Abstract: In order to provide a novel determination device capable of determining the type of excretion by a subject and a related technology thereof, a determination device includes at least one processor, and the at least one processor carries out a determination process of determining the type of excretion by a subject by referring to a first gas concentration, which is a gas concentration detected by a first gas sensor, and a second gas concentration, which is a gas concentration detected by a second gas sensor that is disposed at a position farther from the subject than a position at which the first gas sensor is disposed.

Abstract: In order to provide a novel determination device capable of determining the type of excretion by a subject and a related technology thereof, a determination device includes at least one processor, and the at least one processor carries out a determination process of determining the type of excretion by a subject by referring to a first gas concentration detected by a first gas sensor and a second gas concentration detected by a second gas sensor which differs from the first gas sensor in gas species to be mainly detected.

Abstract: The present disclosure concerns combination therapy for cancer that utilizes (i) an oncolytic virus; (ii) a virus comprising nucleic acid encoding an immunomodulatory factor; and (iii) at least one cell comprising a chimeric antigen receptor (CAR) specific for a cancer cell antigen. In particular embodiments, the virus comprises nucleic acid encoding an immunomodulatory factor comprises nucleic acid encoding IL-12 and/or antagonist anti-PD-L1 antibody.

Abstract: An apparatus includes a supporting base arranged to support a panel arranged to detect incident radiation, a power supply including a positive terminal portion and a negative terminal portion, a substrate connected to the positive terminal portion and the negative terminal portion, an insulating sheet arranged between the supporting base, and the power supply and the substrate, wherein the power supply and the substrate are fixed to the insulating sheet, and a sheet fixing member arranged to fix at least one sheet end of a plurality of sheet ends of the insulating sheet to the supporting base.

Abstract: An apparatus includes a supporting base arranged to support a panel arranged to detect incident radiation, a power supply including a positive terminal portion and a negative terminal portion, a substrate connected to the positive terminal portion and the negative terminal portion, an insulating sheet arranged between the supporting base, and the power supply and the substrate, wherein the power supply and the substrate are fixed to the insulating sheet, and a sheet fixing member arranged to fix at least one sheet end of a plurality of sheet ends of the insulating sheet to the supporting base.

Abstract: A surgery assisting device that includes one or more joint portions and that holds a surgical instrument, and a computing device that obtains angle information of a joint portion of the one or more joint portions in a state in which a distal end of the surgical instrument is positioned at a predetermined position and determines a length of the surgical instrument based on the angle information.

Abstract: According to one aspect of the present invention, a data management device creates a shared storage area accessible only by the first user and the second user. The data management device further generates a new data file as shared data of the first user and the second user by extracting, according to a shared use condition of data for the second user that is set by the first user, at least some data of at least one data file among one or more data files of the first user, said one or more data files being stored in a dedicated storage area isolated from the second user. Further, the data management device stores the generated shared data in the shared storage area.

Abstract: A communication control apparatus according to one aspect of the present invention determines whether a message to be transmitted from an information processing apparatus include at least one attached file, when the message is transmitted from the information processing apparatus to one or more destinations via a network. When the communication control apparatus has determined that the message to be transmitted includes said at least one attached file, the communication control apparatus acquires approval of transmission of said at least one attached file from an approver, and transmits the message including said at least one attached file to said one or more destinations, on condition that approval of transmission of said at least one attached file has been received from the approver.

Abstract: A communication control apparatus according to an aspect of the present invention downloads and acquires, from a center server on a cloud, an approval rule by an approver of upload in upload of a data file to the center server. The approval rule is stored in the center server. When any data file is uploaded to the center server, the communication control apparatus acquires approval of upload of the any data file from the approver in accordance with the acquired approval rule, and uploads the data file to the center server on condition that approval of upload of the data file has been acquired from the approver.

Abstract: A radiographing apparatus includes a support base and a housing. The support base includes a base side protruding portion that protrudes towards a bottom surface of the housing. The housing includes a housing side protruding portion that protrudes in a direction toward the support base. A first gap and a second gap are formed between the base side protruding portion and the housing side protruding portion in a perpendicular direction with respect to an incident direction of radiation at different positions. The first gap and the second gap are different from each other in distance in the perpendicular direction between the base side protruding portion and the housing side protruding portion.

Abstract: A medical operation apparatus includes a body graspable by an operator, an operation part that is arranged to enable a part of the operation part to be moved relative to the body, and a holder that receives the fingers of the operator and transmits a movement of the fingers to the operation part. The holder includes a contact portion that comes in contact with the body, and a connector that supports a relative posture of the holder and the operation part so as to change the relative posture in accordance with a posture change of the fingers of the operator. In a relative arrangement position of the operation part and the body, when the relative posture of the holder and the operation part is changed, an amount of change in the relative arrangement position of the body and the operation part is within a specified permissible range.

Abstract: The confidentiality of data is maintained in a case where analysis of an operation state of a facility is entrusted to the outside. Time difference information in operation between the manufacturing apparatuses (RB1), (RB2), . . . , arranged on the production line (LN) is stored for each of the apparatuses, in an inter-apparatus time difference information storage unit (33). At the occurrence of a failure in one of the manufacturing apparatuses (RB1), (RB2), . . . , the operation estimation unit (13) selects, from among the peripheral apparatuses on the upstream side and the downstream side with respect to the manufacturing apparatus concerned, one on the upstream side and one on the downstream side, estimates an operation period of each selected peripheral apparatus associated with the failure, reads log data corresponding to the estimated operation period from the operation history storage unit (31), and transmits the read piece to the external support center (SC).

Abstract: The confidentiality of data is maintained in the case of outsourcing analysis of an operation state of a facility. Degree-of-relevance information indicating a degree of relevance in operation between a plurality of apparatuses included in a facility is stored. At the occurrence of a failure in a first apparatus included in the plurality of apparatuses, a second apparatus having a degree of relevance in operation to the first apparatus equal to or greater than a preset first threshold is selected from the plurality of apparatuses based on the degree-of-relevance information, and the log data relating to operation states of the first apparatus in which a failure has occurred and the selected second apparatus are selectively read from a first memory storage, and the read log data is transmitted to a data user via a network.

Abstract: The confidentiality of data is maintained in a case where analysis of an operation state of a facility is entrusted to the outside. An embodiment of the present invention is configured to chronologically store log data in a first storage medium, and store attribute information indicating a relevance between a type of a failure expected to occur in a facility and each of a plurality of data users; The embodiment is further configured to select, at the occurrence of a failure in the facility, a data user who has a relevance to a type of the failure from among the plurality of data users based on the attribute information, selectively read log data relating to an operation state of the facility in which the failure has occurred, and transmits the read log data to the selected data user.

Abstract: A surgery-assisting device includes a robot arm that includes plural movable bodies that are operably connected in order in a connecting direction, a surgical instrument connected to a distal end of the robot arm, and one or more actuators that generate a driving force that operates one or more of the movable bodies. The movable bodies include one or more distal-side movable bodies that is provided distally in the connection direction, and one or more proximal-side movable bodies that is provided proximally in the connection direction. An operation tolerance of the one or more distal-side movable bodies is higher than an operation tolerance of the one or more proximal-side movable bodies.

Abstract: The present disclosure concerns combination therapy for cancer thatutilizes (i) an oncolytic virus; (ii) a virus comprising nucleic acid encoding an immunomodulatory factor; and (iii) at least one cell comprising a chimeric antigen receptor (CAR) specific for a cancer cell antigen. In particular embodiments, the virus comprises nucleic acid encoding an immunomodulatory factor comprises nucleic acid encoding IL-12 and/or antagonist anti-PD-L1 antibody.

Abstract: A mechanism that enhances rigidity of a casing of a radiation imaging apparatus while effectively using limited space inside the casing is provided. The rectangular casing that contains a radiation detecting panel, the radiation detecting panel detecting incident radiation, includes a front cover including an incident surface on which the radiation is incident, and a rear cover disposed in a manner to be opposite to the front cover. The rear cover includes one or more recess portions and a rib, at least one end of the rib being connected to a recess portion of the one or more recess portions, at a bottom surface opposite to the incident surface.

Abstract: Methods of treating a cancer, comprising administering to a subject: (i) a virus comprising nucleic acid encoding an antigen-binding molecule comprising: (a) an antigen-binding moiety specific for an immune cell surface molecule, and (b) an antigen-binding moiety specific for a cancer cell antigen; and (ii) an oncolytic virus, and/or (iii) at least one cell comprising a chimeric antigen receptor (CAR) specific for a cancer cell antigen are disclosed. Also disclosed are articles and compositions for use in such methods.

Abstract: In a radiation imaging apparatus, a first recessed portion is formed in at least one side surface among a plurality of side surfaces forming a frame body of a casing. Moreover, a second recessed portion is formed in a peripheral region of a back surface of a back-surface housing, which is a region opposite to the first recessed portion with respect to a boundary between the back surface and the at least one side surface of the casing including the first recessed portion.

Abstract: A surgery assisting device holds a surgical instrument having an end to be inserted into a body cavity of a patient, and controls one or more of a position or an orientation of the surgical instrument. The surgery assisting device includes a first arm and second arms. The first arm has a first end supported by a base and includes a first movable part having movement with one or more degrees of freedom. The second arms are arranged at a second end of the first arm and hold the surgical instrument. Each of the second arms includes second movable parts having movement with five or more degrees of freedom.