Publication number: 20190345154
Abstract: The present invention provides a novel 2,4,6-substituted pyrimidine derivative, which is a compound represented by formula (I) (in the formula, ring A is a 6-membered heteroaryl group having at least one N atom optionally substituted with R1, R2, and R3; Z is an optionally substituted alkoxy group, an optionally substituted amino group, an optionally substituted heterocycloalkyl group, or an optionally substituted heteroaryl group; and R1, R2, and R3 are each independently selected from the group consisting of a hydrogen atom, a halogen atom, an optionally substituted alkyl group, an optionally substituted cycloalkyl group, an optionally substituted alkoxy group, an optionally substituted cycloalkyloxy group, an optionally substituted heterocycloalkyloxy group, an optionally substituted phenoxy group, an optionally substituted amino group, a nitro group, and a hydroxy group) or a pharmaceutically acceptable salt thereof.
Type:
Application
Filed:
October 25, 2017
Publication date:
November 14, 2019
Applicants:
CARNA BIOSCIENCES, INC., THE KITASATO INSTITUTE
Inventors:
Masaaki SAWA, Yuko ASAMITSU, Yuko UNO, Satoshi OMURA, Kazuhiko OTOGURO, Masato IWATSUKI, Aki ISHIYAMA, Rei HOKARI