Abstract: The present disclosure provides a muffler system that can effectively reduce exhaust noises. The muffler system includes an exhaust passage and a first muffler. The exhaust passage is configured to allow a flow of an exhaust gas. The first muffler is an expansion chamber muffler and disposed in the exhaust passage. The first muffler is situated upstream of a first position in a flow direction of the exhaust gas. The first position is located away from an upstream end of the exhaust passage by one third of an entire length of the exhaust passage.

Abstract: A muffler comprises an outer shell, an outlet pipe, and a restraining mechanism. A restraining mechanism restrains a height of spout of a liquid that flows inside the outlet pipe through a designated vent hole, the designated vent hole is at least one vent hole facing against a bottom surface of the outer shell among the at least one vent hole that the outlet pipe comprises.

Abstract: A muffler comprises an outer shell, an outlet pipe, and a restraining mechanism. A restraining mechanism restrains a height of spout of a liquid that flows inside the outlet pipe through a designated vent hole, the designated vent hole is at least one vent hole facing against a bottom surface of the outer shell among the at least one vent hole that the outlet pipe comprises.

Abstract: A muffler comprises an outer shell, an outlet pipe, and a restraining mechanism. A restraining mechanism restrains a height of spout of a liquid that flows inside the outlet pipe through a designated vent hole, the designated vent hole is at least one vent hole facing against a bottom surface of the outer shell among the at least one vent hole that the outlet pipe comprises.

Abstract: An exhaust pipe connection structure for interconnecting a connection pipe and an exhaust pipe that are arranged in an exhaust system of an, internal combustion engine. Either of the connection pipe or the exhaust pipe is inserted into the other, and the portion where the connection pipe and the exhaust pipe overlap each other is radially deformed and swaged.

Abstract: First, the present inventors assessed the effect of the compound represented by formula (III) below on Huh-7 cells infected with HBV, and demonstrated that the compound alone had an anti-HBV effect in vitro. Formula (III) Then, the present inventors revealed that the HBV replication-suppressing effect of PEG-IFN is enhanced in chimeric mice having a human liver infected with genotype C or A HBV when PEG-IFN is used in combination with the compound represented by formula (III) above. The present inventors also revealed that the HBV replication-suppressing effect of Entecavir is enhanced in chimeric mice having a human liver infected with genotype C HBV (wild-type and Entecavir-resistant strains) when Entecavir is used in combination with the compound represented by formula (III) above.

Abstract: The object of the present invention is to provide a pharmaceutical composition for preventing or treating viral infectious diseases. The compounds of the present invention have extremely potent anti-HCV activity and HCV growth inhibitory effects, and since they also only demonstrate mild cytotoxicity in vivo, a pharmaceutical composition containing the compound of the present invention is extremely useful as an anti-HCV preventive/therapeutic agent.

Abstract: The object of the present invention is to provide a pharmaceutical composition for preventing or treating viral infectious diseases. The compounds of the present invention have extremely potent anti-HCV activity and HCV growth inhibitory effects, and since they also only demonstrate mild cytotoxicity in vivo, a pharmaceutical composition containing the compound of the present invention is extremely useful as an anti-HCV preventive/therapeutic agent.

Abstract: The object of the present invention is to provide a compound useful for the prevention and treatment of viral infectious diseases, and particularly liver diseases caused by HCV infection due to its having a high degree of replication inhibitory activity against HCV, its production method, an intermediate compound useful for its production and a pharmaceutical composition containing these compounds, and the present invention relates to a compound represented by the formula (I): (wherein A represents —(CH2)n—, etc.; B represents —(C?O)—, etc.; D represents —(CH2)m—R?, etc.; E represents a hydrogen atom, etc.; G represents —(CH2)p-J, etc.; bond Q represents a single bond or double bond; and R1, R2 and R3 may be the same or different and each represent a hydrogen atom, etc.), a prodrug thereof or a pharmaceutically acceptable salt thereof.

Abstract: The object of the present invention is to provide a pharmaceutical composition for preventing or treating viral infectious diseases. The compounds of the present invention have extremely potent anti-HCV activity and HCV growth inhibitory effects, and since they also only demonstrate mild cytotoxicity in vivo, a pharmaceutical composition containing the compound of the present invention is extremely useful as an anti-HCV preventive/therapeutic agent.

Abstract: The object of the present invention is to provide a compound useful for the prevention and treatment of viral infectious diseases, and particularly liver diseases caused by HCV infection due to its having a high degree of replication inhibitory activity against HCV, its production method, an intermediate compound useful for its production and a pharmaceutical composition containing these compounds, and the present invention relates to a compound represented by the formula (I): (wherein A represents —(CH2)n—, etc.; B represents —(C?O)—, etc.; D represents —(CH2)m—R?, etc.; E represents a hydrogen atom, etc.; G represents —(CH2)p-J, etc.; bond Q represents a single bond or double bond; and R1, R2 and R3 may be the same or different and each represent a hydrogen atom, etc.), a prodrug thereof or a pharmaceutically acceptable salt thereof.

Abstract: A system for compensating for mislanding of electron beams on the screen of a color cathode ray tube as a result of thermal expansion of a beam selecting structure in the tube comprises electromagnetic devices provided on the tube for producing respective magnetic fields by means of a current supplied thereto so as to change the paths of the electron beams passing through the beam selecting structure, and a circuit for supplying to the electromagnetic devices a current varying in response to a difference between the temperature of the beam selecting structure and the ambient temperature about the tube.