Abstract: The present invention aims to provide a novel drug delivery system (DDS) technique capable of selectively delivering a drug (compound containing oligonucleotides for producing at least partially functional dystrophin protein) to muscle tissues such as cardiac muscle, skeletal muscle and the like and efficiently introducing the drug into the muscle cells. The present invention relates to a conjugate or a salt thereof including the following: (1) a peptide that binds to a transferrin receptor, and contains the amino acid sequence shown in SEQ ID NO: 1 (Ala-Val-Phe-Val-Trp-Asn-Tyr-Tyr-Ile-Ile-Ser-Cys); or an amino acid sequence resulting from substitution, deletion, addition, and/or insertion of not less than one and not more than 10 amino acid residues in the amino acid sequence shown in SEQ ID NO: 1, and (2) a compound comprising an oligonucleotide for producing an at least partially functional dystrophin protein.

Abstract: The present invention addresses the problem of providing an atomizer that is particularly suitable for atomizing a cosmetic. An atomizer (1) for atomizing a coating composition such as a cosmetic using a compressed gas. The atomizer (1) comprises: an atomizer main body (3) provided with a nozzle (8) that is a port for jetting the coating composition; and a gas supply means (30) for supplying the compressed gas to the atomizer main body (3). In the atomizer main body (3), a composition supply tank (2) for supplying the coating composition, an operation part (6) for jetting the coating composition from the nozzle (8) and an insertion part (7), into which a user's fingertip is to be inserted, are formed.

Abstract: The present invention addresses the problem of providing an atomizer that is particularly suitable for atomizing a cosmetic. An atomizer (1) for atomizing a coating composition such as a cosmetic using a compressed gas. The atomizer (1) comprises: an atomizer main body (3) provided with a nozzle (8) that is a port for jetting the coating composition; and a gas supply means (30) for supplying the compressed gas to the atomizer main body (3). In the atomizer main body (3), a composition supply tank (2) for supplying the coating composition, an operation part (6) for jetting the coating composition from the nozzle (8) and an insertion part (7), into which a user's fingertip is to be inserted, are formed.

Abstract: There is disclosed a molding apparatus which includes an ejector pin (16) having, at its forward end, an ejecting portion (33) permitted to abut against an end surface of a tubular elastic resin product (28) and gradually flaring out toward a forward end thereof, and an annular recess (9) for receiving an annular edge portion (26), whereby the tubular elastic resin product (28) is released from a cavity (22) without damages to a base portion of the annular edge portion (26).

Abstract: A flush mounting molding of the present invention has a strip-shaped head covering a channel formed between a window frame and a windshield glass of an automobile, and a leg, to be inserted and installed into the channel, having a window frame contacting lip and a windshield glass receiving lip and formed integrally and vertically on the bottom surface of the strip-shaped head. The window frame contacting lip is divided into a plurality of window frame contacting lip members by slits in the longitudinal direction thereof, and the length of the window frame contacting lip members is varied in the direction toward the window frame. Thus, some of the window frame contacting lip members contact with the window frame in approximately perpendicular manner. Accordingly, the flush mounting molding does not come out of the channel. Thus, no defective automobile assembly due to the come-out occurs, and the productivity of the automobile assembly is improved.