Patents by Inventor Masatomo Rokushima

Masatomo Rokushima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TEST AGENT FOR VISCERAL OBESITY AND USE THEREOF
    Publication number: 20130317202
    Abstract: Disclosed are: a method for detecting (diagnosing) visceral obesity in a subject; a test agent useful for the method; a method for searching for a substance that can be used as an active ingredient for ameliorating visceral obesity; and an ameliorating agent for visceral obesity or a medicinal agent for preventing a metabolic disease developed as a result of the progression of visceral obesity. As the test agent, a polynucleotide which comprises at least 15 nucleotides and can hybridize with a nucleotide sequence for coiled-coil domain containing protein 3 (CCDC3) gene or a nucleotide sequence complementary to the nucleotide sequence under stringent conditions or an antibody capable of recognizing CCDC3 protein is used.
    Type: Application
    Filed: August 8, 2013
    Publication date: November 28, 2013
    Applicants: SHIONOGI & CO., LTD., RIKEN, SHIGA UNIVERSITY OF MEDICAL SCIENCE
    Inventors: Yoshihiro KAWAMURA, Masatomo ROKUSHIMA, Minoru SUZUKI, Tatsuya TAKAHASHI, Minoru IKEDA, Atsunori KASHIWAGI, Hiroshi MAEGAWA, Tohru TANI, Shiro MAEDA
  • Test agent for visceral obesity and use thereof
    Patent number: 8530392
    Abstract: Disclosed are: a method for detecting (diagnosing) visceral obesity in a subject; a test agent useful for the method; a method for searching for a substance that can be used as an active ingredient for ameliorating visceral obesity; and an ameliorating agent for visceral obesity or a medicinal agent for preventing a metabolic disease developed as a result of the progression of visceral obesity. As the test agent, a polynucleotide which comprises at least 15 nucleotides and can hybridize with a nucleotide sequence for coiled-coil domain containing protein 3 (CCDC3) gene or a nucleotide sequence complementary to the nucleotide sequence under stringent conditions or an antibody capable of recognizing CCDC3 protein is used.
    Type: Grant
    Filed: May 13, 2010
    Date of Patent: September 10, 2013
    Assignees: Shionogi & Co., Ltd., Shiga University of Medical Science, Riken
    Inventors: Yoshihiro Kawamura, Masatomo Rokushima, Minoru Suzuki, Tatsuya Takahashi, Minoru Ikeda, Atsunori Kashiwagi, Hiroshi Maegawa, Tohru Tani, Shiro Maeda
  • TEST AGENT FOR VISCERAL OBESITY AND USE THEREOF
    Publication number: 20120066777
    Abstract: Disclosed are: a method for detecting (diagnosing) visceral obesity in a subject; a test agent useful for the method; a method for searching for a substance that can be used as an active ingredient for ameliorating visceral obesity; and an ameliorating agent for visceral obesity or a medicinal agent for preventing a metabolic disease developed as a result of the progression of visceral obesity. As the test agent, a polynucleotide which comprises at least 15 nucleotides and can hybridize with a nucleotide sequence for coiled-coil domain containing protein 3 (CCDC3) gene or a nucleotide sequence complementary to the nucleotide sequence under stringent conditions or an antibody capable of recognizing CCDC3 protein is used.
    Type: Application
    Filed: May 13, 2010
    Publication date: March 15, 2012
    Applicants: SHIONOGI & CO., LTD., RIKEN, SHIGA UNIVERSITY OF MEDICAL SCIENCE
    Inventors: Yoshihiro Kawamura, Masatomo Rokushima, Minoru Suzuki, Tatsuya Takahashi, Minoru Ikeda, Atsunori Kashiwagi, Hiroshi Maegawa, Tohru Tani, Shiro Maeda
  • Support for ligand immobilization
    Publication number: 20050239066
    Abstract: A support for ligand immobilization coated with a polyanion which has been activated beforehand.
    Type: Application
    Filed: September 20, 2002
    Publication date: October 27, 2005
    Inventors: Kiyozo Asada, Nobuyuki Imose, Osamu Takeda, Masatomo Rokushima, Ikunoshin Kato
  • Amplified nucleic acids and immobilized products thereof
    Publication number: 20050118578
    Abstract: A nucleic acid, which is provided in a large amount through a nucleic acid amplification reaction with the use of chimeric oligonucleotide primers, is constructed in a state of containing a modified deoxyribonucleotide for immobilizing the nucleic acid to a solid phase and then immobilized to a solid phase at a high efficiency, thereby giving an immobilized nucleic acid product with excellent qualities.
    Type: Application
    Filed: February 6, 2002
    Publication date: June 2, 2005
    Applicant: TAKARA BIO INC.
    Inventors: Junichi Mineno, Osamu Takeda, Masatomo Rokushima, Takashi Uemori, Shigekazu Hokazono, Hiroyuki Mukai, Shusaku Yamashita, Hiroaki Sagawa, Kiyozo Asada, Ikunoshin Kato
  • Method of screening physiologically active substance
    Publication number: 20040081618
    Abstract: The present invention provides a method of screening a biologically active substance or a candidate substance for a biologically active substance, possessing an activity for controlling gene expression to the same extent to that of DGE; a gene controlling agent which is effective for maintaining homeostasis in a living body, for instance, purposed for mitigation or prevention of stress; and a method of controlling a gene.
    Type: Application
    Filed: April 3, 2003
    Publication date: April 29, 2004
    Inventors: Tatsuji Enoki, Shusaku Yamashita, Masatomo Rokushima, Junichi Mineno, Hiroaki Sagawa, Ikunoshin Kato