Patents by Inventor Masataka Katsuma
Masataka Katsuma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9050249Abstract: The present invention relates to an oral pharmaceutical composition in particle form, which comprises particles that contain a drug at the core of the pharmaceutical composition in particle form; a middle layer that contains two types of water-soluble components, an insolubilizer and an insolubilizing substance; and an outer layer for controlling water penetration that contains a water-insoluble substance. The present invention makes it possible to provide a pharmaceutical composition in particle form for oral use with which initial drug release is suppressed, the drug is quickly released thereafter, and lag time can be controlled as needed, and fast-disintegrating tablets containing this composition.Type: GrantFiled: April 28, 2005Date of Patent: June 9, 2015Assignee: ASTELLAS PHARMA INC.Inventors: Takayuki Yoshida, Hiroaki Tasaki, Masataka Katsuma, Atsushi Maeda
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Publication number: 20050287211Abstract: The present invention relates to an oral pharmaceutical composition in particle form, which comprises particles that contain a drug at the core of the pharmaceutical composition in particle form; a middle layer that contains two types of water-soluble components, an insolubilizer and an insolubilizing substance; and an outer layer for controlling water penetration that contains a water-insoluble substance. The present invention makes it possible to provide a pharmaceutical composition in particle form for oral use with which initial drug release is suppressed, the drug is quickly released thereafter, and lag time can be controlled as needed, and fast-disintegrating tablets containing this composition.Type: ApplicationFiled: April 28, 2005Publication date: December 29, 2005Applicant: Astellas Pharma Inc.Inventors: Takayuki Yoshida, Hiroaki Tasaki, Masataka Katsuma, Atsushi Maeda
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Publication number: 20050181031Abstract: The transdermal permeable property of solifenacin or a salt thereof as a biologically active substance, is remarkably improved using a fatty acid ester, a terpene or the like as a selected transdermal permeable promoter. The difference in effect exceeded expectations by producing an enhancement in permeability that represents an increase of several hundredfold at most, and several tenfold for practical application, enabling the provision of extremely useful means for preventive and therapeutic agents for urologic diseases or respiratory diseases that use solifenacin.Type: ApplicationFiled: February 18, 2005Publication date: August 18, 2005Inventors: Katsumi Saito, Masataka Katsuma
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Publication number: 20050175689Abstract: The present invention makes it possible to provide drug-containing coated microparticles for quick-disintegrating oral tablets wherein microparticles containing a drug with an unpleasant taste are coated with a film composed of (1) a pH-independent water-insoluble polymer accounting for 60% or more but less than 80% of the film and (2) a pH-independent water-soluble substance accounting for more than 20% to 40% or less of the film, these microparticles being characterized in that the rate of dissolution of the drug from the drug-containing microparticles is 0% to 10% in one minute and 80% to 100% in 30 minutes, and the average particle diameter is 350 ?m or less, in order to realize sufficient control of oral drug dissolution and fast gastrointestinal drug dissolution.Type: ApplicationFiled: October 27, 2004Publication date: August 11, 2005Applicant: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Ippei Kurimoto, Yuki Kasashima, Hitoshi Kawai, Yuuki Takaishi, Masataka Katsuma, Hiroshi Ohi, Takayuki Yoshida, Hiroaki Tasaki
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Patent number: 6919372Abstract: The present invention relates to sustained-release pharmaceutical compositions for ionic pharmaceutically active substances containing ionic compounds having opposite charges to those of ionic prostanoic acid derivatives and increasing hydrophobicity of the active substances. More specifically, the invention relates to sustained-release pharmaceutical compositions comprising the ionic prostanoic acid derivatives and the ionic compounds having opposite charges to those of the prostanoic acid derivatives and increasing hydrophobicity of these derivatives that contain hydrophobic groups in the molecule thereof. The pharmaceutical composition of the invention can exhibit excellent sustained release effect of the ionic prostanoic acid derivatives, irrespective of water solubility possessed by the ionic prostanoic acid derivatives.Type: GrantFiled: December 25, 1998Date of Patent: July 19, 2005Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Noboru Yamashita, Akira Takagi, Masataka Katsuma, Katsumi Saito, Yuuki Takaishi, Tatsuo Yasuda, Yutaka Takahashi, Mitsuo Mitomi, Michio Hara
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Publication number: 20040184995Abstract: The present invention provides marked results in that it is possible to present by a simple method a dry powder inhalation for pulmonary delivery that is made from a biologically active substance in crystal form and a biocompatible, electrostatic aggregation-inhibiting substance and that has excellent safety, stability, and pulmonary delivery performance.Type: ApplicationFiled: March 17, 2003Publication date: September 23, 2004Applicant: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Masataka Katsuma, Hitoshi Kawai, Takao Mizumoto
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Patent number: 6506407Abstract: A system for releasing a drug specifically in the colon of the gastrointestinal tract, which comprises a drug (b) coated with an organic acid-soluble polymer material (a), and a saccharide (c) which rapidly generates an organic acid by the action of enterobacteria in the lower part of the gastrointestinal tract; a colon-specific drug release oral preparation, which comprises a composition comprising a drug (b) coated with an organic acid-soluble polymer material (a) and a saccharide (c) which rapidly generates an organic acid by the action of enterobacteria in the lower part of the gastrointestinal tract, said composition being coated with an enteric coating polymer material (d). The invention provides a drug release system and a preparation which utilize enterobacteria, which do not form harmful substances due to the release-starting mechanism, show rapid degradation, and have higher colon specificity.Type: GrantFiled: September 14, 2001Date of Patent: January 14, 2003Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Shunsuke Watanabe, Hitoshi Kawai, Masataka Katsuma, Muneo Fukui
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Publication number: 20020044975Abstract: A system for releasing a drug specifically in the colon of the gastrointestinal tract, which comprises a drug (b) coated with an organic acid-soluble polymer material (a), and a saccharide (c) which rapidly generates an organic acid by the action of enterobacteria in the lower part of the gastrointestinal tract; a colon-specific drug release oral preparation, which comprises a composition comprising a drug (b) coated with an organic acid-soluble polymer material (a) and a saccharide (c) which rapidly generates an organic acid by the action of enterobacteria in the lower part of the gastrointestinal tract, said composition being coated with an enteric coating polymer material (d).Type: ApplicationFiled: September 14, 2001Publication date: April 18, 2002Inventors: Shunsuke Watanabe, Hitoshi Kawai, Masataka Katsuma, Muneo Fukui
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Patent number: 6368629Abstract: A system for releasing a drug specifically in the colon of the gastrointestinal tract, which comprises a drug (b) coated with an organic acid-soluble polymer material (a), and a saccharide (c) which rapidly generates an organic acid by the action of enterobacteria in the lower part of the gastrointestinal tract; a colon-specific drug release oral preparation, which comprises a composition comprising a drug (b) coated with an organic acid-soluble polymer material (a) and a saccharide (c) which rapidly generates an organic acid by the action of enterobacteria in the lower part of the gastrointestinal tract, said composition being coated with an enteric coating polymer material (d). The invention provides a drug release system and a preparation which utilize enterobacteria, which do not form harmful substances due to the release-starting mechanism, show rapid degradation, and have higher colon specificity.Type: GrantFiled: October 30, 1998Date of Patent: April 9, 2002Assignee: Yamanouchi Pharmaceutical Company Ltd.Inventors: Shunsuke Watanabe, Hitoshi Kawai, Masataka Katsuma, Muneo Fukui
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Patent number: 6328979Abstract: The present invention relates to sustained-release pharmaceutical compositions for ionic pharmaceutically active substances (excluding ionic prostanoic acid derivatives) containing ionic compounds having opposite charges to those of the active substances and increasing hydrophobicity of the active substances. More specifically, the invention relates to sustained-release pharmaceutical compositions comprising the ionic pharmaceutically active substances and the ionic compounds having opposite charges to those of the active substances and increasing hydrophobicity of the active substances that contain hydrophobic groups in the molecule thereof. The pharmaceutical composition of the invention can exhibit excellent sustained release effect of the active substance, irrespective of water solubility possessed by the ionic pharmaceutically active substances.Type: GrantFiled: June 23, 2000Date of Patent: December 11, 2001Assignee: Yamanouchi Pharmaceuticals, Co. Ltd.Inventors: Noboru Yamashita, Akira Takagi, Masataka Katsuma, Katsumi Saito, Yuuki Takaishi, Tatsuo Yasuda, Yutaka Takahashi, Mitsuo Mitomi