Abstract: A biological material extraction magnetic bead contains: a magnetic metal powder; an inorganic oxide layer that covers a particle surface of the magnetic metal powder and contains an inorganic oxide; a base layer that covers a surface of the inorganic oxide layer and contains a gold ion reducing agent or a catalyst for a gold ion reduction reaction; a gold layer that covers a surface of the base layer and contains gold; and an immobilization layer that is bonded to a surface of the gold layer via an Au—S bond and contains a compound having a ligand or a ligand binding site.

Abstract: A composition for aqueous ink contains water and a coloring material, wherein the calcium ion content x (ppm) and the oxalate ion content y (ppm) in the composition for aqueous ink jet satisfy the relation of y?3491.8x?3.386.

Abstract: A composition for aqueous ink jet contains a specific dye which is one or more coloring materials selected from the group consisting of C. I. Acid Black 172 and C. I. Acid Black 194, and a specific aromatic compound which is at least one compound selected from the group consisting of compounds represented by formulae (1) to (4) below. The content of the specific aromatic compound relative to 100 parts by mass of the specific dye is 0.2 parts by mass or more and 50 parts by mass or less.

Abstract: A biological material extraction carrier includes a magnetic bead including a magnetic metal powder and a first coating layer that coats a particle surface of the magnetic metal powder and that is made of a first oxide material, and an oxide powder, in which a particle surface is made of a second oxide material, and an average particle diameter is smaller than that of the magnetic bead. Further, the average particle diameter of the magnetic bead is preferably 0.5 ?m or more and 50 ?m or less.

Abstract: A dispensing device that dispenses a liquid sample with a target weight x (in grams) includes: a pipette that discharges the liquid sample into a vessel; and a controller that controls the pipette. The controller performs: first liquid discharge processing in which the controller discharges the liquid sample with a volume of (x/?0×y) milliliters (mL) into the pipette, where y is a numeric value greater than 0 and smaller than 1, and ?0 is the tentative density (in grams per mL) of the liquid sample; first weight acquisition processing in which the controller acquires information about the weight z (in grams) of the liquid sample discharged in first liquid discharge processing; density calculation processing in which the controller calculates the density p (in grams/mL) of the liquid sample according to the expression ?=z/(x/?0×y); and second liquid discharge processing in which the controller discharges, into the pipette, the liquid sample with a volume based on the density ?, weight z, and target weight x.

Abstract: A magnetic bead reagent contains: a magnetic bead containing a Fe-based metal soft magnetic particle and a silica film that has an average thickness of 20 nm or more and that covers the Fe-based metal soft magnetic particle; a surfactant; and a dispersion medium in which the magnetic bead is dispersed. The surfactant may be a nonionic surfactant.

Abstract: A magnetic bead separation method includes: storing, in a container, a mixed liquid containing a magnetic bead and a liquid containing target molecules, and adsorbing the target molecules on the magnetic bead, the magnetic bead containing a Fe-based metal soft magnetic particle and a coating film with which the Fe-based metal soft magnetic particle is coated, and having a saturation magnetization of 50 emu/g or more and 250 emu/g or less; applying an external magnetic field to the container and magnetically attracting at least a part of the magnetic bead by the external magnetic field; and applying an acceleration to the container while the magnetic bead is magnetically attracted by the external magnetic field and desorbing the liquid adhering to the magnetic bead.

Abstract: A powder suction and discharge apparatus including a pipe, a container that is coupled to the pipe, a valve that opens and closes a passage of the pipe, and a pressure reducing mechanism that causes an internal space of the container to have negative pressure, in which in a first state in which the valve is open and the pressure reducing mechanism is driven, powder is sucked into the container through the pipe, in a second state in which the valve is closed, the sucked powder is stored in the container, and in a third state in which the valve is open, the stored powder is discharged through the pipe.

Abstract: A purification apparatus includes a holding unit including a bottom plate for supporting a bottom portion of a container to be mounted, and a magnetic unit arranged on the bottom plate or below the bottom plate so as to face the bottom portion of the container. The magnetic unit fixes magnetic particles of an amorphous metal to an inner bottom portion or an inner wall of the container so as to separate a liquid in the container and the magnetic particles contained in the liquid from each other and/or to collect the liquid while leaving the magnetic particles in the container.

Abstract: An ink jet textile printing ink contains 5% by mass to 20% by mass of a water-soluble dye, water, a water-soluble organic solvent, and active carbon particles. The active carbon particles include particles having a particle size of 50 nm to 1000 nm, and the active carbon particles having the particle size of 50 nm to 1000 nm are contained in a proportion of 500 to 300000 particles per milliliter. Also, the active carbon particles may include particles having a particle size of 50 nm to 200 nm, and the active carbon particles having a particle size of 50 nm to 200 nm may be contained in a proportion of 2000 to 30000 particles per milliliter. The active carbon particles may have an average particle size in the range of 100 nm to 600 nm.

Abstract: A composition for aqueous ink jet contains a specific dye which is one or more coloring materials selected from the group consisting of C. I. Acid Black 172 and C. I. Acid Black 194, and a specific aromatic compound which is at least one compound selected from the group consisting of compounds represented by formulae (1) to (4) below. The content of the specific aromatic compound relative to 100 parts by mass of the specific dye is 0.2 parts by mass or more and 50 parts by mass or less.

Abstract: A composition for aqueous ink contains water and a coloring material, wherein the calcium ion content x (ppm) and the oxalate ion content y (ppm) in the composition for aqueous ink jet satisfy the relation of y?3491.8x?3.386.

Abstract: An ink jet textile printing ink contains 5% by mass to 20% by mass of a water-soluble dye, water, a water-soluble organic solvent, and active carbon particles. The active carbon particles include particles having a particle size of 50 nm to 1000 nm, and the active carbon particles having the particle size of 50 nm to 1000 nm are contained in a proportion of 500 to 300000 particles per milliliter. Also, the active carbon particles may include particles having a particle size of 50 nm to 200 nm, and the active carbon particles having a particle size of 50 nm to 200 nm may be contained in a proportion of 2000 to 30000 particles per milliliter. The active carbon particles may have an average particle size in the range of 100 nm to 600 nm.

Abstract: A nucleic acid amplification reaction method includes a thermal cycling step of performing thermal cycling for amplifying a nucleic acid for a reaction solution containing a primer, a temperature increasing step of increasing the temperature of the reaction solution to a temperature at which the amplified nucleic acid is denatured after the thermal cycling step, a temperature decreasing step of decreasing the temperature of the reaction solution to a temperature at which a probe hybridizes after the temperature increasing step, and a probe addition step of adding the probe to the reaction solution.

Abstract: A nucleic acid amplification reaction method includes performing thermal cycling for amplifying a nucleic acid for a reaction solution containing a primer and a probe, wherein in the thermal cycling, the time per cycle of the thermal cycling is 9 seconds or less, and the Tm value of the primer is 70° C. or higher and 80° C. or lower.

Abstract: A nucleic acid amplification reaction method includes performing thermal cycling for amplifying a nucleic acid for a reaction solution containing a template nucleic acid, a primer, a probe, and a polymerase, wherein in the thermal cycling, the time per cycle of the thermal cycling is 9 seconds or less, the calculated Tm value of the primer is 65° C. or higher and 80° C. or lower, a ?Tm value obtained by subtracting the actually measured Tm value of the primer from the actually measured Tm value of the probe is ?11° C. or more and 2° C. or less, the calculated Tm value is a value calculated according to a calculation formula, and the actually measured Tm value is an actually measured value obtained by actual measurement.

Abstract: A nucleic acid amplification reaction method includes a heating step of heating a reaction solution containing a reverse transcriptase, a polymerase, a primer, and a probe for performing a reverse transcription reaction, and a thermal cycling step of performing thermal cycling for amplifying a nucleic acid for the reaction solution after the heating step, wherein the Tm value of the primer is 65° C. or higher and 80° C. or lower, and in the heating step, a heating time for the reaction solution is 5 seconds or more and 480 seconds or less.

Abstract: The object of the present invention is to provide a method to obtain an antibody for a hydrophobic peptide, which can be used for general purposes easily and with great reliability. Also provided is a method for preparing an antigen characterized in that a hydrophobic peptide, which is unbound to carrier protein, is used as high-molecular-weight aggregates in an aqueous solution containing a nonionic surfactant.

Abstract: A nucleic acid extraction device includes a tube part in which a first plug of an oil, a second plug of a cleansing liquid not miscible with the oil for cleansing a material with adsorbed nucleic acid, a third plug of an oil, a fourth plug of an eluate not miscible with the oil for eluting nucleic acid from the material, and a fifth plug of an oil are provided in this order, and a cover part provided to surround the tube part.

Abstract: A nucleic acid amplification reaction apparatus includes: a fitting section capable of fitting a reaction vessel filled with a reaction mixture and a liquid which has a specific gravity different from that of the reaction mixture and is immiscible with the reaction mixture; a first heating section which heats a first region of the reaction vessel; a second heating section which heats a second region of the reaction vessel; and a driving mechanism which switches over between a first arrangement in which the first region is located lower than the second region in the direction of the gravitational force and a second arrangement in which the second region is located lower than the first region in the direction of the gravitational force, wherein the concentration of magnesium ions in the reaction mixture is 1.8 mM or more and 9.0 mM or less.