Abstract: A low-variation and highly reproducible method for measuring antibody-dependent cellular cytotoxicity activity of an antibody for a dog as the subject of administration is provided. A method for measuring antibody-dependent cellular cytotoxicity activity comprising a step of causing an antibody and cells in which a canine CD16-canine Fc? receptor ? chain fusion protein is expressed in human-derived NK cells to act on canine tumor-derived cells or cells which express a canine tumor antigen and a step of detecting the cell death of the canine tumor-derived cells or the cells which express the canine tumor antigen. Also, the method for measuring antibody-dependent cellular cytotoxicity activity in which the human-derived NK cells are NK-92 cells.

Abstract: The present invention relates to a recording mechanism of a picture and writing transmission and recording system using a ball-point-pen which is pressed to a recording surface with some pressure corresponding to electrical signals obtained from informations of letters, marks and pictures so as to put ink on the surface. The present invention is characterized in that a moving coil, which is connected with the said ball-point-pen and is set in magnetic field so as to be controlled with signal current, is freely movable in the axial direction of the ball-point-pen in a certain range so that the pressure of the ball-point-pen which is given to the recording surface and corresponding to a determined signal current is kept essentially uniform.