Abstract: A radiation detection apparatus includes a first sensor panel that generates a signal in accordance with incident radiation, a second sensor panel that generates a signal in accordance with incident radiation, and an adhesive member that couples together the first sensor panel and the second sensor panel. When a stimulation is applied to the adhesive member, an adhesive force of the adhesive member is lowered to a strength at which the first sensor panel and the second sensor panel can be separated without causing damage.

Abstract: The present invention provides an optical film having a liquid crystal layer having excellent durability, and a liquid crystal film. The optical film of the present invention has an organic base material and a liquid crystal layer disposed on the organic base material, the liquid crystal layer contains a photo-alignment compound, and in the liquid crystal layer, the photo-alignment compound is unevenly distributed on a side of the organic base material.

Abstract: The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases. The present disclosure relates to a compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof.

Abstract: Provided is a tire puncture sealant having excellent puncture seal durability. The present disclosure relates to a puncture sealant containing at least one natural rubber latex, at least one antioxidant, at least one antifreezing agent, and at least one selected from the group consisting of protease inhibitors and phosphatase inhibitors.

Abstract: The present disclosure relates to a non-transitory computer-readable recording medium storing an analysis program that causes a computer to execute a process. The process includes sampling an instruction address of one of instructions included in a program during execution of the program, identifying a first function that includes the sampled instruction address in an address range, rewriting mark information associated with the identified first function, identifying first information corresponding to the instruction address of the first function among a plurality of first information based on the rewritten mark information, identifying second information corresponding to the instruction address of the first function among a plurality of second information based on the rewritten mark information, storing the first information and the second information in a memory, and analyzing performance of the program based on the first information and the second information stored in the memory.

Abstract: A manufacturing device manufactures a bearing unit including an inner ring member outwardly fitted onto an end portion of a shaft main body of an inner shaft on one side in an axial direction and fixed by a swaged portion extending from the end portion. The manufacturing device includes: a rotating mechanism including a rotor which holds the other side of the inner shaft in the axial direction from below and rotates the inner shaft about a center axis of the inner shaft while the center axis is aligned with an up-down direction, the rotor being mounted below a processing area of the bearing unit; and a swaging mechanism mounted above the processing area and including a punch which is brought into contact with the swaged portion to plastically deform the swaged portion.

Abstract: A manufacturing device manufactures a bearing unit including an inner ring member outwardly fitted onto an end portion of a shaft main body of an inner shaft on one side in an axial direction and fixed by a swaged portion extending from the end portion. The manufacturing device includes: a rotating mechanism including a rotor which holds the other side of the inner shaft in the axial direction from below and rotates the inner shaft about a center axis of the inner shaft while the center axis is aligned with an up-down direction, the rotor being mounted below a processing area of the bearing unit; and a swaging mechanism mounted above the processing area and including a punch which is brought into contact with the swaged portion to plastically deform the swaged portion.

Abstract: The present disclosure relates to a non-transitory computer-readable recording medium storing an analysis program that causes a computer to execute a process. The process includes sampling an instruction address of one of instructions included in a program during execution of the program, identifying a first function that includes the sampled instruction address in an address range, rewriting mark information associated with the identified first function, identifying first information corresponding to the instruction address of the first function among a plurality of first information based on the rewritten mark information, identifying second information corresponding to the instruction address of the first function among a plurality of second information based on the rewritten mark information, storing the first information and the second information in a memory, and analyzing performance of the program based on the first information and the second information stored in the memory.

Abstract: Provided is a tire puncture sealant having excellent puncture seal durability. The present disclosure relates to a puncture sealant containing at least one natural rubber latex, at least one antioxidant, at least one antifreezing agent, and at least one selected from the group consisting of protease inhibitors and phosphatase inhibitors.

Abstract: A recombinant vector for producing an induced pluripotent stem cell, including an Oct family gene, a Klf family gene, and a Myc family gene, wherein the genes are inserted in the vector and an induced pluripotent stem cell including the recombinant vector. Also disclosed is a method for preparing a recombinant vector for producing an induced pluripotent stem cell, including inserting each of the three genes into a vector such that the genes are capable of expression. Also disclosed are a first recombinant vector for preparing a second recombinant vector for producing an induced pluripotent stem cell, said first recombinant vector including at least two of the following four genes: an Oct family gene, a Klf family gene, a Myc family gene and a Sox family gene. Also disclosed is a method for preparing the first recombinant vector, including inserting the at least two genes into a vector.

Abstract: A processor includes: an address generating unit that, when an instruction decoded by a decoding unit is an instruction to execute arithmetic processing on a plurality of operand sets each including a plurality of operands that are objects of the arithmetic processing, in parallel a plurality of times, generates an address set corresponding to each of the operand sets of the arithmetic processing for each time, based on a certain address displacement with respect to the plurality of operands included in each of the operand sets; a plurality of instruction queues that hold the generated address sets corresponding to the respective operand sets, in correspondence to respective processing units; and a plurality of processing units that perform the arithmetic processing in parallel on the operand sets obtained based on the respective address sets outputted by the plurality of instruction queues.

Abstract: A manufacturing device manufactures a bearing unit including an inner ring member outwardly fitted onto an end portion of a shaft main body of an inner shaft on one side in an axial direction and fixed by a swaged portion extending from the end portion. The manufacturing device includes: a rotating mechanism including a rotor which holds the other side of the inner shaft in the axial direction from below and rotates the inner shaft about a center axis of the inner shaft while the center axis is aligned with an up-down direction, the rotor being mounted below a processing area of the bearing unit; and a swaging mechanism mounted above the processing area and including a punch which is brought into contact with the swaged portion to plastically deform the swaged portion.

Abstract: A plurality of floating-point registers store data therein. A processing execution unit executes arithmetic processing by using data stored in the floating-point registers. A first switch and a second switch select a route connecting the processing execution unit and the floating-point registers. A switch control unit controls the first switch and the second switch so as to switch a route to be selected, based on a switching instruction from the processing execution unit.

Abstract: The present invention relates to a nuclear reprogramming factor having an action of reprogramming a differentiated somatic cell to derive an induced pluripotent stem (iPS) cell. The present invention also relates to the aforementioned iPS cells, methods of generating and maintaining iPS cells, and methods of using iPS cells, including screening and testing methods as well as methods of stem cell therapy. The present invention also relates to somatic cells derived by inducing differentiation of the aforementioned iPS cells.

Abstract: A plurality of floating-point registers store data therein. A processing execution unit executes arithmetic processing by using data stored in the floating-point registers. A first switch and a second switch select a route connecting the processing execution unit and the floating-point registers. A switch control unit controls the first switch and the second switch so as to switch a route to be selected, based on a switching instruction from the processing execution unit.

Abstract: A processor includes: an address generating unit that, when an instruction decoded by a decoding unit is an instruction to execute arithmetic processing on a plurality of operand sets each including a plurality of operands that are objects of the arithmetic processing, in parallel a plurality of times, generates an address set corresponding to each of the operand sets of the arithmetic processing for each time, based on a certain address displacement with respect to the plurality of operands included in each of the operand sets; a plurality of instruction queues that hold the generated address sets corresponding to the respective operand sets, in correspondence to respective processing units; and a plurality of processing units that perform the arithmetic processing in parallel on the operand sets obtained based on the respective address sets outputted by the plurality of instruction queues.

Abstract: A processor includes: a storage unit that stores instructions; a counting unit that specifies an instruction to be decoded by a count value; a decoding unit that decodes an instruction; and a control unit that, when the decoded instruction is a repeat instruction, updates the count value of the counting unit so as to cause repeat target instructions in number corresponding to a designated number of instructions, out of instructions succeeding the repeat instruction, to be repeatedly executed a designated number of repetition times, and generates updated operands being operation objects of the repeat target instructions that are to be executed for the second or later time, and when the repeat target instructions are to be executed for the second or later time, updates operands of the repeat target instructions for use in the second or later time execution, to the generated updated operands and outputs the updated operands.

Abstract: Provided are a modified laminin having a cell-growth regulatory molecule bound to at least one site selected from the ? chain N-terminus, the ? chain C-terminus, the ? chain N-terminus and the ? chain N-terminus of laminin or a heterotrimeric laminin fragment, a method for culturing cells in the presence of the modified laminin, a method for establishing iPS cells in the presence of the modified laminin, and a culture substrate coated with the modified laminin. Human stem cells cultured in a xeno-free environment with the use of the modified laminin of the present invention can be provided as highly safe human stem cells applicable to regenerative medicine.

Abstract: Provided is a method of producing an iPS cell, comprising bringing (a) Oct3/4 or a nucleic acid that encodes the same, (b) Klf4 or a nucleic acid that encodes the same, and (c) Sox2 or a nucleic acid that encodes the same, as well as (d1) L-Myc or a nucleic acid that encodes the same and/or (d2) a functional inhibitor of p53, into contact with a somatic cell. It is preferable that (a) a nucleic acid that encodes Oct3/4, (b) a nucleic acid that encodes Klf4, (c) a nucleic acid that encodes Sox2, (d1) a nucleic acid that encodes L-Myc and (e) a nucleic acid that encodes Lin28 or Lin28b be inserted into an episomal vector having loxP sequences placed in the same orientation on the 5? and 3? sides of a vector constituent essential for the replication of the vector, that (d2) a nucleic acid that encodes an shRNA against p53 be inserted into a vector ensuring transient expression (plasmid vector and the like), and that all these nucleic acids be transferred to a somatic cell.

Abstract: A method for sorting pluripotent cells using a compound which is eliminated from the pluripotent cells through the MDR1 transporter.