Patents by Inventor Masayo Sakata

Masayo Sakata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10987651
    Abstract: Means for removing endotoxin is provided. Endotoxin is removed by contacting an endotoxin adsorbent including a cellulose nanofiber having an amino group with a liquid containing endotoxin.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: April 27, 2021
    Assignees: National University Corporation Kumamoto University, Nagase ChemteX Corporation
    Inventors: Masayo Sakata, Towako Sakamoto, Daisuke Nakamura, Yuki Maeda
  • Patent number: 10155217
    Abstract: A means for selectively removing ET under coexistence of a substance showing a negative charge, such as nucleic acid is described. Endotoxin is selectively removed by bringing a polymer obtained by crosslinking cyclodextrin with an isocyanate-based crosslinking agent in contact with a solution containing endotoxin and the substance showing the negative charge such as nucleic acid.
    Type: Grant
    Filed: October 4, 2016
    Date of Patent: December 18, 2018
    Assignees: NATIONAL UNIVERSITY CORPORATION KUMAMOTO, JNC CORPORATION
    Inventors: Masayo Sakata, Masami Todokoro
  • Publication number: 20180178192
    Abstract: Means for removing endotoxin is provided. Endotoxin is removed by contacting an endotoxin adsorbent including a cellulose nanofiber having an amino group with a liquid containing endotoxin.
    Type: Application
    Filed: July 29, 2016
    Publication date: June 28, 2018
    Inventors: Masayo SAKATA, Towako SAKAMOTO, Daisuke NAKAMURA, Yuki MAEDA
  • Publication number: 20170021332
    Abstract: A means for selectively removing ET under coexistence of a substance showing a negative charge, such as nucleic acid is described. Endotoxin is selectively removed by bringing a polymer obtained by crosslinking cyclodextrin with an isocyanate-based crosslinking agent in contact with a solution containing endotoxin and the substance showing the negative charge such as nucleic acid.
    Type: Application
    Filed: October 4, 2016
    Publication date: January 26, 2017
    Applicants: NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY, JNC CORPORATION
    Inventors: MASAYO SAKATA, MASAMI TODOKORO
  • Patent number: 9505850
    Abstract: A means for selectively removing ET under coexistence of a substance showing a negative charge, such as nucleic acid is described. Endotoxin is selectively removed by bringing a polymer obtained by crosslinking cyclodextrin with an isocyanate-based crosslinking agent in contact with a solution containing endotoxin and the substance showing the negative charge such as nucleic acid.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: November 29, 2016
    Assignees: NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY, JNC CORPORATION
    Inventors: Masayo Sakata, Masami Todokoro
  • Publication number: 20150112050
    Abstract: A means for selectively removing ET under coexistence of a substance showing a negative charge, such as nucleic acid is described. Endotoxin is selectively removed by bringing a polymer obtained by crosslinking cyclodextrin with an isocyanate-based crosslinking agent in contact with a solution containing endotoxin and the substance showing the negative charge such as nucleic acid.
    Type: Application
    Filed: May 29, 2013
    Publication date: April 23, 2015
    Inventors: Masayo Sakata, Masami Todokoro
  • Patent number: 7563580
    Abstract: A nucleic acid adsorbent in which a polymer having a constitutional unit represented by the following formula (I) is immobilized on a water-insoluble carrier is used as a nucleic acid adsorbent capable of selectively and efficiently adsorbing nucleic acids from complex mixtures, such as cell extract, wherein R1 represents hydrogen, fluoride, or methyl; R2 and R3 each independently represent alkyl of 1 to 6 carbon atoms; A is —NH— or —O—; and B represents alkylene of 2 to 18 carbon atoms. Nucleic acids are recovered from cell extract by allowing them to be adsorbed to the nucleic acid adsorbent by mixing this nucleic acid adsorbent with cell extract, removing the nucleic acids from the cell extract by separating the adsorbent therefrom, and dissociating the nucleic acids from the nucleic acid adsorbent by treating the separated nucleic acid adsorbent with alkali.
    Type: Grant
    Filed: February 27, 2008
    Date of Patent: July 21, 2009
    Assignees: Chisso Corporation, Kumamoto University
    Inventors: Chuichi Hirayama, Masayo Sakata, Masami Todokoro, Minoru Nakayama
  • Publication number: 20080227969
    Abstract: A nucleic acid adsorbent in which a polymer having a constitutional unit represented by the following formula (I) is immobilized on a water-insoluble carrier is used as a nucleic acid adsorbent capable of selectively and efficiently adsorbing nucleic acids from complex mixtures, such as cell extract, wherein R1 represents hydrogen, fluoride, or methyl; R2 and R3 each independently represent alkyl of 1 to 6 carbon atoms; A is —NH— or —O—; and B represents alkylene of 2 to 18 carbon atoms. Nucleic acids are recovered from cell extract by allowing them to be adsorbed to the nucleic acid adsorbent by mixing this nucleic acid adsorbent with cell extract, removing the nucleic acids from the cell extract by separating the adsorbent therefrom, and dissociating the nucleic acids from the nucleic acid adsorbent by treating the separated nucleic acid adsorbent with alkali.
    Type: Application
    Filed: February 27, 2008
    Publication date: September 18, 2008
    Inventors: Chuichi Hirayama, Masayo Sakata, Masami Todokoro, Minoru Nakayama
  • Patent number: 7358050
    Abstract: A nucleic acid adsorbent in which a polymer having a constitutional unit represented by the following formula (I) is immobilized on a water-insoluble carrier is used as a nucleic acid adsorbent capable of selectively and efficiently adsorbing nucleic acids from complex mixtures, such as cell extract, wherein R1 represents hydrogen, fluoride, or methyl; R2 and R3 each independently represent alkyl of 1 to 6 carbon atoms; A is —NH— or —O—; and B represents alkylene of 2 to 18 carbon atoms. Nucleic acids are recovered from cell extract by allowing them to be adsorbed to the nucleic acid adsorbent by mixing this nucleic acid adsorbent with cell extract, removing the nucleic acids from the cell extract by separating the adsorbent therefrom, and dissociating the nucleic acids from the nucleic acid adsorbent by treating the separated nucleic acid adsorbent with alkali.
    Type: Grant
    Filed: August 31, 2005
    Date of Patent: April 15, 2008
    Assignees: Chisso Corporation, Kumamoto University
    Inventors: Chuichi Hirayama, Masayo Sakata, Masami Todokoro, Minoru Nakayama
  • Publication number: 20060073499
    Abstract: A nucleic acid adsorbent in which a polymer having a constitutional unit represented by the following formula (I) is immobilized on a water-insoluble carrier is used as a nucleic acid adsorbent capable of selectively and efficiently adsorbing nucleic acids from complex mixtures, such as cell extract, wherein R1 represents hydrogen, fluoride, or methyl; R2 and R3 each independently represent alkyl of 1 to 6 carbon atoms; A is —NH— or —O—; and B represents alkylene of 2 to 18 carbon atoms. Nucleic acids are recovered from cell extract by allowing them to be adsorbed to the nucleic acid adsorbent by mixing this nucleic acid adsorbent with cell extract, removing the nucleic acids from the cell extract by separating the adsorbent therefrom, and dissociating the nucleic acids from the nucleic acid adsorbent by treating the separated nucleic acid adsorbent with alkali.
    Type: Application
    Filed: August 31, 2005
    Publication date: April 6, 2006
    Inventors: Chuichi Hirayama, Masayo Sakata, Masami Todokoro, Minoru Nakayama
  • Patent number: 6699386
    Abstract: This invention provides an adsorbent having a high ability to adsorb endotoxin selectively and a method of adsorbing endotoxin. The adsorbent comprises a basic substance bonded to a base material by means of a crosslinking agent.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: March 2, 2004
    Assignee: Chisso Corporation
    Inventors: Masami Todokoro, Chuichi Hirayama, Masashi Kunitake, Masayo Sakata
  • Publication number: 20020130082
    Abstract: This invention provides an adsorbent having a high ability to adsorb endotoxin selectively and a method of adsorbing endotoxin. The adsorbent comprises a basic substance bonded to a base material by means of a crosslinking agent.
    Type: Application
    Filed: March 1, 2002
    Publication date: September 19, 2002
    Applicant: Chisso Corporation
    Inventors: Masami Todokoro, Chuichi Hirayama, Masashi Kunitake, Masayo Sakata