Abstract: A first node apparatus includes: ports; a storage device; and receiving, updating, and transmitting circuits. The storage device stores: information associating, with first identification information identifying a first frame, information distinguishing a first port having been used as a destination port when the first node apparatus has transmitted the first frame; and information associating, with each node apparatus, state information indicating whether frame transmission from each port is feasible. The receiving circuit receives, from a second node apparatus, a second frame including second identification information. When the second identification information is identical with the first, the updating circuit updates the state information associated with a node apparatus being a destination of the second frame to make the state information indicate frame transmission from the first port is not feasible.

Abstract: A bearing seal includes: a ring-shaped outer seal portion; a ring-shaped inner seal portion provided inside the outer seal portion; a connecting portion for connecting the inner seal portion and the outer seal portion; and a ring-shaped rigid portion provided at the connecting portion. The outer seal portion, the inner seal portion, and the connecting portion are integrally formed of the same material consisting of an elastic material. The inner seal portion has rigidity higher than that of the outer seal portion, and has a ring-shaped seal surface gradually approaching a ring center axis of the inner seal portion while extending from a ring-shaped base end side connected to the connecting portion toward a distal end side. The inner seal portion is formed in a tapered cylindrical shape having the ring-shaped seal surface on an inner peripheral surface thereof, and has a thickness which gradually decreases from the base end side toward the distal end side.

Abstract: It is intended to provide a method and system for carrying out data production with respect to the actual status of cells as a profile. It is also intended to provide a system and method for presenting time-lapse and/or real-time information of cell interior directly, or as it is, from the viewpoint of a complex system. It is further intended to provide a method of presenting a digital cell. Thus, there is provided a method of producing profile data relating to cell information, comprising the step (a) of arranging cells in an immobilized form on a support and the step (b) of monitoring over time biological factors on or inside the cells or an aggregate thereof, thereby producing profile data for the cells. Furthermore, there is provided a method of producing a digital cell, comprising procuring experimental data by the use of the above method.

Abstract: The present invention provides a double-stranded RNA which inhibits replication of influenza B viruses by RNA interference, in which the double-stranded RNA comprises an RNA having 19 to 25 nucleotides homologous with a part of an mRNA transcribed from a genomic RNA of the influenza B viruses and an antisense RNA thereof.

Abstract: A reconfigurable circuit is provided, which includes a first arithmetic unit that performs addition or subtraction of a first input data and a second input data and outputs output data, and a first selector that selects an output data of the first arithmetic unit or a third input data and outputs the selected one as the first input data to the first arithmetic unit.

Abstract: The present invention provides a method for deriving an upstream or downstream component of a component necessary for phenotypic alteration of a living organism, the method comprising the steps of: specifying a pathway of interest related to the phenotypic alteration and a reference pathway different from the pathway of interest, and specifying a stimulant of interest and a reference stimulant which respectively stimulate the pathway of interest and the reference pathway; giving the stimulant of interest to the living organism to identify a collection of components of interest necessary for the phenotypic alteration; giving the reference stimulant to the living organism to identify a collection of reference components necessary for the phenotypic alteration; calculating an intersection between the collections of the components of interest and the reference components; and calculating a differential collection by subtracting the intersection from the collection of components of interest.

Abstract: It is intended to provide a method and system for carrying out data production with respect to the actual status of cells as a profile. It is also intended to provide a system and method for presenting time-lapse and/or real-time information of cell interior directly, or as it is, from the viewpoint of a complex system. It is further intended to provide a method of presenting a digital cell. Thus, there is provided a method of producing profile data relating to cell information, comprising the step (a) of arranging cells in an immobilized form on a support and the step (b) of monitoring over time biological factors on or inside the cells or an aggregate thereof, thereby producing profile data for the cells. Furthermore, there is provided a method of producing a digital cell, comprising procuring experimental data by the use of the above method.

Abstract: The present invention provides a method capable of improving the efficiency of introducing a target substance (e.g., DNA, polypeptides, sugars, or complexes thereof), which is difficult to introduce (particularly, transfect) into a cell in any circumstances. Particularly, the present invention provides a composition for increasing the efficiency of introducing a target substance into a cell, comprising (a) an actin acting substance. The present invention also provides a device and method using such a composition.

Abstract: The present invention provides a programmable logic device including a main circuit unit capable of variably building desired user logic, based on configuration data inputted from a storage device, and a configuration data monitor unit for monitoring configuration data stored in the storage device.

Abstract: In an inexpensive and convenient method for immobilizing a suspension cell, a phospholipid vesicle or the like regardless of the type of cell, on the surface of a solid phase, a cell is immobilized by causing the cell to contact a support having a hydrophobic chain and a hydrophilic chain.

Abstract: A digital cell database and means for making network analysis using the database and actual data. A method for creating a database of digital cells and a device concerning the method are provided. A method for providing a service to reproduce an experiment according to a parameter to be analyzed on the basis of the results of an experiment on an actual cell using a digital cell by means of a computer system including a service requester and a service provider are also provided. The technique is solved by providing a support through which cells can be arranged in the same environment.

Abstract: There is provided a tool for effectively performing a meaningful analysis of a system state by using a specific index. A part having unusual behavior is extracted as an event timing from time-series data on an index derived from a system. An event descriptor describing the state of the system by using the event timing is generated. A method for generating the event descriptor associated with at least one system includes: a step (A) for acquiring time-series data on at least one index derived from at least one system; a step (B) for providing at least one peculiar behavior associated with the index; and a step (C) for extracting a part having the peculiar behavior as an event timing in the time-series data and generating an event descriptor described by the event timing.

Abstract: The present invention provides a method for deriving an upstream or downstream component of a component necessary for phenotypic alteration of a living organism, the method comprising the steps of: specifying a pathway of interest related to the phenotypic alteration and a reference pathway different from the pathway of interest, and specifying a stimulant of interest and a reference stimulant which respectively stimulate the pathway of interest and the reference pathway; giving the stimulant of interest to the living organism to identify a collection of components of interest necessary for the phenotypic alteration; giving the reference stimulant to the living organism to identify a collection of reference components necessary for the phenotypic alteration; calculating an intersection between the collections of the components of interest and the reference components; and calculating a differential collection by subtracting the intersection from the collection of components of interest.

Abstract: It is an object of the present invention to provide a bearing seal not only whose sealing performance is favorable in normal time, but also whose sealing performance can be prevented from being deteriorated when subjected to vibration caused by impact. A bearing seal includes: a ring-shaped outer seal portion 51; a ring-shaped inner seal portion 52 provided inside the outer seal portion 51; a connecting portion 53 for connecting the inner seal portion 52 and the outer seal portion 51; and an inner ring 60 provided at the connecting portion 53. The outer seal portion 51, the inner seal portion 52, and the connecting portion 53 are integrally formed of the same material consisting of an elastic material.

Abstract: It is intended to provide a method whereby transfer efficiency can be improved under any conditions in the case of transferring (in particular, transfecting) a target substance that cannot easily be transferred into cells (for example, a DNA, a polypeptide, a sugar, a complex thereof or the like). Namely, a composition for elevating the transfer efficiency of a target substance into cells which contains a cell adhesion-related factor, and a device and a method using the composition.

Abstract: A reconfigurable circuit is provided, which includes a first arithmetic unit that performs addition or subtraction of a first input data and a second input data and outputs output data, and a first selector that selects an output data of the first arithmetic unit or a third input data and outputs the selected one as the first input data to the first arithmetic unit.

Abstract: The present invention provides a method and system for analyzing a network of biological functions, such as transcriptional factors, structural genes, cellular markers, cell surface markers, cell shapes, organelle shapes, cell mobility, enzyme activities, metabolite concentrations, and localization of cellular components, in a biological entity such as a cell. Particularly, an object of the present invention is to provide a system and method for presenting biological information in a global manner without modification where the cell is considered a complex system.

Abstract: A chemical sensor utilizing a chemical receptor (for example, one stimulating the sense of taste or smell) is provided. More specifically speaking, such a receptor is introduced into cells and the cells are immobilized on a support to form a chip. This chip is then employed as a component of a sensor. This sensor shows a reaction almost the same as the body's perception of the taste or smell or sense, thereby enabling analysis. Thus, it is also usable as an artificial sensory organ. Moreover, this sensor is usable in diagnosis, which imparts a high industrial usefulness to it.

Abstract: It is intended to provide a method and system for carrying out data production with respect to the actual status of cells as a profile. It is also intended to provide a system and method for presenting time-lapse and/or real-time information of cell interior directly, or as it is, from the viewpoint of a complex system. It is further intended to provide a method of presenting a digital cell. Thus, there is provided a method of producing profile data relating to cell information, comprising the step (a) of arranging cells in an immobilized form on a support and the step (b) of monitoring over time biological factors on or inside the cells or an aggregate thereof, thereby producing profile data for the cells. Furthermore, there is provided a method of producing a digital cell, comprising procuring experimental data by the use of the above method.

Abstract: The present invention provides a programmable logic device including a main circuit unit capable of variably building desired user logic, based on configuration data inputted from a storage device, and a configuration data monitor unit for monitoring configuration data stored in the storage device.