Patents by Inventor Masato TSURUDOME

Masato TSURUDOME has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN PARAINFLUENZA VIRUS TYPE 2 VECTOR AND VACCINE
    Publication number: 20180339038
    Abstract: The present invention relates to: a virus vector, which can effectively transfer a macromolecular antigenic peptide into target cells while maintaining a three-dimensional structure that is required for functioning as an antigen; and a vaccine utilizing the vector. Specifically, disclosed are: a virus vector, in which a nucleic acid encoding an antigenic polypeptide is integrated immediately 5? upstream of HN gene of an F gene-defective Paramyxoviridae virus gene, wherein the antigenic polypeptide is expressed as a fusion protein of 130 or more amino acid residues, fused with a TM sequence and/or a CT sequence derived from the virus.
    Type: Application
    Filed: June 13, 2016
    Publication date: November 29, 2018
    Applicants: Mie University, BioComo Inc.
    Inventors: Tetsuya Nosaka, Masato TSURUDOME, Masayuki FUKUMURA, Junpei OHTSUKA, Masao YUDA, Shiroh IWANAGA
  • Vaccine prepared utilizing human parainfluenza virus type 2 vector
    Patent number: 9695444
    Abstract: Disclosed are: a virus vector in which a gene encoding an antigenic polypeptide is integrated in human parainfluenza virus type 2 gene, wherein the antigenic polypeptide is expressed in the form of a fusion protein with a viral structural protein; and a method for producing the same. The virus vector of the present invention contains a quantitatively large amount of the antigenic peptide on the virus particle and can efficiently deliver the antigenic polypeptide to a target cell.
    Type: Grant
    Filed: December 25, 2013
    Date of Patent: July 4, 2017
    Assignees: BIOCOMO INC., MIE UNIVERSITY
    Inventors: Masayuki Fukumura, Junpei Ohtsuka, Tetsuya Nosaka, Masato Tsurudome, Mitsuo Kawano, Ken-ichiro Hara
  • VACCINE PREPARED UTILIZING HUMAN PARAINFLUENZA VIRUS TYPE 2 VECTOR
    Publication number: 20150329874
    Abstract: Disclosed are: a virus vector in which a gene encoding an antigenic polypeptide is integrated in human parainfluenza virus type 2 gene, wherein the antigenic polypeptide is expressed in the form of a fusion protein with a viral structural protein; and a method for producing the same. The virus vector of the present invention contains a quantitatively large amount of the antigenic peptide on the virus particle and can efficiently deliver the antigenic polypeptide to a target cell.
    Type: Application
    Filed: December 25, 2013
    Publication date: November 19, 2015
    Inventors: Masayuki FUKUMURA, Junpei OHTSUKA, Tetsuya NOSAKA, Masato TSURUDOME, Mitsuo KAWANO, Ken-ichiro HARA