Patents by Inventor Masatsugu Ozasa
Masatsugu Ozasa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220170841Abstract: A detection method according to one or more embodiments may include transporting a rack holding a reaction vessel along a first axis toward a sample dispensing position, linearly moving the sample dispensing pipette above the rack along a second axis intersecting the first axis and dispensing a sample into the reaction vessel located at the sample dispensing position, transporting the rack along the first axis toward a reagent dispensing position; linearly moving a reagent dispensing pipette above the rack along a third axis intersecting the first axis, and dispensing a reagent into the reaction vessel located at the reagent dispensing position, and detecting a detection target in a measurement specimen prepared from the sample and the reagent.Type: ApplicationFiled: November 29, 2021Publication date: June 2, 2022Applicant: SYSMEX CORPORATIONInventors: Masatsugu OZASA, Daiki FUJIWARA, Daiki MITA, Takaaki OKAJIMA, Hideki HIRAYAMA
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Patent number: 10309877Abstract: Disclosed is a method for analyzing atypical cells in urine including: mixing urine, a diluent containing a surfactant, and a nucleic acid staining reagent to prepare a measurement specimen; irradiating the measurement specimen with light to detect scattered light and fluorescence light emitted from cells whose nucleic acids are stained; and detecting atypical cells contained in the measurement specimen distinguishably from white blood cells depending on a first characteristic parameter based on the scattered light and a second characteristic parameter based on the fluorescence light.Type: GrantFiled: August 20, 2015Date of Patent: June 4, 2019Assignee: Sysmex CorporationInventors: Shota Tateyama, Masanori Kawano, Masatsugu Ozasa
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Patent number: 9835559Abstract: A urine specimen analysis device includes a specimen drawing portion, a sample preparing portion, a measurement portion, and an information processing portion. The specimen drawing portion draws a first aliquot and a second aliquot from a urine specimen. The sample preparing portion prepares a first measurement sample by mixing the first aliquot and a first staining dye that stains red blood cells, and a second measurement sample by mixing the second aliquot and a second staining dye that stains nucleic acids. The measurement portion measures fluorescence emitted from the first measurement sample prepared by the sample preparing portion, and fluorescence emitted from the second measurement sample prepared by the sample preparing portion.Type: GrantFiled: August 27, 2015Date of Patent: December 5, 2017Assignee: Sysmex CorporationInventors: Masatsugu Ozasa, Kanako Nagaoka, Akinori Kawai, Masanori Kawano
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Patent number: 9719123Abstract: Disclosed is a urine sample analyzer for analyzing particles contained in a urine sample and outputting analytical results. The analyzer includes a flow cell that accepts a measurement specimen, the measurement specimen comprising a urine sample mixed with a reagent, a light irradiation unit positioned to irradiate the flowing measurement specimen with light, a light detector that detects light from individual particles in the flowing measurement specimen, and a data processor that receives signal from the light detector, processes the signal to obtain parameter information corresponding to a length of a cell cluster, and classifies fungi in the measurement specimen into groups by using the parameter information.Type: GrantFiled: October 27, 2014Date of Patent: August 1, 2017Assignee: SYSMEX CORPORATIONInventors: Shota Tateyama, Masanori Kawano, Masatsugu Ozasa
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Patent number: 9664669Abstract: Disclosed is a urine specimen analyzing method which improves the detection of casts in a urine specimen by flowing a measurement sample containing a urine specimen through a flow cell, irradiating light on the measurement sample flowing through the flow cell, generating a signal waveform indicating a temporal change of intensity of light given off by the measurement sample, and detecting casts distinguishably from mucus threads contained in the urine specimen, based on information related to respective slope at both end sides of the signal waveform corresponding to each formed element contained in the urine specimen.Type: GrantFiled: March 30, 2015Date of Patent: May 30, 2017Assignee: Sysmex CorporationInventors: Masatsugu Ozasa, Keisuke Tsutsumida, Kenji Hanamura, Kunio Ueno
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Patent number: 9551657Abstract: Disclosed is a sample analyzer which comprises: a sample preparing section configured to prepare a measurement sample by mixing a sample and a nucleic acid staining reagent; an optical detector configured to irradiate light on cells contained in the measurement sample, receive fluorescent light given off by the irradiated cells, and output fluorescent light signals; a signal processing section which obtains fluorescent light intensity and fluorescence pulse area of the cells from the fluorescent light signals output by the optical detector; and an information processing section configured to detect white blood cells contained in the measurement sample based on the fluorescence pulse area, and detect bacteria contained in the measurement sample based on the fluorescent light intensity.Type: GrantFiled: February 27, 2015Date of Patent: January 24, 2017Assignee: Sysmex CorporationInventors: Masatsugu Ozasa, Mitsumasa Sakamoto, Masanori Kawano
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Patent number: 9417231Abstract: Disclosed is a urine sample analyzing method comprising: flowing a measurement specimen prepared by mixing a urine sample and reagent through a flow cell; irradiating epithelial cells in the measurement specimen flowing through the flow cell with linearly polarized light and thereby producing scattered light; detecting a change of polarization condition of the scattered light produced by each of the epithelial cells; and classifying the epithelial cells into at least two types based on the change of polarization condition.Type: GrantFiled: August 27, 2014Date of Patent: August 16, 2016Assignee: SYSMEX CORPORATIONInventors: Mitsumasa Sakamoto, Masatsugu Ozasa
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Patent number: 9354161Abstract: Disclosed is a sample analyzing method comprising: flowing a measurement specimen prepared by mixing a sample and reagent through a flow cell; irradiating particles in the measurement specimen flowing through the flow cell with linearly polarized light and thereby producing scattered light; detecting a change of polarization condition of the scattered light produced by the particles; and discriminating erythrocytes from crystals in the measurement specimen based on the change of polarization condition.Type: GrantFiled: August 27, 2014Date of Patent: May 31, 2016Assignee: SYSMEX CORPORATIONInventors: Mitsumasa Sakamoto, Masatsugu Ozasa
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Patent number: 9329133Abstract: An apparatus, intended for use in analyzing particles in urine is disclosed, that comprising: a sample distribution section for distributing urine samples to a first aliquot and a second aliquot; a first specimen preparing section for preparing a first specimen for measuring urinary particles, containing at least erythrocytes, by mixing a first stain reagent and the first aliquot; a second specimen preparing section for preparing a second specimen for measuring bacteria by mixing a second stain reagent and the second aliquot; and an optical detecting section comprising a light source for irradiating a light to a specimen being supplied, a scattered light receiving element for detecting scattered light emitted from the specimen, and a fluorescence receiving element for detecting fluorescence emitted from the specimen. A method intended for use in analyzing particles in urine is also disclosed.Type: GrantFiled: August 5, 2013Date of Patent: May 3, 2016Assignee: SYSMEX CORPORATIONInventors: Yousuke Tanaka, Junya Inoue, Masatsugu Ozasa, Yasuyuki Kawashima
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Publication number: 20160054222Abstract: Disclosed is a method for analyzing atypical cells in urine including: mixing urine, a diluent containing a surfactant, and a nucleic acid staining reagent to prepare a measurement specimen; irradiating the measurement specimen with light to detect scattered light and fluorescence light emitted from cells whose nucleic acids are stained; and detecting atypical cells contained in the measurement specimen distinguishably from white blood cells depending on a first characteristic parameter based on the scattered light and a second characteristic parameter based on the fluorescence light.Type: ApplicationFiled: August 20, 2015Publication date: February 25, 2016Inventors: Shota TATEYAMA, Masanori KAWANO, Masatsugu OZASA
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Publication number: 20150369741Abstract: A urine specimen analysis device includes a specimen drawing portion, a sample preparing portion, a measurement portion, and an information processing portion. The specimen drawing portion draws a first aliquot and a second aliquot from a urine specimen. The sample preparing portion prepares a first measurement sample by mixing the first aliquot and a first staining dye that stains red blood cells, and a second measurement sample by mixing the second aliquot and a second staining dye that stains nucleic acids. The measurement portion measures fluorescence emitted from the first measurement sample prepared by the sample preparing portion, and fluorescence emitted from the second measurement sample prepared by the sample preparing portion.Type: ApplicationFiled: August 27, 2015Publication date: December 24, 2015Inventors: Masatsugu OZASA, Kanako NAGAOKA, Akinori KAWAI, Masanori KAWANO
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Publication number: 20150276592Abstract: Disclosed is a urine specimen analyzing method which improves the detection of casts in a urine specimen by flowing a measurement sample containing a urine specimen through a flow cell, irradiating light on the measurement sample flowing through the flow cell, generating a signal waveform indicating a temporal change of intensity of light given off by the measurement sample, and detecting casts distinguishably from mucus threads contained in the urine specimen, based on information related to respective slope at both end sides of the signal waveform corresponding to each formed element contained in the urine specimen.Type: ApplicationFiled: March 30, 2015Publication date: October 1, 2015Inventors: Masatsugu OZASA, Keisuke TSUTSUMIDA, Kenji HANAMURA, Kunio UENO
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Publication number: 20150247802Abstract: Disclosed is a sample analyzer which comprises: a sample preparing section configured to prepare a measurement sample by mixing a sample and a nucleic acid staining reagent; an optical detector configured to irradiate light on cells contained in the measurement sample, receive fluorescent light given off by the irradiated cells, and output fluorescent light signals; a signal processing section which obtains fluorescent light intensity and fluorescence pulse area of the cells from the fluorescent light signals output by the optical detector; and an information processing section configured to detect white blood cells contained in the measurement sample based on the fluorescence pulse area, and detect bacteria contained in the measurement sample based on the fluorescent light intensity.Type: ApplicationFiled: February 27, 2015Publication date: September 3, 2015Inventors: Masatsugu OZASA, Mitsumasa SAKAMOTO, Masanori KAWANO
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Publication number: 20150118706Abstract: Disclosed is a urine sample analyzer for analyzing particles contained in a urine sample and outputting analytical results. The analyzer includes a flow cell that accepts a measurement specimen, the measurement specimen comprising a urine sample mixed with a reagent, a light irradiation unit positioned to irradiate the flowing measurement specimen with light, a light detector that detects light from individual particles in the flowing measurement specimen, and a data processor that receives signal from the light detector, processes the signal to obtain parameter information corresponding to a length of a cell cluster, and classifies fungi in the measurement specimen into groups by using the parameter information.Type: ApplicationFiled: October 27, 2014Publication date: April 30, 2015Inventors: Shota TATEYAMA, Masanori KAWANO, Masatsugu OZASA
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Publication number: 20150060647Abstract: Disclosed is a urine sample analyzing method comprising: flowing a measurement specimen prepared by mixing a urine sample and reagent through a flow cell; irradiating epithelial cells in the measurement specimen flowing through the flow cell with linearly polarized light and thereby producing scattered light; detecting a change of polarization condition of the scattered light produced by each of the epithelial cells; and classifying the epithelial cells into at least two types based on the change of polarization condition.Type: ApplicationFiled: August 27, 2014Publication date: March 5, 2015Inventors: Mitsumasa SAKAMOTO, Masatsugu OZASA
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Publication number: 20150064742Abstract: Disclosed is a sample analyzing method comprising: flowing a measurement specimen prepared by mixing a sample and reagent through a flow cell; irradiating particles in the measurement specimen flowing through the flow cell with linearly polarized light and thereby producing scattered light; detecting a change of polarization condition of the scattered light produced by the particles; and discriminating erythrocytes from crystals in the measurement specimen based on the change of polarization condition.Type: ApplicationFiled: August 27, 2014Publication date: March 5, 2015Inventors: Mitsumasa SAKAMOTO, Masatsugu OZASA
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Patent number: 8772738Abstract: A particle analyzing apparatus, comprising: a flow cell which forms a specimen flow including particles; first and second light sources; an irradiation optical system which applies lights emitted from the first and second light sources so that the lights are applied to the specimen flow; a detector which detects forward scattered light, the forward scattered light being emitted from the first light and scattered by the particle in the specimen flow, and generates a signal according to the detected scattered light; a light blocking member disposed between the flow cell and the detector; a controller which obtains characteristic parameters of the particle based on the signal from the detector; and an imaging device which captures an image of the particle in the specimen flow using the light from the second light source is disclosed. Particle imaging method is also disclosed.Type: GrantFiled: November 22, 2010Date of Patent: July 8, 2014Assignee: Sysmex CorporationInventors: Masatsugu Ozasa, Hiroyuki Kobayashi
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Patent number: 8675196Abstract: An analyzer comprises: a sample stream forming section for forming a sample stream including particles; a light source; an optical fiber bundle formed by a plurality of optical fibers, into which light from the light source enters, and which emits light onto the sample stream; and an imaging device for imaging a particle in the irradiated sample stream.Type: GrantFiled: October 28, 2010Date of Patent: March 18, 2014Assignee: Sysmex CorporationInventor: Masatsugu Ozasa
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Publication number: 20130316444Abstract: An apparatus, intended for use in analyzing particles in urine is disclosed, that comprising: a sample distribution section for distributing urine samples to a first aliquot and a second aliquot; a first specimen preparing section for preparing a first specimen for measuring urinary particles, containing at least erythrocytes, by mixing a first stain reagent and the first aliquot; a second specimen preparing section for preparing a second specimen for measuring bacteria by mixing a second stain reagent and the second aliquot; and an optical detecting section comprising a light source for irradiating a light to a specimen being supplied, a scattered light receiving element for detecting scattered light emitted from the specimen, and a fluorescence receiving element for detecting fluorescence emitted from the specimen. A method intended for use in analyzing particles in urine is also disclosed.Type: ApplicationFiled: August 5, 2013Publication date: November 28, 2013Applicant: SYSMEX CORPORATIONInventors: Yousuke TANAKA, Junya Inoue, Masatsugu Ozasa, Yasuyuki Kawashima
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Patent number: 8501482Abstract: An apparatus, intended for use in analyzing particles in urine is disclosed, that comprising: a sample distribution section for distributing urine samples to a first aliquot and a second aliquot; a first specimen preparing section for preparing a first specimen for measuring urinary particles, containing at least erythrocytes, by mixing a first stain reagent and the first aliquot; a second specimen preparing section for preparing a second specimen for measuring bacteria by mixing a second stain reagent and the second aliquot; and an optical detecting section comprising a light source for irradiating a light to a specimen being supplied, a scattered light receiving element for detecting scattered light emitted from the specimen, and a fluorescence receiving element for detecting fluorescence emitted from the specimen. A method intended for use in analyzing particles in urine is also disclosed.Type: GrantFiled: May 10, 2007Date of Patent: August 6, 2013Assignee: Sysmex CorporationInventors: Yousuke Tanaka, Junya Inoue, Masatsugu Ozasa, Yasuyuki Kawashima