Patents by Inventor Masayasu TOYOMOTO

Masayasu TOYOMOTO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ALPHA-2 ADRENERGIC RECEPTOR ANTAGONIST
    Publication number: 20230372309
    Abstract: Provided in one aspect is a pharmaceutical composition for analgesia. The present disclosure relates to a pharmaceutical composition for analgesia that contains an a2 adrenergic receptor antagonist as an active ingredient. In one or more embodiments, the pharmaceutical composition according to the present disclosure is a composition for analgesia through inhibition of an a2 adrenergic receptor, or a composition for analgesia through inhibition of an a2B adrenergic receptor.
    Type: Application
    Filed: September 22, 2021
    Publication date: November 23, 2023
    Applicant: Kyoto University
    Inventors: Masatoshi Hagiwara, Masayasu Toyomoto
  • PHARMACEUTICAL COMPOSITION FOR INDUCING PROGRAMMED CELL DEATH IN CANCER CELLS
    Publication number: 20200188382
    Abstract: A method for inducing programmed cell death in cancer cells and a pharmaceutical composition therefor are provided. Provided is a method for inducing programmed cell death in cancer cells, the method including enhancing production of nitric oxide in cancer cells. Provided is a pharmaceutical composition for inducing programmed cell death in cancer cells, the pharmaceutical composition containing, as an active component, a compound that enhances production of nitric oxide in cancer cells. Provided is use of a compound that enhances production of nitric oxide in cancer cells, in a method for preventing, improving, suppressing progression of, and/or treating cancers.
    Type: Application
    Filed: October 31, 2017
    Publication date: June 18, 2020
    Applicant: KYOTO UNIVERSITY
    Inventors: Masatoshi HAGIWARA, Masayasu TOYOMOTO, Takamitsu HOSOYA, Suguru YOSHIDA
  • COMPOSITION HAVING COMPOUND ACCELERATING PHOSPHORYLATION OF AMPK AS EFFECTIVE COMPONENT
    Publication number: 20180290979
    Abstract: Provided is a composition that can be used for an organ preservation solution or perfusate. Alternatively, provided is a composition for prolonging the survival of normal cells and/or a composition for inhibiting the survival of cancer cells. In one or more embodiments, a composition containing, as an active component, a compound that enhances phosphorylation of AMPK (AMP-activated protein kinase). Said composition is one that can prolong the survival of cells (especially, normal cells). Furthermore, said composition is one that can inhibit the survival of cancer cells.
    Type: Application
    Filed: April 28, 2016
    Publication date: October 11, 2018
    Applicant: Kyoto University
    Inventors: Masatoshi HAGIWARA, Masayasu TOYOMOTO, Isao KII, Takamitsu HOSOYA, Suguru YOSHIDA
  • Pain-related compound and medical composition
    Patent number: 9745275
    Abstract: Provided is a pain-related compound, a pain-related pharmaceutical composition, and use of the same. Provided in one or more embodiments is a compound represented by Formula (I), a prodrug of the same, or a pharmaceutically permissible salt of any of the same.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: August 29, 2017
    Assignees: KYOTO UNIVERSITY, KAGOSHIMA UNIVERSITY
    Inventors: Masatoshi Hagiwara, Masayasu Toyomoto, Takamitsu Hosoya, Suguru Yoshida, Takashi Kurihara
  • PAIN-RELATED COMPOUND AND MEDICAL COMPOSITION
    Publication number: 20170029389
    Abstract: Provided is a pain-related compound, a pain-related pharmaceutical composition, and use of the same. Provided in one or more embodiments is a compound represented by Formula (I), a prodrug of the same, or a pharmaceutically permissible salt of any of the same.
    Type: Application
    Filed: December 18, 2014
    Publication date: February 2, 2017
    Applicants: KYOTO UNIVERSITY, NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY, KAGOSHIMA UNIVERSITY
    Inventors: Masatoshi HAGIWARA, Masayasu TOYOMOTO, Takamitsu HOSOYA, Suguru YOSHIDA, Takashi KURIHARA