Abstract: A particle separating and measuring device includes a first flow path device having a post-separation flow outlet to allow discharge of a first fluid containing target particles to be separated, and a second flow path device receiving the first flow path device and having a first flow inlet to receive the first fluid. The first flow path device having a lower surface having the post-separation flow outlet is on the second flow path device having an upper surface having the first flow inlet in a first region, with the post-separation flow outlet facing and connecting to the first flow inlet. A connection flow path vertically extends from an opening of the first flow inlet to a first flow path, and narrows from the opening of the first flow inlet toward the first flow path.

Abstract: A particle separation device comprises, inside a plate-like base body, a straight main flow path including a flow inlet and a plurality of branch flow paths. The flow inlet includes a sample flow inlet and a pressing flow inlet. The sample flow inlet is connected to the main flow path via a first bending part, a first straight part, a second bending part, and a second straight part. Widths in the first bending part and the first straight part are larger than widths in the second bending part and the second straight part. The widths in the second bending part and the second straight part are larger than a width in the main flow path. The pressing flow inlet is connected to the side surface of the main flow path via a third straight part, a third bending part, a fourth straight part, and a fifth straight part.

Abstract: A specimen introduction method for improving a measurement accuracy and efficiency includes a preparation step, first step, second step, and third step. The preparation step uses a switching member to connect a first feeder to a first inlet-and-outlet, a second inlet-and-outlet to a discharge container, a third inlet-and-outlet to a first inflow port, and a second feeder to a second inflow port. The first step includes filling a path from the second feeder to the switching member through the second inflow port, a specimen treatment device, and the first inflow port with a second liquid. The second step includes filling a path from the first feeder to the switching member with a first liquid. The third step includes subsequently introducing the first liquid into the first inflow port from the first feeder through the switching member, and introducing the second liquid into the second inflow port from the second feeder.

Abstract: A particle separating and measuring device of the present disclosure includes: a first flow path device including a post-separation flow outlet through which a first fluid containing specific particles to be separated flows out; and a second flow path device on which the first flow path device is placed and including a first flow inlet through which the first fluid flows in, the first flow path device in which the post-separation flow outlet is arranged in a lower surface is placed on the second flow path device in which the first flow inlet is arranged in an upper surface of a first region, the post-separation flow outlet and the first flow inlet are connected so as to face each other, and a size of an opening of the first flow inlet is larger than a size of an opening of the post-separation flow outlet.

Abstract: A flow path device comprises a plate-like measurement flow path device and a plate-like separation flow path device. The measurement flow path device includes a first flow path for measuring specific particles on a first fluid and connected to a third flow path and a second flow path for correction and passing a second fluid, not including the specific particles. The separation flow path device includes a fourth flow path for separating and selecting the specific particles from a sample and collecting a fluid. The separation flow path device is on the measurement flow path device's upper surface. The sample passes through a fifth flow path, the upper surface's opening, and flows into the fourth flow path from an opening in the separation flow path device's lower surface. The first fluid passes through the lower surface's opening, and flows into the first flow path from the upper surface's opening.

Abstract: A flow path device comprises a plate-like measurement flow path device and a plate-like separation flow path device. The measurement flow path device includes a first flow path for measuring specific particles on a first fluid and connected to a third flow path and a second flow path for correction and passing a second fluid, not including the specific particles. The separation flow path device includes a fourth flow path for separating and selecting the specific particles from a sample and collecting a fluid. The separation flow path device is on the measurement flow path device's upper surface. The sample passes through a fifth flow path, the upper surface's opening, and flows into the fourth flow path from an opening in the separation flow path device's lower surface. The first fluid passes through the lower surface's opening, and flows into the first flow path from the upper surface's opening.

Abstract: An inspection flow path device according to the present disclosure comprises: a first flow path device having a plate-like shape and including a pair of first surfaces located opposite to each other in a thickness direction and a first flow path located inside and including a first opening located in the pair of first surfaces and a branch flow path; and a second flow path device having a plate-like shape and translucency and including a pair of second surfaces located opposite to each other in a thickness direction and a second flow path located inside and including a second opening located in the pair of second surfaces; wherein one of the pair of first surfaces of the first flow path device is located on one of the pair of second surfaces of the second flow path device, and the first opening and the second opening are connected to each other.

Abstract: A particle measuring device has an upper surface having a first flow inlet to receive a first fluid containing target particles to be measured, a first flow path connected to the first flow inlet to allow measurement of the target particles, and a third flow path located upstream from and connected to a joint between the first flow path and the first flow inlet and having a smaller width than the first flow inlet. The first flow path includes a first planar portion having a greater width than the third flow path and the first flow inlet, a width-increasing portion located downstream from and connected to the first planar portion, and a second planar portion located downstream from and connected to the width-increasing portion.

Abstract: A particle separating and measuring device includes a first flow path device having a post-separation flow outlet to allow discharge of a first fluid containing target particles to be separated, and a second flow path device receiving the first flow path device and having a first flow inlet to receive the first fluid. The first flow path device having a lower surface having the post-separation flow outlet is on the second flow path device having an upper surface having the first flow inlet in a first region, with the post-separation flow outlet facing and connecting to the first flow inlet. A connection flow path vertically extends from an opening of the first flow inlet to a first flow path, and narrows from the opening of the first flow inlet toward the first flow path.

Abstract: A particle separating and measuring device includes a first flow path device having a post-separation flow outlet to allow discharge of a first fluid containing target particles to be separated, and a second flow path device receiving the first flow path device and having a first flow inlet to receive the first fluid. The first flow path device having a lower surface with the post-separation flow outlet is on the second flow path device having an upper surface with the first flow inlet in a first region. The post-separation flow outlet faces and connects to the first flow inlet. The first flow inlet has an opening larger than an opening of the post-separation flow outlet. The opening of the post-separation flow outlet connects to the opening of the first flow inlet at a peripheral portion of the opening of the first flow inlet.

Abstract: A measurement apparatus according to the present disclosure is a measurement apparatus capable of measuring particles in a fluid and comprises: a flow path device including a first flow path with translucency through which a first fluid including the particles passes and a second flow path with translucency through which a second fluid which does not include the particles passes; an optical sensor facing the flow path device, irradiating each of the first flow path and the second flow path with light, and receiving light passing through each of the first flow path and the second flow path; and a controller measuring the particles by comparing an intensity of light passing through the first flow path and an intensity of light passing through the second flow path, each of which is obtained by the optical sensor.

Abstract: A particle separating and measuring device of the present disclosure includes: a first flow path device including a post-separation flow outlet through which a first fluid containing specific particles to be separated flows out; and a second flow path device on which the first flow path device is placed and including a first flow inlet through which the first fluid flows in, the first flow path device in which the post-separation flow outlet is arranged in a lower surface is placed on the second flow path device in which the first flow inlet is arranged in an upper surface of a first region, the post-separation flow outlet and the first flow inlet are connected so as to face each other, and a size of an opening of the first flow inlet is larger than a size of an opening of the post-separation flow outlet.

Abstract: A specimen introduction method of the present disclosure includes: a preparation step of, by using a switching member, connecting a first feeder to a first inlet-and-outlet, connecting a second inlet-and-outlet to a discharge container, and connecting a third inlet-and-outlet to a first inflow port, and further connecting a second feeder to a second inflow port; a first step of filling a path from the second feeder to the switching member through the second inflow port, a specimen treatment device, and the first inflow port with a second liquid; a second step of filling a path from the first feeder to the switching member with a first liquid; and a third step of subsequently introducing the first liquid into the first inflow port from the first feeder through the switching member, and introducing the second liquid into the second inflow port from the second feeder.

Abstract: A particle separation device comprises, inside a plate-like base body, a straight main flow path including a flow inlet and a plurality of branch flow paths. The flow inlet includes a sample flow inlet and a pressing flow inlet. The sample flow inlet is connected to the main flow path via a first bending part, a first straight part, a second bending part, and a second straight part. Widths in the first bending part and the first straight part are larger than widths in the second bending part and the second straight part. The widths in the second bending part and the second straight part are larger than a width in the main flow path. The pressing flow inlet is connected to the side surface of the main flow path via a third straight part, a third bending part, a fourth straight part, and a fifth straight part.

Abstract: A flow path device includes: a first substrate having a pair of first main surfaces, a groove and a first recessed portion; and a second substrate having a pair of second main surfaces. The groove includes an opening located in one of the pair of first main surfaces. The first recessed portion includes another opening located in another one of the pair of first main surfaces and overlaps the groove. One of the pair of second main surfaces is located on a side of the one of the pair of first main surfaces to cover the opening of the groove. The groove is a band-like shape, and includes a first planar part and a second planar part connected to the first planar part. The second planar part has a width larger than the first planar part. The first recessed portion overlaps the second planar part.

Abstract: A measurement apparatus according to the present disclosure is a measurement apparatus capable of measuring particles in a fluid and comprises: a flow path device including a first flow path with translucency through which a first fluid including the particles passes and a second flow path with translucency through which a second fluid which does not include the particles passes; an optical sensor facing the flow path device, irradiating each of the first flow path and the second flow path with light, and receiving light passing through each of the first flow path and the second flow path; and a controller measuring the particles by comparing an intensity of light passing through the first flow path and an intensity of light passing through the second flow path, each of which is obtained by the optical sensor.