Patents by Inventor Masateru Hoshino

Masateru Hoshino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression vector encoding a triterpene hydroxylase polypeptide
    Patent number: 7575892
    Abstract: Soyasapogenol B is biosynthesized via two steps of hydroxylation reaction of its precursor ?-amyrin. However, the gene of the hydroxylase concerned in this reaction has not been revealed. Therefore, it was impossible to apply a genetic engineering technique on the hydroxylase. The present inventors reveals that a sequence which corresponds to a soybean-derived cytochrome P-450 gene CYP93E1 encodes an enzyme protein that carries out hydroxylation of the 24-position of an oleanane type triterpene, and also provides a method for applying said gene making use of a genetic engineering technique.
    Type: Grant
    Filed: February 25, 2005
    Date of Patent: August 18, 2009
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Hiroaki Hayashi, Kenichiro Inoue, Masateru Hoshino, Masaaki Shibuya, Yutaka Ebizuka
  • Triterpene Hydroxylase
    Publication number: 20080003639
    Abstract: Soyasapogenol B is biosynthesized via two steps of hydroxylation reaction of its precursor ?-amyrin. However, the gene of the hydroxylase concerned in this reaction has not been revealed. Therefore, it was impossible to apply a genetic engineering technique on the hydroxylase. The present inventors reveals that a sequence which corresponds to a soybean-derived cytochrome P-450 gene CYP93E1 encodes an enzyme protein that carries out hydroxylation of the 24-position of an oleanane type triterpene, and also provides a method for applying said gene making use of a genetic engineering technique.
    Type: Application
    Filed: February 25, 2005
    Publication date: January 3, 2008
    Inventors: Hiroaki Hayashi, Kenichiro Inoue, Masateru Hoshino, Masaaki Shibuya, Yutaka Ebizuka