Abstract: A sensor interface circuit includes: an RF switch having a control node; a bias circuit electrically connected to the control node and applying, to the control node, a voltage at a first level or a second level corresponding to a linear region of a reflection characteristic; a first variable oscillation circuit electrically connectable to a first sensor; a second variable oscillation circuit electrically connectable to a second sensor; and a difference circuit electrically connected between the first variable oscillation circuit and the bias circuit, and between the second variable oscillation circuit and the bias circuit.

Abstract: Provided is a computer-implemented method including acquiring a first pieces of observation data that include a position of a mobile object and a received signal strength of a wireless signal observed by the mobile object; and correcting each position of the mobile object included in each piece of observation data of the first pieces of observation data using one position of the mobile object at a time before the received signal strength included in the piece of observation data is observed.

Abstract: An image processing device includes a determination unit configured to determine a type of autophagy induced in a cell, based on information indicative of autophagic activity in the cell present in a cell image in which the cell is image captured and based on information indicative of congestion of molecules in the cell present in the cell image.

Abstract: An image processing device includes a determination unit configured to determine a type of autophagy induced in a cell, based on information indicative of autophagic activity in the cell present in a cell image in which the cell is image captured and based on information indicative of congestion of molecules in the cell present in the cell image.

Abstract: Provided is a computer-implemented method including acquiring a first pieces of observation data that include a position of a mobile object and a received signal strength of a wireless signal observed by the mobile object; and correcting each position of the mobile object included in each piece of observation data of the first pieces of observation data using one position of the mobile object at a time before the received signal strength included in the piece of observation data is observed.

Abstract: A placement of a set of devices in an environment is evaluated. At least a plurality of neighboring locations is selected for a target location in the environment. A probability of an estimated location conditioned on the target location is calculated for each of at least the plurality of neighboring locations as the estimated location by using an observation model for obtaining a set of observation values given a location under the placement. An evaluation metric is computed by using the probability calculated for each of at least the plurality of neighboring locations.

Abstract: The object of the present invention is to provide a method for incorporating an arbitrary protein, lipid, carbohydrate, or nucleic acid into an exosome. The object can be solved by a method for preparing an exosome, comprising the steps of: (a) adding a biological toxin having a perforating activity to a medium containing cells and incubating the mixture, (b) adding ATP and incubating the mixture, and (c) adding a medium containing calcium ion and incubating the mixture.

Abstract: An analysis device configured to analyze a correlation between feature values in a cell in response to a stimulus includes: a cell-image acquiring unit configured to acquire a plurality of cell images in which the cell that is stimulated is captured; a feature value calculating unit configured to calculate a feature value for constituent elements that form the cell, based on the plurality of cell images acquired by the cell-image acquiring unit; a correlation calculating unit configured to use the feature value calculated by the feature value calculating unit and to calculate correlations between the constituent elements; a correlation selecting unit configured to select a first correlation from the correlations calculated by the correlation calculating unit; and an image selecting unit configured to select a first cell image from the plurality of cell images that are captured, based on the first correlation that is selected.

Abstract: A method for identifying a patient with malignant tumor which can be expected to benefit more from an immune checkpoint inhibitor, and agent for suppressing the progression of, suppressing the recurrence of, and/or treating malignant tumor, being prescribed based thereon, comprising use of a combination of two sets of evaluation items and specific condition defined by each of combination thereof.

Abstract: An analysis device configured to analyze an attribute of a correlation between responses with respect to a stimulus to a first subcellular component that is a subcellular component of a cell and a second subcellular component different from the first subcellular component, the analysis device including an attribute analysis unit that analyzes the attribute of the correlation between the first subcellular component and the second subcellular component based on a first change in a feature value of the second subcellular component with respect to the stimulus in a state a function of the first subcellular component is suppressed and a second change in a feature value of the second subcellular component with respect to the stimulus in a state the function of the first subcellular component is not suppressed.

Abstract: An image-processing device including: a determination unit that determines a captured image on the basis of a ratio of cells and a distribution of the cells in the captured image acquired by imaging a sample including cells; and an area setting unit that sets an area used for analyzing the cells of the sample on the basis of a result of the determination acquired by the determination unit.

Abstract: A placement of a set of devices in an environment is evaluated. At least a plurality of neighboring locations is selected for a target location in the environment. A probability of an estimated location conditioned on the target location is calculated for each of at least the plurality of neighboring locations as the estimated location by using an observation model for obtaining a set of observation values given a location under the placement. An evaluation metric is computed by using the probability calculated for each of at least the plurality of neighboring locations.

Abstract: Provided is a computer-implemented method including acquiring a first pieces of observation data that include a position of a mobile object and a received signal strength of a wireless signal observed by the mobile object; and correcting each position of the mobile object included in each piece of observation data of the first pieces of observation data using one position of the mobile object at a time before the received signal strength included in the piece of observation data is observed.

Abstract: The object of the present invention is to provide a method for identifying a patient with malignant tumor on which the effect of an immune checkpoint inhibitor can be more expected, and agents for suppressing the progression of, suppressing the recurrence of, and/or treating malignant tumor, characterized by prescriptions based on those. The present invention can provide agents for suppressing the progression of, suppressing the recurrence of, and/or treating malignant tumor, characterized by prescriptions based on identifying a patient with a malignant tumor on which the effect of an immune checkpoint inhibitor can be more expected, by analyzing the evaluation items consisting of combinations such as the PD-1 expression intensity, the percentage of the number of PD-1 expressing cells and the like in Treg cells and CD8+ T cells in tumor tissue or blood.

Abstract: Provided is a computer-implemented method including acquiring a first pieces of observation data that include a position of a mobile object and a received signal strength of a wireless signal observed by the mobile object; and correcting each position of the mobile object included in each piece of observation data of the first pieces of observation data using one position of the mobile object at a time before the received signal strength included in the piece of observation data is observed.

Abstract: An analysis device includes: a cell image acquisition unit that acquires a plurality of cell images in which a stimulated cell has been captured; a feature value calculation unit that calculates a feature value for each of first and second constituent elements constituting the cell, from the cell images acquired by the cell image acquisition unit; a correlation calculation unit that calculates correlations between first feature values and between second feature values in the first and second constituent elements calculated by the feature value calculation unit; a correlation extraction unit that extracts the correlation between the first feature values by selecting the first feature values with respect to the correlations between the feature values in the first and second constituent elements calculated by the correlation calculation unit; and a display unit that displays the correlation between the first feature values extracted by the correlation extraction unit.

Abstract: A method for generating route network data for movement includes calculating a movable area in a place for a target type of movement using a space model of the place and an object model for the target type. The method also includes building network structure for route network data of the place using the movable area for the target type, in which the network structure includes a plurality of nodes and a plurality of links representing routes within the place. The method further includes updating the network structure by shifting a node to orient a link connected to the node toward any one of predetermined directions under a condition relating to an initial position of the node.

Abstract: The object of the present invention is to provide a method for incorporating an arbitrary protein, lipid, carbohydrate, or nucleic acid into an exosome. The object can be solved by a method for preparing an exosome, comprising the steps of: (a) adding a biological toxin having a perforating activity to a medium containing cells and incubating the mixture, (b) adding ATP and incubating the mixture, and (c) adding a medium containing calcium ion and incubating the mixture.

Abstract: A computer-implemented method includes acquiring a plurality of received signal strength indicators obtained by a target wireless terminal which observes a plurality of wireless signals transmitted from a plurality of transmitters, selecting a set of received signal strength indicators which is a portion of the plurality of received signal strength indicators, acquiring a set of reference received signal strength indicators corresponding to the set of received signal strength indicators, from a database of a plurality of reference received signal strength indicators that serve as a reference for the plurality of received signal strength indicators, and estimating a received signal strength indicator offset of the target wireless terminal, based on the set of received signal strength indicators and the set of reference received signal strength indicators.

Abstract: An analysis device includes an acquisition unit configured to acquire an image of a cell and an identification unit configured to identify elements that are identifiable on the basis of the image of cell acquired by the acquisition unit. Characteristic quantities of the elements identified by the identification unit are calculated, a correlation between the characteristic quantities is calculated on the basis of the calculated characteristic quantities of the elements, and a correlation between the elements is calculated on the basis of the calculated correlation between the characteristic quantities.