Abstract: An object of the present invention is to provide a microorganism which has a high ability of producing docosahexaenoic acid. The present invention provides a Thraustochytrium strain which has an ability of producing docosahexaenoic acid, and use thereof.

Abstract: A method for preparing an aqueous composition for sterilization, which comprises the step of mixing an acylimidazole represented by the general formula (II): wherein R represents a substituted or unsubstituted C1-C20 alkyl group, or a substituted or unsubstituted C6-C30 aryl group, with an aqueous solution containing a hydrogen peroxide source to produce a corresponding peroxycarboxylic acid. An aqueous composition for sterilization suitable for sterilization of medical apparatuses such as endoscopes, which can be safely and quickly prepared upon use, and a method for preparing the same are provided.

Abstract: To down size a distortion-correcting circuit. In the case of a distortion-correcting circuit 1, a basic-wave-amplifying section 10 and a distortion-extracting section 20 have the same circuit configuration. Therefore, the basic-wave-amplifying section 10 and the distortion-extracting section 20 have almost equal input impedance and output impedance and make it possible to distribute and synthesize signal powers without using any power distributor or any power synthesizer. Moreover, because the distortion-correcting circuit 1 is constituted by only a transistor, a resistance, a capacitor, or an inductor, it is easy to downsize the circuit 1 and constitute the circuit 1 into an integrated circuit. Therefore, a characteristic of the basic-wave-amplifying section 10 and that of the distortion-extracting section 20 are further similar to each other and it is possible to more properly distribute or synthesize signal powers without using any power distributor or any power synthesizer.

Abstract: A near infrared fluorescent contrast agent which is excellent in permeability in a living tissue and enables specific imaging of tumor and/or blood vessel, comprising a compound represented by formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R7, and R8 represent a C1-C10 alkyl group or the like; R3, R4, R5, R6, R9, R10, R11, and R12 represent a hydrogen atom, a C1-C6 alkyl group, an aryl group or the like; X1 and X2 represent a C1-C15 alkyl group or an aryl group and X1 and X2 in total have 0 to 4 carboxyl groups; m1, m2, and m3 represents 0 or 1; L1 to L7 independently represent a methine group; M represents a hydrogen atom, a metal, or a quaternary ammonium salt; and n represents an integer of 1 to 7 necessary for neutralizing charge.

Abstract: A compound represented by the following formula (I) or a salt thereof: wherein R1 and R2 represent an alkyl group or an aryl group; R3 to R6 represent hydrogen atom, an alkyl group, an aryl group, a heteroaryl group, a halogen atom, cyano group, carboxyl group or sulfo group; X1 and X2 represent an alkyl group having 1 to 15 carbon atoms or an aryl group, and the total number of carboxyl groups existing in X1 and X2 is 4 or less; m1 to m3 represents 0 or 1; L1 to L7 represent a methine group; M represents hydrogen atom, a metal or a quaternary ammonium salt; Y represents nonmetallic elements required to form a 5- to 10-membered heterocyclic ring; and n represents an integer of 1 to 7 required to neutralize charge, which is useful for manufacture of silver halide photographic light-sensitive materials.

Abstract: A compound represented by the general formula (I) or a salt thereof [wherein R1, R2, R4, and R5 represent an alkyl group or an aryl group, and R1 and R2 and/or R4 and R5 may bind to each other to form a ring; R3 represents hydrogen atom or sulfo group; R6, R7, R8, and R9 represent hydrogen atom, a halogen atom, an alkyl group, an alkoxyl group, an amino group, nitro group or cyano group; X1 and X2 represent an alkyl group or an aryl group; m1 to m3 represents 0 or 1; L1 to L7 represent a methine group, and when two or more of methine groups among the aforementioned methine groups have a substituent, the substituents may bind to each other to form a ring; M represents hydrogen atom, a metal or a quaternary ammonium salt; and n represents an integer of 1 to 7 required to neutralize a charge].

Abstract: A benzimidazole compound or a salt thereof which has an inhibitory action of foaming of macrophages and is useful as an active ingredient of a medicament for preventive and/or therapeutic treatment of arteriosclerosis, which is represented by the formula (I): wherein R1 represents a hydrogen atom, a halogen atom, a lower alkyl group, or a lower alkoxy group; R2 represents a hydrogen atom, an alkyl group, or an acyl group; R3 represents a functional group on the ring; A represents O or CH2 or CH that forms a double bond with an adjacent carbon atom; L represents a C4-C8 alkylene group or an ethyleneoxy linking group represented by (CH2CH2O)nCH2CH2 wherein n represents 1 or 2; X represents O, S or methylene group; and m represents 0 or 1.

Abstract: A benzimidazole compound or a salt thereof which has an inhibitory action of forming of macrophages and is useful as an active ingredient of an orally available medicament for preventive and/or therapeutic treatment of arteriosclerosis, which is represented by the formula (I): wherein, R1 represents one or more functional groups on the benzene ring selected from the group consisting of hydrogen atom, a halogen atom, a lower alkyl group and a lower alkoxy group; R2 represents hydrogen atom, an alkyl group or an acyl group; L represents a C4-C8 alkylene group or an ethyleneoxy linking group represented as (CH2CH2O)nCH2CH2 wherein n represents 1 or 2; X represents O or NH; Y represents S or a single bond; and Q represents a 5- or 6-membered heterocyclic group which may have a functional group on the ring.

Abstract: There is provided a method of managing production quantity that includes determining a standard inventory quantity of products to be stocked in the single delivery center for a time of at least one predetermined cycle ahead based on a shipment record of the single delivery center, and determining a total assembly quantity of products to be assembled by the at least one factory for a time of at least one predetermined cycle ahead based on the determined standard inventory quantity of the single delivery center and an actual inventory quantity of the at least one factory.

Abstract: An object of the present invention is to provide a microorganism which has a high ability of producing docosahexaenoic acid. The present invention provides a Thraustochytrium strain which has an ability of producing docosahexaenoic acid, and use thereof.

Abstract: A compound represented by the following formula (I) or a salt thereof: 1

Abstract: To down size a distortion-correcting circuit. In the case of a distortion-correcting circuit 1, a basic-wave-amplifying section 10 and a distortion-extracting section 20 have the same circuit configuration. Therefore, the basic-wave-amplifying section 10 and the distortion-extracting section 20 have almost equal input impedance and output impedance and make it possible to distribute and synthesize signal powers without using any power distributor or any power synthesizer. Moreover, because the distortion-correcting circuit 1 is constituted by only a transistor, a resistance, a capacitor, or an inductor, it is easy to downsize the circuit 1 and constitute the circuit 1 into an integrated circuit. Therefore, a characteristic of the basic-wave-amplifying section 10 and that of the distortion-extracting section 20 are further similar to each other and it is possible to more properly distribute or synthesize signal powers without using any power distributor or any power synthesizer.

Abstract: A benzimidazole compound or a salt thereof which has an inhibitory action of forming of macrophages and is useful as an active ingredient of a medicament for preventive and/or therapeutic treatment of arteriosclerosis, which is represented by the formula (I): wherein, R1 represents a functional group on the benzene ring selected from the group consisting of hydrogen atom, a halogen atom, a lower alkyl group and a lower alkoxy group; R2 represents hydrogen atom, an alkyl group or an acyl group; R3 represents a functional group on the ring containing the nitrogen atom and Z; Z represents a divalent group which forms a 5- or 6-membered ring; L represents a C4-C8 alkylene group or an ethyleneoxy linking group represented by (CH2CH2O)nCH2CH2 wherein n represents 1 or 2; and X represents O or S.

Abstract: Disclosed is an integrated circuit device. According to the present invention, an integrated circuit device comprises: a high frequency electronic circuit having a first enhancement transistor, to the gate of which, at least, a bias voltage is applied; and a bias circuit, including a second enhancement transistor formed on a substrate on which the first enhancement transistor is formed, and first, second and third resistors connected in series between a positive power source and a power source ground, in which a connection point of the first and the second resistors is connected to a drain of the second enhancement transistor, a connection point of the second and the third resistors is connected to a gate of the second enhancement transistor, and voltages at the connection point of the second resistor and the third resistor or at a terminal which is closer to the power source ground is applied as a bias voltage to the high frequency electronic circuit.

Abstract: The present invention relates to a double-balanced mixer circuit. The double-balanced mixer circuit consists of a first differential circuit formed of a first transistor and a second transistor connected differentially to each other for receiving a first input signal; and a second differential circuit formed of a third transistor and a fourth transistor connected differentially to each other for receiving a second input signal; either the junction of the drain or collector of the first transistor and the drain or collector of the third transistor or the junction of the drain or collector of the second transistor and the drain or collector of the fourth transistor producing an output signal having frequency information on the sum of the first input signal and the second input signal or the difference between them. The double-balanced mixer circuit is used suitably as a frequency converter which is used at the high-frequency section in a mobile communications equipment such as portable telephones.

Abstract: A pharmaceutical composition for treatment of cancer in an animal comprising:(A) a therapeutically effective amount of at least one compound selected from the group consisting of compounds represented by the General Formula (I). ##STR1## wherein Z.sub.1 and Z.sub.2, which may be the same or different, each represents an atomic group necessary to form a 5- or 6-membered ring;R.sub.1, R.sub.2 and R.sub.3, which may be the same or different, each represents an alkyl group or an aryl group;L.sub.1 and L.sub.2 each represents a methine group or a substituted methine group;X represents a pharmaceutically acceptable anion;k represents a number necessary for electrical charge balance;n represents 0 or 1; and(B) a pharmaceutically acceptable carrier or diluent.

Abstract: There are provided methine compounds having the following structure and their analogs, with a high solubility and are usefull as an active ingredient for pharmaceutical composition for treatment of cancer: ##STR1##

Abstract: A methine compound represented by the following formula (I): ##STR1## wherein Z.sub.1 and Z.sub.2 each represent a non-metallic atomic group necessitated for forming a five-membered or six-membered, nitrogen-containing heterocyclic ring, R.sub.1 and R.sub.2 each represent an alkyl group, X represents an inorganic anion, k represents a number necessitated for adjusting the electric charge of the molecule to zero, and n represents 0 or 1; with the proviso that when n is 1, the five-membered or six-membered, nitrogen-containing heterocyclic ring formed by Z.sub.2 is cationic, k is not zero and X represents chloride ion. The compound is useful as a spectral sensitizing dye and an antitumor agent.