Patents by Inventor Masato Ishizawa
Masato Ishizawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11415589Abstract: Provided is an automatic analyzer provided with a liquid level sensing function in which liquid levels in sample containers having various heights can be precisely detected using ultrasonic waves. This device is provided with: a conveyance rack for conveying a sample container which contains a sample and is loaded thereon; a fixed ultrasonic distance sensor for measuring the liquid level position in the sample container loaded on the conveyance rack; sound wave guides for suppressing diffusion of sound waves transmitted from the ultrasonic distance sensor, the sound wave guides being disposed between the sample container and the ultrasonic distance sensor; and a sound wave guide control unit for adjusting the length or switching the length of the sound wave guides in accordance with the distance between the ultrasonic distance sensor and the sample container.Type: GrantFiled: December 26, 2018Date of Patent: August 16, 2022Assignee: Hitachi High-Tech CorporationInventors: Yosuke Horie, Yasuhiro Yoshimura, Atsushi Kazama, Masato Ishizawa, Satoru Yamamoto
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Patent number: 11389838Abstract: An ultrasonic cleaner according to the present invention includes a vibrating part 222 for enlarging ultrasonic vibration of a bolt-clamped Langevin type transducer (BLT) 100 on a side surface side in a cleaning tank 211, generates cavitation by the ultrasonic vibration with respect to cleaning liquid supplied into the cleaning tank 211 by driving the BLT 100 on the periphery of a nozzle without unevenness, and is capable of performing effective nozzle cleaning.Type: GrantFiled: August 27, 2020Date of Patent: July 19, 2022Assignee: Hitachi High-Tech CorporationInventors: Yosuke Horie, Tomohiro Inoue, Takamichi Mori, Kouhei Nonaka, Masato Ishizawa, Isao Yamazaki, Hitoshi Tokieda, Akihiro Nojima
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Patent number: 11327088Abstract: A reagent-bottle lid opening mechanism is disclosed, which has a needle for piercing a lid of a reagent bottle to be delivered to a reagent disk, has an aligning mechanism of automatically adjusting a position of the needle with respect to the lid such that a needle body of the needle can stick in the center of the lid, and accurately and repeatedly makes an incision in the center of the lid. As a result, an automatic analyzer is provided that is capable of unsealing the center of the lid of the reagent bottle with accuracy even if the central axis of the needle and the central axis of the lid are offset from each other.Type: GrantFiled: January 13, 2017Date of Patent: May 10, 2022Assignee: Hitachi High-Tech CorporationInventors: Masaki Hara, Takamichi Mori, Masato Ishizawa
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Patent number: 11237182Abstract: To clean a reagent probe 7a, 8a or a sample probe 11a, 12a with a heated cleaning solution, after a first cleaning solution is caused to overflow from a first cleaning container 23 or a second cleaning container 24, the first cleaning solution is temporarily drawn back into the cleaning-solution heating passage 125 to be heated by the heating mechanism 123. After the heating, the first cleaning solution thus heated is re-supplied to the first cleaning container 23 or the second cleaning container 24. As a result, the cleaning solution heated to clean a dispensing probe can be supplied to a cleaning bath with efficiency.Type: GrantFiled: January 23, 2017Date of Patent: February 1, 2022Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Kohei Nonaka, Takamichi Mori, Masato Ishizawa
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Patent number: 11199559Abstract: An automatic analyzer with high processing capacity is capable of immediately measuring an emergency specimen rack. The automatic analyzer includes a conveying line for conveying a specimen rack, and an analysis unit which has a dispensing line in which a plurality of specimen racks are arranged for waiting until sample dispensing, and a sampling area for dispensing the sample to the analysis unit. A rack save area is provided in the dispensing line and at a position adjacent to the upstream side of the sampling area. When a specimen rack exists in the sampling area at the time of measuring an emergency specimen rack, a controller moves the specimen rack to the save area and positions the emergency specimen rack to be moved from a downstream side of the sampling area to the sampling area.Type: GrantFiled: October 29, 2019Date of Patent: December 14, 2021Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Akihisa Makino, Mitsuhiro Hishinuma, Toshiyuki Shimamori, Masato Ishizawa
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Patent number: 11175301Abstract: An automatic analyzer includes: a reagent mounting unit 103 in which a plurality of reagent bottles 10 are installed when a reagent bottle 10 is loaded into the automatic analyzer; a reagent conveying mechanism 101 including a gripper mechanism 106; and a reagent mounting mechanism 102 for moving the reagent mounting unit 103 between an installation position at which an operator installs the reagent bottle 10 in the reagent mounting unit 103 and a position at which the gripper mechanism 106 grips the reagent bottle 10. It is thereby possible to achieve saving of a mechanism installation space and reduction of the number of constituent components, automatically carry out an operation from opening of the reagent bottle to loading of the reagent bottle into the reagent disk, and alleviate an operator's burden.Type: GrantFiled: August 23, 2016Date of Patent: November 16, 2021Assignees: HITACHI HIGH-TECH CORPORATION, ROCHE DIAGNOSTICS OPERATIONS, INC.Inventors: Takamichi Mori, Kouhei Nonaka, Masaki Hara, Masato Ishizawa, Hitoshi Tokieda, Stephan Sattler
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Publication number: 20210096148Abstract: Provided is an automatic analyzer provided with a liquid level sensing function in which liquid levels in sample containers having various heights can be precisely detected using ultrasonic waves. This device is provided with: a conveyance rack for conveying a sample container which contains a sample and is loaded thereon; a fixed ultrasonic distance sensor for measuring the liquid level position in the sample container loaded on the conveyance rack; sound wave guides for suppressing diffusion of sound waves transmitted from the ultrasonic distance sensor, the sound wave guides being disposed between the sample container and the ultrasonic distance sensor; and a sound wave guide control unit for adjusting the length or switching the length of the sound wave guides in accordance with the distance between the ultrasonic distance sensor and the sample container.Type: ApplicationFiled: December 26, 2018Publication date: April 1, 2021Inventors: Yosuke HORIE, Yasuhiro YOSHIMURA, Atsushi KAZAMA, Masato ISHIZAWA, Satoru YAMAMOTO
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Publication number: 20210053094Abstract: An ultrasonic cleaner according to the present invention includes a vibrating part 222 for enlarging ultrasonic vibration of a bolt-clamped Langevin type transducer (BLT) 100 on a side surface side in a cleaning tank 211, generates cavitation by the ultrasonic vibration with respect to cleaning liquid supplied into the cleaning tank 211 by driving the BLT 100 on the periphery of a nozzle without unevenness, and is capable of performing effective nozzle cleaning.Type: ApplicationFiled: August 27, 2020Publication date: February 25, 2021Inventors: Yosuke HORIE, Tomohiro INOUE, Takamichi MORI, Kouhei NONAKA, Masato ISHIZAWA, Isao YAMAZAKI, Hitoshi TOKIEDA, Akihiro NOJIMA
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Patent number: 10786835Abstract: An ultrasonic cleaner according to the present invention includes a vibrating part 222 for enlarging ultrasonic vibration of a BLT 100 on a side surface side in a cleaning tank 211, generates cavitation by the ultrasonic vibration with respect to cleaning liquid supplied into the cleaning tank 211 by driving the BLT 100 on the periphery of a nozzle without unevenness, and is capable of performing effective nozzle cleaning.Type: GrantFiled: June 27, 2016Date of Patent: September 29, 2020Assignee: HITACHI HIGH-TECH CORPORATIONInventors: Yosuke Horie, Tomohiro Inoue, Takamichi Mori, Kouhei Nonaka, Masato Ishizawa, Isao Yamazaki, Hitoshi Tokieda, Akihiro Nojima
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Publication number: 20200064365Abstract: An automatic analyzer with high processing capacity is capable of immediately measuring an emergency specimen rack. The automatic analyzer includes a conveying line for conveying a specimen rack, and an analysis unit which has a dispensing line in which a plurality of specimen racks are arranged for waiting until sample dispensing, and a sampling area for dispensing the sample to the analysis unit. A rack save area is provided in the dispensing line and at a position adjacent to the upstream side of the sampling area. When a specimen rack exists in the sampling area at the time of measuring an emergency specimen rack, a controller moves the specimen rack to the save area and positions the emergency specimen rack to be moved from a downstream side of the sampling area to the sampling area.Type: ApplicationFiled: October 29, 2019Publication date: February 27, 2020Inventors: Akihisa MAKINO, Mitsuhiro HISHINUMA, Toshiyuki SHIMAMORI, Masato ISHIZAWA
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Patent number: 10512915Abstract: A nucleic acid amplifier comprises a holder 3 which is provided with a plurality of temperature control blocks 10 each designed to hold at least one reaction vessel 105 storing a reaction solution. The temperature of the reaction solution in each reaction vessel 105 is controlled individually by using temperature control devices 14 and 15 arranged in each of the temperature control blocks 10. The temperature that is set in each temperature control block 10 and the timing for temperature changes are controlled independently of the temperatures of other temperature control blocks 10. This configuration makes it possible to provide a nucleic acid amplifier and a nucleic acid inspection device (employing the nucleic acid amplifier) capable of processing multiple types of samples differing in the protocol in parallel (parallel processing) and starting a process for a different sample even when there is a process in execution.Type: GrantFiled: April 28, 2011Date of Patent: December 24, 2019Assignee: Hitachi High-Technologies CorporationInventors: Minoru Sano, Yoshiyuki Shoji, Masato Ishizawa, Kimikazu Sugiyama
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Patent number: 10495658Abstract: An automatic analyzer with high processing capacity is capable of immediately measuring an emergency specimen rack. The automatic analyzer includes a conveying line for conveying a specimen rack, and an analysis unit which has a dispensing line in which a plurality of specimen racks are arranged for waiting until sample dispensing, and a sampling area for dispensing the sample to the analysis unit. A rack save area is provided in the dispensing line and at a position adjacent to the upstream side of the sampling area. When a specimen rack exists in the sampling area at the time of measuring an emergency specimen rack, a controller moves the specimen rack to the save area and positions the emergency specimen rack to be moved from a downstream side of the sampling area to the sampling area.Type: GrantFiled: March 23, 2017Date of Patent: December 3, 2019Assignee: Hitachi High-Technologies CorporationInventors: Akihisa Makino, Mitsuhiro Hishinuma, Toshiyuki Shimamori, Masato Ishizawa
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Patent number: 10330692Abstract: The purpose of the present invention is to provide an automatic analysis device that combines a biochemical analysis unit and a blood coagulation analysis unit and has a high processing capacity while reducing device cost and life-cycle cost. An automatic analysis device is characterized in that when a synthetic-substrate item or latex-agglutination item from among synthetic-substrate, latex-agglutination, and clotting-time blood-coagulation-test items is made to be a first test item and the clotting-time item is made to be a second test item, if there is a measurement request for the first test item and second test item in the same specimen rack, a control unit determines the conveyance path of the specimen rack such that the first test item is measured using a biochemical analysis unit and the second test item is measured using a coagulation time analysis unit and controls a conveyance line.Type: GrantFiled: November 5, 2014Date of Patent: June 25, 2019Assignee: Hitachi High-Technologies CorporationInventors: Akihisa Makino, Chie Yabutani, Masato Ishizawa
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Publication number: 20190041415Abstract: To clean a reagent probe 7a, 8a or a sample probe 11a, 12a with a heated cleaning solution, after a first cleaning solution is caused to overflow from a first cleaning container 23 or a second cleaning container 24, the first cleaning solution is temporarily drawn back into the cleaning-solution heating passage 125 to be heated by the heating mechanism 123. After the heating, the first cleaning solution thus heated is re-supplied to the first cleaning container 23 or the second cleaning container 24. As a result, the cleaning solution heated to clean a dispensing probe can be supplied to a cleaning bath with efficiency.Type: ApplicationFiled: January 23, 2017Publication date: February 7, 2019Inventors: Kohei NONAKA, Takamichi MORI, Masato ISHIZAWA
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Publication number: 20190018033Abstract: A reagent-bottle lid opening mechanism is disclosed, which has a needle for piercing a lid of a reagent bottle to be delivered to a reagent disk, has an aligning mechanism of automatically adjusting a position of the needle with respect to the lid such that a needle body of the needle can stick in the center of the lid, and accurately and repeatedly makes an incision in the center of the lid. As a result, an automatic analyzer is provided that is capable of unsealing the center of the lid of the reagent bottle with accuracy even if the central axis of the needle and the central axis of the lid are offset from each other.Type: ApplicationFiled: January 13, 2017Publication date: January 17, 2019Inventors: Masaki HARA, Takamichi MORI, Masato ISHIZAWA
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Publication number: 20180246132Abstract: An automatic analyzer includes: a reagent mounting unit 103 in which a plurality of reagent bottles 10 are installed when a reagent bottle 10 is loaded into the automatic analyzer; a reagent conveying mechanism 101 including a gripper mechanism 106; and a reagent mounting mechanism 102 for moving the reagent mounting unit 103 between an installation position at which an operator installs the reagent bottle 10 in the reagent mounting unit 103 and a position at which the gripper mechanism 106 grips the reagent bottle 10. It is thereby possible to achieve saving of a mechanism installation space and reduction of the number of constituent components, automatically carry out an operation from opening of the reagent bottle to loading of the reagent bottle into the reagent disk, and alleviate an operator's burden.Type: ApplicationFiled: August 23, 2016Publication date: August 30, 2018Inventors: Takamichi MORI, Kouhei NONAKA, Masaki HARA, Masato ISHIZAWA, Hitoshi TOKIEDA, Stephan SATTLER
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Publication number: 20180161829Abstract: An ultrasonic cleaner according to the present invention includes a vibrating part 222 for enlarging ultrasonic vibration of a BLT 100 on a side surface side in a cleaning tank 211, generates cavitation by the ultrasonic vibration with respect to cleaning liquid supplied into the cleaning tank 211 by driving the BLT 100 on the periphery of a nozzle without unevenness, and is capable of performing effective nozzle cleaning.Type: ApplicationFiled: June 27, 2016Publication date: June 14, 2018Inventors: Yosuke HORIE, Tomohiro INOUE, Takamichi MORI, Kouhei NONAKA, Masato ISHIZAWA, Isao YAMAZAKI, Hitoshi TOKIEDA, Akihiro NOJIMA
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Patent number: 9970948Abstract: If an air bubble is entrained when a reagent is added to a sample, disturbance caused by this air bubble may prevent accurate optical measurement, thereby reducing accuracy for measuring blood clotting ability. The position to dispense the reagent depends on accuracy of stopping a reagent dispensing mechanism and dimensional errors of individual detectors, and thus conventional reagent discharging method may entrain an air bubble because a distance between a nozzle for dispensing the reagent and an inner wall of a reaction vessel is not constant and conditions for dispensing the reagent to the sample vary. In the present invention, an automatic analyzer with a nozzle for sucking and discharging the reagent for blood clotting reaction is provided with a dispensing mechanism that keeps a constant position for the nozzle to discharge the reagent by pressing the nozzle against the inner wall of the reaction vessel within the elastic range.Type: GrantFiled: October 22, 2014Date of Patent: May 15, 2018Assignee: Hitachi High-Technologies CorporationInventors: Toshiyuki Shimamori, Akihisa Makino, Masato Ishizawa
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Patent number: 9714455Abstract: A device for detecting nucleic acid amplification in a sample, comprising: a loading unit (thermoregulation unit) which is provided with a plurality of holes for loading reaction containers and capable of arbitrarily controlling a measurement unit for measuring samples in the containers that are loaded in the holes. The loading unit and the measurement unit, which are placed opposite to each other, can be operated independently from each other. In a transfer operation, the operation speeds of the thermoregulation unit and measurement unit are controlled so that the sum of these speeds amounts to an arbitrary constant value.Type: GrantFiled: July 4, 2011Date of Patent: July 25, 2017Assignee: Hitachi High-Technologies CorporationInventors: Kimikazu Sugiyama, Masato Ishizawa, Yoshiyuki Shoji, Minoru Sano
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Patent number: 9709588Abstract: An automatic analyzer with high processing capacity is capable of immediately measuring an emergency specimen rack. The automatic analyzer includes a conveying line for conveying a specimen rack, and an analysis unit which has a dispensing line in which a plurality of specimen racks are arranged for waiting until sample dispensing, and a sampling area for dispensing the sample to the analysis unit. A rack save area is provided in the dispensing line and at a position adjacent to the upstream side of the sampling area. When a specimen rack exists in the sampling area at the time of measuring an emergency specimen rack, a controller moves the specimen rack to the save area and positions the emergency specimen rack to be moved from a downstream side of the sampling area to the sampling area.Type: GrantFiled: May 19, 2014Date of Patent: July 18, 2017Assignee: Hitachi High-Technologies CorporationInventors: Akihisa Makino, Mitsuhiro Hishinuma, Toshiyuki Shimamori, Masato Ishizawa