentrating the CTCs through the use of a magnet, fluorescently labeling an epithelia cell surface marker of the CTCs through the use of EpCAM antibodies or 5E11 antibodies, and performing two types of nuclear staining, one being cell membrane-permeable and the other being cell membrane-impermeable.

Abstract: An anti-EpCAM monoclonal antibody is provided which specifically recognizes an epitope different from the epitope which conventionally known anti-EpCAM monoclonal antibodies recognize (the N-terminal EGF-like domain). Also provided is a hybridoma which is capable of producing such monoclonal antibody, and a method for detecting CTC using such monoclonal antibody and a kit for detecting CTC, which is used for the method. The present application provides a monoclonal antibody to the human epithelial cell adhesion molecule (EpCAM) as a solution for the above problem, wherein the monoclonal antibody to the human epithelial cell adhesion molecule (EpCAM) specifically reacts with the CP region of the human epithelial cell adhesion molecule (EpCAM) and is produced by a hybridoma with accession No. NITE BP-1449.

Abstract: Conventional CTC detection methods have been problematic in that 1) there is no technique for automatically determining and counting live CTCs in a brief period of time, 2) no process has been developed for detecting, counting, and thereafter collecting and culturing live CTCs, and 3) there exists no flow cytometer that is contamination free and is capable of measuring an entire sample. Provided is a CTC detection method which comprises a pre-treatment step for concentrating and fluorescence staining CTCs, and a step for identifying and counting CTCs. The pre-treatment step includes attaching magnetic beads to EpCAM antibodies expressed by epithelial cell-derived CTCs and concentrating the CTCs through the use of a magnet, fluorescently labeling an epithelia cell surface marker of the CTCs through the use of EpCAM antibodies or 5E11 antibodies, and performing two types of nuclear staining, one being cell membrane-permeable and the other being cell membrane-impermeable.