Patents by Inventor Masato Horie

Masato Horie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030143688
    Abstract: The present invention provides novel human genes, for example a novel human gene comprising a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:1. The use of the genes makes it possible to detect the expression of the same in various tissues, analyze their structures and functions, and produce the human proteins encoded by the genes by the technology of genetic engineering. Through these, it becomes possible to analyze the corresponding expression products, elucidate the pathology of diseases associated with the genes, for example hereditary diseases and cancer, and diagnose and treat such diseases.
    Type: Application
    Filed: January 15, 2003
    Publication date: July 31, 2003
    Applicant: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Tsutomu Fujiwara, Takeshi Watanabe, Masato Horie
  • Patent number: 6562947
    Abstract: An isolated and purified human skeletal muscle-specific ubiquitin-conjugating enzyme comprising the amino acid sequence shown in SEQ ID NO:22 is disclosed. The use of the genes makes it possible to detect the expression of the same in various tissues, analyze their structures and functions, and produce the human proteins encoded by the genes by the technology of genetic engineering. Through these, it becomes possible to analyze the corresponding expression products, elucidate the pathology of diseases associated with the genes, for example hereditary diseases and cancer, and diagnose and treat such diseases.
    Type: Grant
    Filed: October 15, 2001
    Date of Patent: May 13, 2003
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Tsutomu Fujiwara, Takeshi Watanabe, Masato Horie
  • Publication number: 20020151025
    Abstract: This invention provides the TSC403 gene having a nucleotide sequence coding for the amino acid sequence of SEQ ID NO:1, which is a novel gene of great utility particularly in the field of research, diagnosis, therapy, etc. for cancer of the lung, among other diseases.
    Type: Application
    Filed: April 5, 2002
    Publication date: October 17, 2002
    Inventors: Masami Nagata, Kouichi Ozaki, Yoshikazu Shimada, Masato Horie
  • Publication number: 20020107383
    Abstract: The present invention provides novel human genes, for example a novel human gene comprising a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:1. The use of the genes makes it possible to detect the expression of the same in various tissues, analyze their structures and functions, and produce the human proteins encoded by the genes by the technology of genetic engineering. Through these, it becomes possible to analyze the corresponding expression products, elucidate the pathology of diseases associated with the genes, for example hereditary diseases and cancer, and diagnose and treat such diseases.
    Type: Application
    Filed: October 15, 2001
    Publication date: August 8, 2002
    Inventors: Tsutomu Fujiwara, Takeshi Watanabe, Masato Horie
  • Patent number: 6403785
    Abstract: This invention provides the TSC403 gene having a nucleotide sequence coding for the amino acid sequence of SEQ ID NO:1, which is a novel gene of great utility particularly in the field of research, diagnosis, therapy, etc. for cancer of the lung, among other diseases. In addition, this invention provides the human ING1L gene comprising a nucleotide sequence coding for the amino acid sequence of SEQ ID NO:4, which is a novel human gene useful for regulating the cell cycle, inhibiting or activating cell proliferation, studies on metabolic aging or apoptosis of cells, pathological exploration, diagnosis and therapy of cancer and other diseases, and screening for the development of new drugs.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: June 11, 2002
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Masami Nagata, Kouichi Ozaki, Yoshikazu Shimada, Masato Horie
  • Publication number: 20020058624
    Abstract: A method is disclosed for stabilizing a physiologically active peptide in a process of preparing a powder containing the physiologically active peptide by drying an aqueous liquid containing the physiologically active peptide, wherein the method comprises adding to the aqueous liquid at least one compound selected from the group consisting of a nonionic surfactant, a water-soluble, nonionic, organic binder, hydrogenated lecithin, and mannitol.
    Type: Application
    Filed: November 28, 2001
    Publication date: May 16, 2002
    Applicant: JCR PHARMACEUTICALS CO., Lrd.
    Inventors: Yoshinobu Hanyu, Mariko Okada, Chihiro Shindo, Satoshi Nishimuro, Tetsuo Yokoyama, Masato Horie
  • Publication number: 20020009789
    Abstract: A method is disclosed for stabilizing a physiologically active peptide in a process of preparing a powder containing the physiologically active peptide by drying an aqueous liquid containing the physiologically active peptide, wherein the method comprises adding to the aqueous liquid at least one compound selected from the group consisting of a nonionic surfactant, a water-soluble, nonionic, organic binder, hydrogenated lecithin, and mannitol.
    Type: Application
    Filed: March 19, 2001
    Publication date: January 24, 2002
    Applicant: JCR PHARMACEUTICALS CO., Ltd.
    Inventors: Yoshinobu Hanyu, Mariko Okada, Chihiro Shindo, Satoshi Nishimuro, Tetsuo Yokoyama, Masato Horie
  • Patent number: 6333404
    Abstract: The present invention provides novel human genes, for example a novel human gene comprising a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:1. The use of the genes makes it possible to detect the expression of the same in various tissues, analyze their structures and functions, and produce the human proteins encoded by the genes by the technology of genetic engineering. Through these, it becomes possible to analyze the corresponding expression products, elucidate the pathology of diseases associated with the genes, for example hereditary diseases and cancer, and diagnose and treat such diseases.
    Type: Grant
    Filed: May 5, 2000
    Date of Patent: December 25, 2001
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Tsutomu Fujiwara, Takeshi Watanabe, Masato Horie
  • Patent number: 6005088
    Abstract: The present invention provides novel human genes, for example a novel human gene comprising a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO: 1. The use of the genes makes it possible to detect the expression of the same in various tissues, analyze their structures and functions, and produce the human proteins encoded by the genes by the technology of genetic engineering. Through these, it becomes possible to analyze the corresponding expression products, elucidate the pathology of diseases associated with the genes, for example hereditary diseases and cancer, and diagnose and treat such diseases.
    Type: Grant
    Filed: April 7, 1998
    Date of Patent: December 21, 1999
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Tsutomu Fujiwara, Takeshi Watanabe, Masato Horie
  • Patent number: 5831058
    Abstract: The present invention provides novel human genes, for example a novel human gene comprising a nucleotide sequence coding for the amino acid sequence shown under SEQ ID NO:1. The use of the genes makes it possible to detect the expression of the same in various tissues, analyze their structures and functions, and produce the human proteins encoded by the genes by the technology of genetic engineering. Through these, it becomes possible to analyze the corresponding expression products, elucidate the pathology of diseases associated with the genes, for example hereditary diseases and cancer, and diagnose and treat such diseases.
    Type: Grant
    Filed: March 19, 1997
    Date of Patent: November 3, 1998
    Assignee: Otsuka Pharmaceutical Co., Ltd.
    Inventors: Tsutomu Fujiwara, Takeshi Watanabe, Masato Horie