Patents by Inventor Masatoshi Kuroda

Masatoshi Kuroda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11398032
    Abstract: [Problem] To evaluate objective cell groups by estimating a mixing ratio of objective cell group without affecting treatment itself and its production process when the objective cell groups include plural kinds of cell groups having different attributes, and to provide an image analysis system and a culture management system capable of accurately perform a quality control and a production control with low cost. [Solution] The cell quality evaluation system 1 detects a feature amount in each cell easily analyzable from images, and estimates a mixing ratio of each of plural kinds of cell groups included in the objective cell groups based on a distribution of the detected feature amount and pre-recorded information of the feature amount. As the feature amount, the embodiment uses a migration speed of each cell, easily distinguishable by analyzing tracking of each cell from plural images in time series.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: July 26, 2022
    Assignees: DAI NIPPON PRINTING CO., LTD., TERUMO KABUSHIKI KAISHA
    Inventors: Ryoma Bise, Yoshitaka Maeda, Masatoshi Kuroda, Kazumasa Yamaki, Ryohei Takeuchi, Fumiya Ohashi, Kouichirou Yori
  • Publication number: 20190236784
    Abstract: [Problem] To evaluate objective cell groups by estimating a mixing ratio of objective cell group without affecting treatment itself and its production process when the objective cell groups include plural kinds of cell groups having different attributes, and to provide an image analysis system and a culture management system capable of accurately perform a quality control and a production control with low cost. [Solution] The cell quality evaluation system 1 detects a feature amount in each cell easily analyzable from images, and estimates a mixing ratio of each of plural kinds of cell groups included in the objective cell groups based on a distribution of the detected feature amount and pre-recorded information of the feature amount. As the feature amount, the embodiment uses a migration speed of each cell, easily distinguishable by analyzing tracking of each cell from plural images in time series.
    Type: Application
    Filed: July 13, 2017
    Publication date: August 1, 2019
    Inventors: Ryoma BISE, Yoshitaka MAEDA, Masatoshi KURODA, Kazumasa YAMAKI, Ryohei TAKEUCHI, Fumiya OHASHI, Kouichirou YORI
  • Publication number: 20190192271
    Abstract: In accordance with the present invention, an implant in which cells are arranged in a fine pattern that is available for immediate implantation and that does not need to be removed after implantation is provided. The present invention relates to a cell-containing sheet, which comprises cells and a support comprising a bioabsorbable material, in which the support has a cell adhesion protein-containing layer on the surface thereof and the cells form a pattern on the support.
    Type: Application
    Filed: February 28, 2019
    Publication date: June 27, 2019
    Applicants: National University Corporation Tokyo Medical and Dental University, DAI NIPPON PRINTING CO., LTD.
    Inventors: Ikuo MORITA, Akiko KOBAYASHI, Hideshi HATTORI, Masatoshi KURODA
  • Patent number: 10258456
    Abstract: In accordance with the present invention, an implant in which cells are arranged in a fine pattern that is available for immediate implantation and that does not need to be removed after implantation is provided. The present invention relates to a cell-containing sheet, which comprises cells and a support comprising a bioabsorbable material, in which the support has a cell adhesion protein-containing layer on the surface thereof and the cells form a pattern on the support.
    Type: Grant
    Filed: July 20, 2016
    Date of Patent: April 16, 2019
    Assignees: National University Corporation Tokyo Medical and Dental University, DAI NIPPON PRINTING CO., LTD.
    Inventors: Ikuo Morita, Akiko Kobayashi, Hideshi Hattori, Masatoshi Kuroda
  • Patent number: 10219888
    Abstract: In accordance with the present invention, an implant in which cells are arranged in a fine pattern that is available for immediate implantation and that does not need to be removed after implantation is provided. The present invention relates to a cell-containing sheet, which comprises cells and a support comprising a bioabsorbable material, in which the support has a cell adhesion protein-containing layer on the surface thereof and the cells form a pattern on the support.
    Type: Grant
    Filed: June 19, 2006
    Date of Patent: March 5, 2019
    Assignees: National University Corporation Tokyo Medical and Dental University, DAI NIPPON PRINTING CO., LTD.
    Inventors: Ikuo Morita, Akiko Kobayashi, Hideshi Hattori, Masatoshi Kuroda
  • Publication number: 20170226456
    Abstract: This invention provides a cost-effective technique for mass-production of a cell culture vessel that allows mass cell culture to be performed in a manner that allows cells to be stably detached from the culture vessel. Specifically, the invention provides a method for producing a cell culture vessel suitable for large-capacity culture comprising cutting a long-sized cell support film to obtain a sheet-like cell support film, fixing the film to a first member, which is not closed, and bonding other members thereto. Thus, a cell culture vessel comprising a container section in which a cell support film is fixed to an inner wall surface can be produced.
    Type: Application
    Filed: January 23, 2017
    Publication date: August 10, 2017
    Applicant: Dai Nippon Printing Co., Ltd.
    Inventors: Masatoshi Kuroda, Katsunori Tsuchiya, Masahiko Hase, Taro Nagai, Yumiko Narita, Kazumasa Yamaki
  • Patent number: 9587219
    Abstract: This invention provides a cost-effective technique for mass-production of a cell culture vessel that allows mass cell culture to be performed in a manner that allows cells to be stably detached from the culture vessel. Specifically, the invention provides a method for producing a cell culture vessel suitable for large-capacity culture comprising cutting a long-sized cell support film to obtain a sheet-like cell support film, fixing the film to a first member, which is not closed, and bonding other members thereto. Thus, a cell culture vessel comprising a container section in which a cell support film is fixed to an inner wall surface can be produced.
    Type: Grant
    Filed: October 29, 2012
    Date of Patent: March 7, 2017
    Assignee: Dai Nippon Printing Co., Ltd.
    Inventors: Masatoshi Kuroda, Katsunori Tsuchiya, Masahiko Hase, Taro Nagai, Yumiko Narita, Kazumasa Yamaki
  • Publication number: 20160324623
    Abstract: In accordance with the present invention, an implant in which cells are arranged in a fine pattern that is available for immediate implantation and that does not need to be removed after implantation is provided. The present invention relates to a cell-containing sheet, which comprises cells and a support comprising a bioabsorbable material, in which the support has a cell adhesion protein-containing layer on the surface thereof and the cells form a pattern on the support.
    Type: Application
    Filed: July 20, 2016
    Publication date: November 10, 2016
    Applicants: Tokyo Medical and Dental University, DAI NIPPON PRINTING CO., LTD.
    Inventors: Ikuo MORITA, Akiko KOBAYASHI, Hideshi HATTORI, Masatoshi KURODA
  • Patent number: 9249386
    Abstract: A main object of the present invention is to provide a cell transfer substrate capable of transplanting cells, maintaining a pattern as it is, on a living body tissue or the like, even when: the size of the cell sheet is extremely small; the cells are cultured sparsely; the cells are in a form of a small colony; or the cells are cultured in a pattern, for example, as a blood vessel, a vessel network such as a lymphatic vessel, or a nerve network, and to provide a substrate for cell transfer to be used for the cell transfer substrate. In order to achieve the above-mentioned object, the present invention provides a substrate for cell transfer comprising: a polymer base material; an intermediate layer formed on the polymer base material; and a cell transfer layer formed on the intermediate layer.
    Type: Grant
    Filed: June 5, 2006
    Date of Patent: February 2, 2016
    Assignee: DAI NIPPON PRINTING CO., LTD.
    Inventors: Hideshi Hattori, Masatoshi Kuroda
  • Patent number: 9127270
    Abstract: This invention provides a cell pattern recovery tool comprising a base material layer having a surface subjected to easy adhesion treatment, a temperature responsive polymer layer that is provided on the base material layer and has a surface subjected to silane treatment, and a cell adhesion inhibiting material layer provided on the temperature responsive polymer layer. According to the present invention, a cell pattern can be rapidly recovered while maintaining the cell pattern stably and reliably under minimally invasive conditions for the cells.
    Type: Grant
    Filed: August 11, 2009
    Date of Patent: September 8, 2015
    Assignees: TOKYO WOMEN'S MEDICAL UNIVERSITY, DAI NIPPON PRINTING CO., LTD.
    Inventors: Teruo Okano, Masayuki Yamato, Tatsuya Shimizu, Masatoshi Kuroda
  • Patent number: 9090479
    Abstract: Ceramic powder having a BET specific surface area within a range of from 0.1 to 2.0 m2/g as measured according to the N2 absorption method and an average particle diameter within a range of from 0.8 to 100 ?m and composed of titanium oxide or a titanate; a dielectric composite material containing a synthetic resin and the ceramic powder; and a dielectric antenna with an antenna part formed of a conductor circuit provided on a dielectric substrate formed from the dielectric composite material.
    Type: Grant
    Filed: September 7, 2009
    Date of Patent: July 28, 2015
    Assignees: SUMITOMO ELECTRIC INDUSTRIES, LTD., TODA KOGYO CORP.
    Inventors: Masatoshi Kuroda, Takahisa Yamashita, Kazutoshi Sanada, Shinsuke Maruyama
  • Publication number: 20140326391
    Abstract: This invention provides a cost-effective technique for mass-production of a cell culture vessel that allows mass cell culture to be performed in a manner that allows cells to be stably detached from the culture vessel. Specifically, the invention provides a method for producing a cell culture vessel suitable for large-capacity culture comprising cutting a long-sized cell support film to obtain a sheet-like cell support film, fixing the film to a first member, which is not closed, and bonding other members thereto. Thus, a cell culture vessel comprising a container section in which a cell support film is fixed to an inner wall surface can be produced.
    Type: Application
    Filed: October 29, 2012
    Publication date: November 6, 2014
    Applicant: Dai Nippon Printing Co., Ltd.
    Inventors: Masatoshi Kuroda, Katsunori Tsuchiya, Masahiko Hase, Taro Nagai, Yumiko Narita, Kazumasa Yamaki
  • Patent number: 8835173
    Abstract: An object of the present invention is to provide a means capable of transferring a cell sheet, a cell pattern or the like to a desired material at a high speed. The present invention provides a substrate for cell culture comprising a base and a cell adhesive region formed on a surface of the base, wherein the cell adhesive region is formed of a film that is rendered cell adhesive by applying an oxidation treatment and/or a decomposition treatment to a cell-adhesion inhibitory hydrophilic film containing an organic compound having a carbon-oxygen bond.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: September 16, 2014
    Assignee: Dai Nippon Printing Co., Ltd.
    Inventors: Hideshi Hattori, Norihiko Okochi, Masatoshi Kuroda, Kazunari Ikeda
  • Patent number: 8741645
    Abstract: The present invention provides a method for performing a biological test under conditions in which an artificially prepared cell pattern with initial position coordinates that can be determined is three-dimensionally cultured within a gelled matrix. The present invention relates to a biological test method that comprises testing a biological indicator with reference to at least one selected from the group consisting of cell proliferation, cell movement, and cell differentiation in a cell pattern substantially embedded in gel. The present invention also relates to a kit for the biological test method.
    Type: Grant
    Filed: April 22, 2011
    Date of Patent: June 3, 2014
    Assignee: Dai Nippon Printing Co., Ltd.
    Inventors: Hideshi Hattori, Norihiko Okochi, Masatoshi Kuroda, Masahiko Hase
  • Patent number: 8592139
    Abstract: The present invention provides a method for performing a biological test under conditions in which an artificially prepared cell pattern with initial position coordinates that can be determined is three-dimensionally cultured within a gelled matrix. The present invention relates to a biological test method that comprises testing a biological indicator with reference to at least one selected from the group consisting of cell proliferation, cell movement, and cell differentiation in a cell pattern substantially embedded in gel. The present invention also relates to a kit for the biological test method.
    Type: Grant
    Filed: November 8, 2007
    Date of Patent: November 26, 2013
    Assignee: Dai Nippon Printing Co., Ltd.
    Inventors: Hideshi Hattori, Norihiko Okochi, Masatoshi Kuroda, Masahiko Hase
  • Publication number: 20130234912
    Abstract: An antenna apparatus capable of improving antenna characteristics as well as miniaturizing a size is provided. An antenna apparatus includes a base, an antenna conductor, and a terminal as an external connection terminal. The base is made of a dielectric composite material containing resin and ceramic powder. The antenna conductor is arranged on a surface of the base. The terminal is electrically connected to the antenna conductor. A relative permittivity (?r) and a dielectric tangent (tan ?) of the dielectric composite material satisfy a relation of: tan ??0.0024×e(0.0341×?r).
    Type: Application
    Filed: March 5, 2013
    Publication date: September 12, 2013
    Applicants: SUMITOMO ELECTRIC INDUSTRIES, LTD., SUMITOMO ELECTRIC PRINTED CIRCUITS, INC.
    Inventors: Masahiko KOUCHI, Katsuyuki IMAI, Masatoshi KURODA, Rikio TANAKA
  • Patent number: 8391019
    Abstract: A connection terminal includes a frame body including first and second support parts positioned to face each other; and a third support part having first and second ends connected to an end of the first support part and an end of the second support part, respectively; first elastic contact pieces provided on the first support part on a first side from which a terminal is to be inserted and having respective first contact parts configured to contact a peripheral surface of the terminal; second elastic contact pieces provided on the second support part on the first side and having respective second contact parts configured to contact the peripheral surface of the terminal and positioned to face the first contact parts; and a third elastic contact piece provided on the frame body on a second side opposite to the first side and configured to contact an end portion of the terminal.
    Type: Grant
    Filed: September 3, 2010
    Date of Patent: March 5, 2013
    Assignee: Mitsumi Electric Co., Ltd.
    Inventors: Masatoshi Kuroda, Toru Yoshino, Eiji Yoshida, Hirotaka Yamamoto
  • Publication number: 20110227796
    Abstract: Ceramic powder having a BET specific surface area within a range of from 0.1 to 2.0 m2/g as measured according to the N2 absorption method and an average particle diameter within a range of from 0.8 to 100 ?m and composed of titanium oxide or a titanate; a dielectric composite material containing a synthetic resin and the ceramic powder; and a dielectric antenna with an antenna part formed of a conductor circuit provided on a dielectric substrate formed from the dielectric composite material.
    Type: Application
    Filed: September 7, 2009
    Publication date: September 22, 2011
    Applicants: SUMITOMO ELECTRIC INDUSTRIES, LTD, TODA KOGYO CORP.
    Inventors: Masatoshi Kuroda, Takahisa Yamashita, Kazutoshi Sanada, Shinsuke Maruyama
  • Publication number: 20110207220
    Abstract: This invention provides a cell pattern recovery tool comprising a base material layer having a surface subjected to easy adhesion treatment, a temperature responsive polymer layer that is provided on the base material layer and has a surface subjected to silane treatment, and a cell adhesion inhibiting material layer provided on the temperature responsive polymer layer. According to the present invention, a cell pattern can be rapidly recovered while maintaining the cell pattern stably and reliably under minimally invasive conditions for the cells.
    Type: Application
    Filed: August 11, 2009
    Publication date: August 25, 2011
    Applicants: TOKYO WOMEN'S MEDICAL UNIVERSITY, DAI NIPPON PRINTING CO., LTD.
    Inventors: Teruo Okano, Masayuki Yamato, Tatsuya Shimizu, Masatoshi Kuroda
  • Publication number: 20110201116
    Abstract: The present invention provides a method for performing a biological test under conditions in which an artificially prepared cell pattern with initial position coordinates that can be determined is three-dimensionally cultured within a gelled matrix. The present invention relates to a biological test method that comprises testing a biological indicator with reference to at least one selected from the group consisting of cell proliferation, cell movement, and cell differentiation in a cell pattern substantially embedded in gel. The present invention also relates to a kit for the biological test method.
    Type: Application
    Filed: April 22, 2011
    Publication date: August 18, 2011
    Applicant: Dai Nippon Printing Co., Ltd.
    Inventors: Hideshi HATTORI, Norihiko OKOCHI, Masatoshi KURODA, Masahiko HASE