Patents by Inventor Masatake Fujimura

Masatake Fujimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dihydropyrazolopyridine compounds and pharmaceutical use thereof
    Patent number: 6977262
    Abstract: The present invention provides dihydropyrazolopyridine compounds represented by the formula (I): wherein each symbol is as defined in the specification, optically active forms thereof, and pharmaceutically acceptable salts thereof and hydrates thereof. The compounds of the present invention show a selective and strong inhibitory activity on glycogen synthase kinase-3 beta (GSK-3?), and are useful as medicaments for prevention and/or treatment of diabetes, diabetic complications and neurodegenerative diseases or as immunopotentiators.
    Type: Grant
    Filed: August 1, 2003
    Date of Patent: December 20, 2005
    Assignee: Mitsubishi Pharma Corporation
    Inventors: Toshiyuki Kohara, Kenji Fukunaga, Masatake Fujimura, Tokushi Hanano, Hirotaka Okabe
  • Dihydropyrazolopyridine compounds and pharmaceutical use thereof
    Publication number: 20040052822
    Abstract: The present invention provides dihydropyrazolopyridine compounds represented by the formula (I): 1
    Type: Application
    Filed: August 1, 2003
    Publication date: March 18, 2004
    Inventors: Toshiyuki Kohara, Kenji Fukunaga, Masatake Fujimura, Tokushi Hanano, Hirotaka Okabe
  • Condensed thiophene compounds and pharmaceutical use thereof
    Patent number: 6455521
    Abstract: A condensed thiophene compound of the formula (I) wherein each symbol is as defined in the specification, a pharmaceutically acceptable salt thereof and hydrates thereof. The compound of the formula (I) of the present invention is useful as a novel antipsychotic agent which is effective for both positive symptoms and negative symptoms of schizophrenia, which is associated with less side effects such as extrapyramidal motor disorder and the like and which is less associated with serious side effects such as agranulocytosis and the like. In addition, this compound is also useful as a therapeutic agent of Alzheimer's disease and manic-depressive illness.
    Type: Grant
    Filed: April 19, 2001
    Date of Patent: September 24, 2002
    Assignee: Mitsubishi Pharma Corporation
    Inventors: Koji Seio, Hiroshi Tanaka, Toshiyuki Kohara, Kenji Hashimoto, Masatake Fujimura, Hideki Horiuchi, Hiroshi Yasumatsu, Koreichi Kimura
  • Condensed thiophene compounds and pharmaceutical use thereof
    Publication number: 20020042411
    Abstract: A condensed thiophene compound of the formula (I) 1
    Type: Application
    Filed: April 19, 2001
    Publication date: April 11, 2002
    Inventors: Koji Seio, Hiroshi Tanaka, Toshiyuki Kohara, Kenji Hashimoto, Masatake Fujimura, Hideki Horiuchi, Hiroshi Yasumatsu, Koreichi Kimura
  • Fused thiophene compounds and medicinal use thereof
    Patent number: 6271225
    Abstract: A condensed thiophene compound of the formula (I) wherein each symbol is as defined in the specification, a pharmaceutically acceptable salt thereof and hydrates thereof. The compound of the formula (I) of the present invention is useful as a novel antipsychotic agent which is effective for both positive symptoms and negative symptoms of schizophrenia, which is associated with less side effects such as extrapyramidal motor disorder and the like and which is less associated with serious side effects such as agranulocytosis and the like. In addition, this compound is also useful as a therapeutic agent of Alzheimer's disease and manic-depressive illness.
    Type: Grant
    Filed: July 8, 1999
    Date of Patent: August 7, 2001
    Assignee: Welfide Corporation
    Inventors: Koji Seio, Hiroshi Tanaka, Toshiyuki Kohara, Kenji Hashimoto, Masatake Fujimura, Hideki Horiuchi, Hiroshi Yasumatsu, Koreichi Kimura