Patents by Inventor Masashiro Funaki

Masashiro Funaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carbonyl reductase, gene thereof and method of using the same
    Patent number: 7915022
    Abstract: The present invention relates to a polypeptide having an activity to asymmetrically reduce (3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanone to produce (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol isolated from a microorganism belonging to the genus Ogataea, a DNA encoding the polypeptide and a transformant that produces the polypeptide. The present invention moreover relates to a method of producing (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol utilizing the polypeptide or the transformant. Using the polypeptide or transformant of the present invention, optically active alcohols such as (2R,3S)-1-chloro-3-tert-butoxycarbonylamino-4-phenyl-2-butanol and the like can be produced efficiently.
    Type: Grant
    Filed: July 20, 2010
    Date of Patent: March 29, 2011
    Assignee: Kaneka Corporation
    Inventors: Noriyuki Kizaki, Miho Yano, Masashiro Funaki, Teruaki Takesue, Yoshihiko Yasohara, Souichi Morikawa, Takahisa Nakai, Michihiko Kataoka, Sakayu Shimizu