Abstract: An object of the present invention is to provide a hollow fiber membrane with enhanced phosphorus-removing performance without impairing antithrombogenicity in order to inhibit in vivo accumulation of phosphate ions in living body that might cause bone metabolism disorders. The present inventors have found that a hollow fiber membrane having a specific membrane structure and a specific membrane composition possesses a very useful range for inner surface charges of the membrane. More particularly, the inventors have discovered that the above object can be achieved in a limited range in which the zeta potential on the inner surface of a hollow fiber membrane measured under given certain conditions is greater than ?3.0 mV but less than 0 mV. This finding has led to the completion of the present invention.

Abstract: The purpose of the present invention is to provide a medical material which, while retaining high liquid absorbency and styptic properties through gelation of CMC, can maintain shape stability even after absorbing a liquid; which has excellent conformance to the skin; and through which the body surface to which it is to be applied is visible. This medical material is a structure comprising regenerated cellulose fibers including carboxymethyl cellulose fibers in which the degree of substitution of the hydroxyl groups in the glucose units making up the cellulose molecule is at least 0.1 but less than 0.5, wherein the medical material is characterized in that the structure has the form of a woven and/or nonwoven fabric, and when the structure is impregnated with physiological saline, the range of the 10% modulus in both the longitudinal direction and the lateral direction of the structure is 0.2 N/50 mm-5.0 N/50 nm, inclusive.

Abstract: The purpose of the present invention is to provide a medical material which, while retaining high liquid absorbency and styptic properties through gelation of CMC, can maintain shape stability even after absorbing a liquid; which has excellent conformance to the skin; and through which the body surface to which it is to be applied is visible. This medical material is a structure comprising regenerated cellulose fibers including carboxymethyl cellulose fibers in which the degree of substitution of the hydroxyl groups in the glucose units making up the cellulose molecule is at least 0.1 but less than 0.5, wherein the medical material is characterised in that the structure has the form of a woven and/or nonwoven fabric, and when the structure is impregnated with physiological saline, the range of the 10% modulus in both the longitudinal direction and the lateral direction of the structure is 0.2 N/50 mm-5.0 N/50 nm, inclusive.

Abstract: An object of the present invention is to provide a hollow fiber membrane with enhanced phosphorus-removing performance without impairing antithrombogenicity in order to inhibit in vivo accumulation of phosphate ions in living body that might cause bone metabolism disorders. The present inventors have found that a hollow fiber membrane having a specific membrane structure and a specific membrane composition possesses a very useful range for inner surface charges of the membrane. More particularly, the inventors have discovered that the above object can be achieved in a limited range in which the zeta potential on the inner surface of a hollow fiber membrane measured under given certain conditions is greater than ?3.0 mV but less than 0 mV. This finding has led to the completion of the present invention.

Abstract: Provided are a polysulfone type blood-purifying membrane which is improved in blood compatibility and separation properties and less in polyvinyl pyrrolidone eluting in the internal surface of the hollow fiber membrane, as well as a process for producing the same.