Patents by Inventor Masatoshi Nishizawa
Masatoshi Nishizawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230250415Abstract: The present disclosure provides a technique for introducing an antigen receptor-encoding nucleic acid into a definite site in a nucleic acid that is contained in an immune cell of a target organism. In the technique according to the present disclosure, a vector, which contains an antigen receptor-encoding nucleic acid, and a nuclease are introduced into an immune cell. The nuclease cleaves the vector and the genome sequence of the immune cell. The vector can be configured so that, when cleaved with the nuclease, a sequence, which is an antigen receptor-encoding sequence and which is introduced by microhomology-mediated end-joining (MMEJ) at the nuclease cleavage site of the genome sequence of the immune cell, is formed.Type: ApplicationFiled: November 13, 2020Publication date: August 10, 2023Inventors: Tatsuo Ichinohe, Takashi Yamamoto, Tetsushi Sakuma, Yasuko Honjo, Takakazu Kawase, Masatoshi Nishizawa, Ryuji Suzuki, Kenta Magoori, Hiroyuki Sato
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Patent number: 10240126Abstract: A method for producing hematopoietic stem cells and/or hematopoietic progenitor cells from pluripotent stem cells is described. The method includes a step of culturing pluripotent stem cells in the presence of IGF2. A method is described for selecting an induced pluripotent stem cell(s) having high capacity to differentiate into hematopoietic stem cells and/or hematopoietic progenitor cells, or into blood cells, based on the expression level(s) of one or more genes such as TRIM58, CTSF, FAM19A5, and TCERG1L genes, or on the DNA methylation state(s) of the TRIM58, CSMD1, and/or FAM19A5 gene(s).Type: GrantFiled: June 11, 2014Date of Patent: March 26, 2019Assignee: KYOTO UNIVERSITYInventors: Shinya Yamanaka, Yoshinori Yoshida, Masatoshi Nishizawa
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Publication number: 20160137981Abstract: A method for producing hematopoietic stem cells and/or hematopoietic progenitor cells from pluripotent stem cells is described. The method includes a step of culturing pluripotent stem cells in the presence of IGF2. A method is described for selecting an induced pluripotent stem cell(s) having high capacity to differentiate into hematopoietic stem cells and/or hematopoietic progenitor cells, or into blood cells, based on the expression level(s) of one or more genes such as TRIM58, CTSF, FAM19A5, and TCERG1L genes, or on the DNA methylation state(s) of the TRIM58, CSMD1, and/or FAM19A5 gene(s).Type: ApplicationFiled: June 11, 2014Publication date: May 19, 2016Inventors: Shinya Yamanaka, Yoshinori Yoshida, Masatoshi Nishizawa
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Patent number: 8256495Abstract: A fan is enclosed in the enclosure of an electronic apparatus. The fan discharges air out of a ventilation opening of the fan. Heat radiating fins are located in an air passage extending from the ventilation opening. A dust catcher is removably mounted on an outside surface of the enclosure into an opening of the enclosure. The dust catcher is located in the air passage between the heat radiating fins and the ventilation opening. The dust catcher serves to catch the dust in the air passage. The dust catcher is removed from the enclosure along with the dust.Type: GrantFiled: June 2, 2006Date of Patent: September 4, 2012Assignee: Fujitsu LimitedInventors: Masahiko Hattori, Masuo Ohnishi, Tadanori Tachikawa, Masatoshi Nishizawa, Tomoki Harada, Goro Nakagai, Toyohiro Kato
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Patent number: 7930071Abstract: The inventors have revealed that the actual rotation speed of the rotor in a fan structured as a centrifugal fan exceeds the designated rotation speed if the ventilation opening of the centrifugal fan is occluded. If a larger amount of dust accumulates at the ventilation opening of the centrifugal fan, for example, the actual rotation speed of the rotor in the centrifugal fan exceeds the designated rotation speed by a predetermined deviation. The accumulation of dust at the ventilation opening can in this manner be observed in a facilitated manner. The occlusion of the ventilation opening can thus be detected.Type: GrantFiled: September 9, 2008Date of Patent: April 19, 2011Assignee: Fujitsu LimitedInventors: Masatoshi Nishizawa, Tomoki Harada, Goro Nakagai, Toyohiro Kato
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Patent number: 7652877Abstract: An electronic apparatus includes a first part, a second part, and a rotating holding part configured to rotatably hold the second part to the first part, wherein, in addition to a closed state in which the first part and the second part are placed upon one another and an opened state in which the second part is apart from the first part so that both first and second parts are opened, an intermediate state is provided in which respective opposite faces of the first and second parts are apart by a predetermined space and thereby radiation is available, and a lifting mechanism is provided to cause an end of the second part to be apart from a corresponding end of the first part in the rotating holding part so that the opposite faces of both parts are apart by the predetermined space and thus the intermediate state is created.Type: GrantFiled: March 5, 2008Date of Patent: January 26, 2010Assignee: Fujitsu LimitedInventor: Masatoshi Nishizawa
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Publication number: 20090009967Abstract: The inventors have revealed that the actual rotation speed of the rotor in a fan structured as a centrifugal fan exceeds the designated rotation speed if the ventilation opening of the centrifugal fan is occluded. If a larger amount of dust accumulates at the ventilation opening of the centrifugal fan, for example, the actual rotation speed of the rotor in the centrifugal fan exceeds the designated rotation speed by a predetermined deviation. The accumulation of dust at the ventilation opening can in this manner be observed in a facilitated manner. The occlusion of the ventilation opening can thus be detected.Type: ApplicationFiled: September 9, 2008Publication date: January 8, 2009Applicant: FUJITSU LIMITEDInventors: Masatoshi Nishizawa, Tomoki Harada, Goro Nakagai, Toyohiro Kato
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Publication number: 20080218955Abstract: An electronic apparatus includes a first part, a second part, and a rotating holding part configured to rotatably hold the second part to the first part, wherein, in addition to a closed state in which the first part and the second part are placed upon one another and an opened state in which the second part is apart from the first part so that both first and second parts are opened, an intermediate state is provided in which respective opposite faces of the first and second parts are apart by a predetermined space and thereby radiation is available, and a lifting mechanism is provided to cause an end of the second part to be apart from a corresponding end of the first part in the rotating holding part so that the opposite faces of both parts are apart by the predetermined space and thus the intermediate state is created.Type: ApplicationFiled: March 5, 2008Publication date: September 11, 2008Applicant: FUJITSU LIMITEDInventor: Masatoshi Nishizawa
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Publication number: 20070131383Abstract: A fan is enclosed in the enclosure of an electronic apparatus. The fan discharges air out of a ventilation opening of the fan itself. Heat radiating fins are located in an air passage extending from the ventilation opening. A dust catcher is removably mounted in an opening of the enclosure from the outside of the enclosure. The dust catcher is located in the air passage between the heat radiating fins and the ventilation opening. The dust catcher serves to catch the dust in the air passage. The dust catcher is removed from the enclosure along with the dust. The dust is thus reliably cleared from the air passage. The dust catcher can then be cleaned. The cleaned dust catcher can again be set in the opening of the enclosure. Airflow of a sufficient amount is in this manner always kept in the air passage.Type: ApplicationFiled: June 2, 2006Publication date: June 14, 2007Applicant: FUJITSU LIMITEDInventors: Masahiko Hattori, Masuo Ohnishi, Tadanori Tachikawa, Masatoshi Nishizawa, Tomoki Harada, Goro Nakagai, Toyohiro Kato
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Patent number: 6856061Abstract: A synchronous resolver has: a stator including a plurality of stator poles disposed at regular intervals along the circumferential direction of a ring-shaped stator base portion, the stator poles comprise a plurality of phases; coil bobbins former-wounded stator coils therearound are respectively fitted with and mounted on their associated ones of the stator poles; and, a rotor shiftable in angle with respect to the stator to thereby vary a reluctance component in a gap existing between the stator and the rotor, wherein the coil bobbins are set the positions of the stator coils freely in such a manner that the resolver signals of the respective phases balance well.Type: GrantFiled: November 12, 2002Date of Patent: February 15, 2005Assignee: NSK Ltd.Inventors: Masatoshi Nishizawa, Masaki Kuwahara, Masamitsu Kamimura
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Publication number: 20030090223Abstract: A synchronous resolver has: a stator including a plurality of stator poles disposed at regular intervals along the circumferential direction of a ring-shaped stator base portion, the stator poles comprise a plurality of phases; coil bobbins former-wounded stator coils therearound are respectively fitted with and mounted on their associated ones of the stator poles; and, a rotor shiftable in angle with respect to the stator to thereby vary a reluctance component in a gap existing between the stator and the rotor, wherein the coil bobbins are set the positions of the stator coils freely in such a manner that the resolver signals of the respective phases balance well.Type: ApplicationFiled: November 12, 2002Publication date: May 15, 2003Applicant: NSK LTD.Inventors: Masatoshi Nishizawa, Masaki Kuwahara, Masamitsu Kamimura
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Patent number: 4729742Abstract: An improved electric power distribution track comprises a metal-reinforced duct and at least three conductors extending along the length thereof. The duct is shaped to have a top wall, a pair of lateral sidewalls and a lengthwise bottom opening, and is composed of a correspondingly shaped metal-made core channel member covered by an insulation sheath of a plastic material. Three conductors are disposed on the inner sheath in a trigonous arrangement with one of the conductors on the top wall and the two others on the opposite sidewalls. Integrally projecting from the corresponding portions of the inner sheath are support members for holding the respective conductors at positions spaced inwardly from the inner periphery of the sheath. The support member on the top wall is connected to those on each of the sidewalls by a connection rib integrally extending therebetween for reinforcing the support members by one another to thereby retain the conductors held thereby in positions.Type: GrantFiled: August 22, 1986Date of Patent: March 8, 1988Assignee: Matsushita Electric Works, Ltd.Inventors: Isao Onishi, Hiromi Kinoshita, Masatoshi Nishizawa
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Patent number: 4312210Abstract: A method for warm forging a cup-shaped piece is disclosed. In warm forging a blank is heated between 400.degree. and 800.degree. C. and is inserted within a die having a cross sectional area substantially larger than that of the blank. The ends of the blank are clamped between a recess in the die and a recess in an upsetting punch and the upsetting punch compresses the blank until its sides become sufficiently bulged to almost touch, or touch, the sides of the die. The upsetting punch is then removed and a backward extruding punch is press fitted into the bulged blank and the blank is extruded to form a cup. The extrusion punch is lubricated and cooled by lubricant and coolant applicators at a position remote from the die so that the blank is not prematurely cooled by the coolant.Type: GrantFiled: March 14, 1980Date of Patent: January 26, 1982Assignees: Kobe Steel Limited, Nippon Koshuha Steel Co. Ltd.Inventors: Masatoshi Nishizawa, Toshihiro Minami, Takeshi Nakahara, Toyofumi Hasegawa