Patents by Inventor Masayoshi Nanba

Masayoshi Nanba has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human derived immortalized liver cell line
    Patent number: 7186553
    Abstract: The present invention relates to a new immortalized hepatocyte culture of human (preferably human fetal) normal cell origin. The immortalized hepatocyte culture of human normal cell origin of the present invention is useful in, for example, screening for compounds or salts thereof having therapeutic/preventive effects on hepatic insufficiency.
    Type: Grant
    Filed: April 27, 1999
    Date of Patent: March 6, 2007
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Masayoshi Nanba, Kenichi Fukaya, Satoru Asahi, Sumie Yoshitomi
  • Human cell line showing stable expression of cytochromes P450
    Patent number: 6756229
    Abstract: This invention relates to cell lines that are obtained using cultured cell lines derived from human liver as a host and that stably express a number of human cytochromes P450. The human liver-derived cultured cell lines of the present invention are useful in, for example, analyzing an enzyme participating in the metabolism of xenobiotics or endogenous substrates, because of their stable expression of human cytochromes P450 CYP1A1, 1A2, 2A6, 2B6, 2C8, 2C9, 2C9, 2D6, and 3A4.
    Type: Grant
    Filed: October 25, 2001
    Date of Patent: June 29, 2004
    Assignees: Takeda Chemical Industries, Ltd.
    Inventors: Masayoshi Nanba, Satoru Asahi, Sumie Yoshitomi, Keiko Ikemoto