Abstract: The present invention provides a composition for treating or preventing skin pigmentation, which contains fibroblasts as an active ingredient, wherein the fibroblasts are those fibroblasts which are less damaged than fibroblasts localized in a site where the skin pigmentation occurs, and the composition is characterized by being intended to be applied to a site where the pigmentation occurs or a dermis tissue around the site.

Abstract: The present invention provides an agent for preventing and/or improving photoaging and/or dermal pigmentation comprising Thujae Semen extract as an active ingredient. The present invention also provides a cosmetic method which includes a step for applying the agent for preventing and/or improving photoaging and/or dermal pigmentation to skin to be treated, and a cosmetic device to be applied in said method.

Abstract: The present invention provides a pigmentation skin model that comprises: a first cell group containing fibroblasts damaged by light irradiation, said first cell group being seeded on a first cell culture substratum; and a second cell group containing melanocytes and keratinocytes, said second cell group being applied onto the first cell group. The present invention also provides a method for producing the pigmentation skin model, and a method for evaluating a factor for treating or preventing pigmentation of the skin, said method comprising using the pigmentation skin model.

Abstract: The present invention provides a composition for treating or preventing skin pigmentation, which contains fibroblasts as an active ingredient, wherein the fibroblasts are those fibroblasts which are less damaged than fibroblasts localized in a site where the skin pigmentation occurs, and the composition is characterized by being intended to be applied to a site where the pigmentation occurs or a dermis tissue around the site.

Abstract: A stratum corneum-collecting adhesive composition includes a hydrophobic component having adhesiveness, and a hydrophilic component that is present in a dispersed state in the hydrophobic component.

Abstract: The present invention provides an antibody specific to a C-terminal domain of a human profilaggrin gene, wherein the C-terminal domain is a peptide comprising the amino acid sequence set forth in SEQ ID NO:1 or a variant thereof, a method for detecting a filaggrin gene mutation using the antibody, and a kit for the detection.

Abstract: A golf club head having a hollow structure includes a face, an internal surface, and an external surface. The face defines a front portion of the golf club head and includes a face surface defining a ball-striking surface. The internal surface includes an internal depression that at least partly extends along the outline of the face surface. The external surface includes an external depression that at least partly extends along the outline of the face surface.

Abstract: A golf club head having a hollow structure includes a face, an internal surface, and an external surface. The face defines a front portion of the golf club head and includes a face surface defining a ball-striking surface. The internal surface includes an internal depression that at least partly extends along the outline of the face surface. The external surface includes an external depression that at least partly extends along the outline of the face surface.

Abstract: A golf club head having a face part, a sole part, a side part, a crown part and a hosel part, all of which surround a hollow part comprises a penetration hole that is provided on the crown part, penetrating the crown part so that the hollow part is connected with an outer atmosphere of the golf club head and a non-metal cover that is provided over the penetration hole. A recess part, which forms a recess, is provided on a surface of the non-metal cover.

Abstract: A golf club head having a face part, a sole part, a side part, a crown part and a hosel part, all of which surround a hollow part comprises a penetration hole that is provided on the crown part, penetrating the crown part so that the hollow part is connected with an outer atmosphere of the golf club head and a non-metal cover that is provided over the penetration hole. A recess part, which forms a recess, is provided on a surface of the non-metal cover.

Abstract: The present invention provides an antibody specific to a C-terminal domain of a human profilaggrin gene, wherein the C-terminal domain is a peptide comprising the amino acid sequence set forth in SEQ ID NO:1 or a variant thereof, a method for detecting a filaggrin gene mutation using the antibody, and a kit for the detection.