Abstract: An information processing apparatus includes management circuitry that manages three-dimensional data obtained by a scanner in the order of obtaining, display controller circuitry that controls a display to show a three-dimensional image generated from combined data generated by combining a plurality of pieces of three-dimensional data, and input circuitry that accepts an operation by a user. When the input circuitry accepts an operation to select three-dimensional data, the management circuitry sets, from the selected three-dimensional data of last obtained three-dimensional data, data to be deleted. The display controller circuitry controls the display to show a three-dimensional image modified to exclude the data to be deleted.

Abstract: A magnifying glass captures an image of a tooth by a plurality of cameras for observation. The plurality of cameras includes a narrow range camera capturing a narrow range image of the tooth and a wide range camera capturing a wide range image of the tooth. The magnifying glass includes a three-dimensional position calculator detecting a three-dimensional position of at least the tooth based on the wide range image; a blur correction processor correcting a blur of the narrow range image, based on a change in a three-dimensional positional relationship between the tooth, the three-dimensional position of which has been detected by the three-dimensional position detector, and the narrow range camera; and an image display portion displaying at least the narrow range image having the blur corrected.

Abstract: An isolated RNA molecule includes an artificial microRNA precursor comprising in the 5??3? direction: a first terminal oligonucleotide consisting of AGGCCR (SEQ ID NO: 1) or a nucleotide sequence in which one to three nucleotides in SEQ ID NO: 1 are substituted; a passenger strand oligonucleotide; a first central oligonucleotide consisting of CYG (SEQ ID NO: 2); a second central oligonucleotide consisting of a nucleotide sequence having at least 70% homology with UUGAAUAKAAAU (SEQ ID NO: 3); a third central oligonucleotide consisting of YGG (SEQ ID NO: 4); a guide strand oligonucleotide; and a second terminal oligonucleotide consisting of UGGAYYK (SEQ ID NO: 5) or a nucleotide sequence in which one to three nucleotides in SEQ ID NO: 5 are substituted.

Abstract: An information processing apparatus includes management circuitry that manages three-dimensional data obtained by a scanner in the order of obtaining, display controller circuitry that controls a display to show a three-dimensional image generated from combined data generated by combining a plurality of pieces of three-dimensional data, and input circuitry that accepts an operation by a user. When the input circuitry accepts an operation to select three-dimensional data, the management circuitry sets, from the selected three-dimensional data of last obtained three-dimensional data, data to be deleted. The display controller circuitry controls the display to show a three-dimensional image modified to exclude the data to be deleted.

Abstract: A magnifying glass captures an image of a tooth by a plurality of cameras for observation. The plurality of cameras includes a narrow range camera capturing an image of the tooth in a narrow image capturing range and a wide range camera capturing an image of the tooth in a wide image capturing range. The magnifying glass includes a three-dimensional position calculator detecting a three-dimensional position of at least the tooth based on the wide range image captured by the wide range camera; a blur correction processor correcting a blur of the narrow range image captured by the narrow range camera, based on a change in a three-dimensional positional relationship between the tooth, the three-dimensional position of which has been detected by the three-dimensional position detector, and the narrow range camera; and an image display portion displaying at least the narrow range image having the blur corrected.

Abstract: An intraoral three-dimensional measuring method, comprising: acquiring, with a handy scanner, wide range three-dimensional measurement information on a three-dimensional shape measured on a wide range in a desirable measurement range in an intraoral space; acquiring, with the handy scanner, a plurality of pieces of narrow range three-dimensional measurement information each on a three-dimensional shape measured on a narrow range narrower than the wide range in the measurement range; and locating, with a controller, the plurality of pieces of narrow range three-dimensional measurement information based on the wide range three-dimensional measurement information by use of, as a synthesis reference, intra-measurement range position information common to the wide range three-dimensional measurement information and each of the plurality of pieces of narrow range three-dimensional measurement information, and creating synthetic three-dimensional information on the measurement range.

Abstract: An intraoral three-dimensional measuring method, comprising: acquiring, with a handy scanner, wide range three-dimensional measurement information on a three-dimensional shape measured on a wide range in a desirable measurement range in an intraoral space; acquiring, with the handy scanner, a plurality of pieces of narrow range three-dimensional measurement information each on a three-dimensional shape measured on a narrow range narrower than the wide range in the measurement range; and locating, with a controller, the plurality of pieces of narrow range three-dimensional measurement information based on the wide range three-dimensional measurement information by use of, as a synthesis reference, intra-measurement range position information common to the wide range three-dimensional measurement information and each of the plurality of pieces of narrow range three-dimensional measurement information, and creating synthetic three-dimensional information on the measurement range.

Abstract: An intraoral three-dimensional measuring method, comprising: acquiring, with a handy scanner, wide range three-dimensional measurement information on a three-dimensional shape measured on a wide range in a desirable measurement range in an intraoral space; acquiring, with the handy scanner, a plurality of pieces of narrow range three-dimensional measurement information each on a three-dimensional shape measured on a narrow range narrower than the wide range in the measurement range; and locating, with a controller, the plurality of pieces of narrow range three-dimensional measurement information based on the wide range three-dimensional measurement information by use of, as a synthesis reference, intra-measurement range position information common to the wide range three-dimensional measurement information and each of the plurality of pieces of narrow range three-dimensional measurement information, and creating synthetic three-dimensional information on the measurement range.

Abstract: An intraoral three-dimensional measuring method, comprising: acquiring, with a handy scanner, wide range three-dimensional measurement information on a three-dimensional shape measured on a wide range in a desirable measurement range in an intraoral space; acquiring, with the handy scanner, a plurality of pieces of narrow range three-dimensional measurement information each on a three-dimensional shape measured on a narrow range narrower than the wide range in the measurement range; and locating, with a controller, the plurality of pieces of narrow range three-dimensional measurement information based on the wide range three-dimensional measurement information by use of, as a synthesis reference, intra-measurement range position information common to the wide range three-dimensional measurement information and each of the plurality of pieces of narrow range three-dimensional measurement information, and creating synthetic three-dimensional information on the measurement range.

Abstract: A reprogramming gene-loaded Sendai viral vector comprising Sendai virus genes and reprogramming genes, wherein the Sendai virus genes include an NP gene, P/C gene, M gene, F gene, HN gene and L gene, wherein each of the M gene, the F gene and the FIN gene is from a Sendai virus strain Cl.151-derived gene and wherein at least one of the M gene, the F gene and the HN gene is functionally deleted and the L gene encodes the amino-acid sequence of the L protein in which the amino-acid residue at position 1618 is valine and a method of producing the same.

Abstract: The present invention relates to cephalosporin antibacterial compounds of Formula (I): or corresponding pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, compound preparation and treatment methods for bacterial infections, especially those caused by gram-negative bacteria.

Abstract: The present invention provides a novel compound which has a wide antimicrobial spectrum, and in particular exhibits potent antimicrobial activity against beta-lactamase producing Gram negative bacteria. Specifically, the present invention provides a compound of the formula (I): wherein each symbol is as defined in the specification, or an amino-protected compound when the amino group is present on the ring in the 7-side chain, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same.

Abstract: An OCT measuring mechanism for acquiring the optical coherence tomography information and a surface shape measuring mechanism for acquiring the three-dimensional shape information share a display device, a control device, a light source, a scanning mirror, a light transmission/receiving path and an entering/exiting opening. The scanning mirror, the light transmission/receiving path, the entering/exiting opening are included in a handpiece operable to make a diagnosis on a diagnostic target site.

Abstract: A compound represented by formula (I) or a pharmaceutically acceptable salt thereof wherein A represents a group represented by one of formulae (i)-(iii); B represents a group represented by formula (v) or (vi); and E represents a substituted or unsubstituted heterocyclic group having a cationic nitrogen atom.

Abstract: This invention provides Cephem compounds having the formula: or an ester, a protected compound at the amino on the ring in the 7-side chain, a pharmaceutically acceptable salt, or a solvate thereof, a pharmaceutical composition thereof, and a method for treating a bacterial infectious disease with the compound, the ester, the protected compound, the salt, or the solvate thereof, wherein the symbols in the formula are defined in the specification. The compounds exhibit potent antimicrobial spectrum against a variety of bacteria including Gram negative bacteria and/or Gram positive bacteria, preferably beta-lactamase producing Gram negative bacteria, more preferably, multi-drug resistant microbials, in particular, Class B type metallo-beta-lactamase producing Gram negative bacteria, and still preferably extended-spectrum beta-lactamase (ESBL) producing bacteria. The compounds most preferably do not exhibit cross-resistance against known Cephem drugs or Carbapenem drugs.

Abstract: A compound of the formula: wherein X is —N?, —CH?, or the like; W is —CH2— or the like; U is —S— or the like; R1 and R2 are each independently hydrogen, halogen, optionally substituted lower alkyl, or the like; Q is a single bond or the like; R3 is hydrogen or the like; Ring A is a 6-membered aromatic heterocyclic group having 1-3 nitrogen atoms; each R4 is independently hydrogen, halogen, or the like; m is an integer from 0 to 2; G is —C(?O)— or the like; D is a single bond, —NH—, or the like; and E is a cyclic quaternary ammonium group, or an ester, a protected compound at the amino on the ring in the 7-side chain, a pharmaceutically acceptable salt, or a solvate thereof.

Abstract: A compound represented by formula (I) or a pharmaceutically acceptable salt thereof wherein A represents a group represented by one of formulae (i)-(iii); B represents a group represented by formula (v) or (vi); and E represents a substituted or unsubstituted heterocyclic group having a cationic nitrogen atom.

Abstract: The present invention relates to cephalosporin antibacterial compounds of Formula (I): or corresponding pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, compound preparation and treatment methods for bacterial infections, especially those caused by gram-negative bacteria.

Abstract: The present invention provides a novel compound which has a wide antimicrobial spectrum, and in particular exhibits potent antimicrobial activity against beta-lactamase producing Gram negative bacteria. Specifically, the present invention provides a compound of the formula (I): wherein each symbol is as defined in the specification, or an amino-protected compound when the amino group is present on the ring in the 7-side chain, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same.

Abstract: An OCT measuring mechanism for acquiring the optical coherence tomography information and a surface shape measuring mechanism for acquiring the three-dimensional shape information share a display device, a control device, a light source, a scanning mirror, a light transmission/receiving path and an entering/exiting opening. The scanning mirror, the light transmission/receiving path, the entering/exiting opening are included in a handpiece operable to make a diagnosis on a diagnostic target site.