Abstract: An expanded molded article comprising a fused body of expanded particles including a non-crosslinked olefin-based elastomer and not including a mineral oil, the expanded molded article having a density of 0.015 to 0.5 g/cm3 and a compression set of 25% or less.

Abstract: Amide-based elastomer expanded particles comprising, as a base resin, a non-crosslinked amide-based elastomer having a Shore D hardness of 65 or less, and having an average cell diameter of 20 to 250 ?m.

Abstract: An object of the present invention is to create a novel engineered Protein A ligand having better antibody dissociation properties in the presence of an acid than conventional engineered Protein A ligands and a further object of the present invention is to create a novel engineered Protein A ligand having higher alkali resistance. The present invention is to provide a protein having an affinity for an immunoglobulin, including an amino acid sequence derived from any of E, D, A, B and C domains of Protein A, wherein at least one Gly residue in the amino acid sequence is replaced with an amino acid other than Ala, and the protein has a lower affinity for an Fab region of an immunoglobulin than a protein including an amino acid sequence in which the Gly residue is replaced with Ala. Also, the present invention is to provide the protein having an affinity for an immunoglobulin, which has improved chemical stability in an alkaline condition compared to the corresponding domain.

Abstract: A handheld blower has a body including a combustion engine and a blower section driven by the combustion engine, and a handle coupled to the body. The blower section has an air outlet directed forward with respect to an operator. The handle has a grip portion extending in a front-back direction with respect to the operator, a front arm extending from a front portion of the grip portion to the body, and a rear arm extending from a rear portion of the grip portion to the body. The front arm and the rear arm are more flexible in the front-back direction than in directions perpendicular to the front-back direction.

Abstract: An object of the present invention is to create a novel engineered Protein A ligand having better antibody dissociation properties in the acidic condition compared with known engineered Protein A ligands. The present invention provides a protein having an affinity for an immunoglobulin, including an amino acid sequence obtained by introducing, into an amino acid sequence derived from any of E, D, A, B and C domains of Protein A, at least one amino acid substitution at any one or more of amino acid residues corresponding to positions 31 to 37 of the A, B and C domains (positions 29 to 35 of the E domain, positions 34 to 40 of the D domain), which are conserved in all the domains, the protein having a lower affinity for an Fab region of an immunoglobulin than a protein having the amino acid sequence before introduction of the substitution.

Abstract: A handheld blower has a body including a combustion engine and a blower section driven by the combustion engine, and a handle coupled to the body. The blower section has an air outlet directed forward with respect to an operator. The handle has a grip portion extending in a front-back direction with respect to the operator, a front arm extending from a front portion of the grip portion to the body, and a rear arm extending from a rear portion of the grip portion to the body. The front arm and the rear arm are more flexible in the front-back direction than in directions perpendicular to the front-back direction.

Abstract: An object of the present invention is to create a novel engineered Protein A ligand having better antibody dissociation properties in the presence of an acid than conventional engineered Protein A ligands and a further object of the present invention is to create a novel engineered Protein A ligand having higher alkali resistance. The present invention is to provide a protein having an affinity for an immunoglobulin, including an amino acid sequence derived from any of E, D, A, B and C domains of Protein A, wherein at least one Gly residue in the amino acid sequence is replaced with an amino acid other than Ala, and the protein has a lower affinity for an Fab region of an immunoglobulin than a protein including an amino acid sequence in which the Gly residue is replaced with Ala. Also, the present invention is to provide the protein having an affinity for an immunoglobulin, which has improved chemical stability in an alkaline condition compared to the corresponding domain.

Abstract: To provide a work machine in which traveling devices and an implement device can be operated by common operating levers, wherein switching operation is easy and a changeover is easily confirmed. Inside a cab of the work machine, there are provided travel pedals, with which the traveling devices can be operated, and operating levers, with which the traveling devices and the implement device can be operated. A changeover switch is provided on a console positioned in the vicinity of one side of an operating sheet. The changeover switch switches over between a traveling mode, in which traveling operation is possible by the operating levers, and a work mode, in which implement operation is possible by the operating levers.

Abstract: In a work machine equipped with a switchover means enabling selective operation of traveling devices and a work device by means of common operating levers, switchover can easily be performed and also easily recognized. In a work machine having traveling devices and a work device, operating levers that are capable of operating the traveling devices and the work device are respectively disposed at the sides of an operating seat. A foot switch connected to a controller is disposed in the proximity of and operable with a foot of an operator seated at the operating seat. While the foot switch is being operated with the foot, the traveling devices are operated by the operating levers through the controller. While the foot switch is not being operated, the work device is operated by means of the operating levers through the controller.

Abstract: A hand operation portion of an endoscope is held by an endoscope holder of a holding device, and an insertion auxiliary member is held by an auxiliary member holder. The endoscope holder and the auxiliary member holder are slidably supported along a guide rail on a stage, and linearly moved toward a mouth of a patient.

Abstract: An endoscope apparatus, comprising: an endoscope with a balloon attached to a tip end part of an insertion section, and an insertion assisting tool into which the insertion section of the endoscope is inserted and which assists the insertion section in being inserted into a body cavity, wherein a tip end part of the insertion assisting tool is constructed to have a diameter enlarging structure capable of being enlarged in diameter, and by enlarging a diameter of the tip end part, a balloon of the insertion section protruded from a tip end of the insertion assisting tool is made extractable from the insertion assisting tool.

Abstract: To provide a work machine in which traveling devices and an implement device can be operated by common operating levers, wherein switching operation is easy and a changeover is easily confirmed. Inside a cab of the work machine, there are provided travel pedals, with which the traveling devices can be operated, and operating levers, with which the traveling devices and the implement device can be operated. A changeover switch is provided on a console positioned in the vicinity of one side of an operating sheet. The changeover switch switches over between a traveling mode, in which traveling operation is possible by the operating levers, and a work mode, in which implement operation is possible by the operating levers.

Abstract: A backpack blower comprising a blower which has an air intake opening, a backpack frame which is used to support the blower on the back of a user, and a back pad that is coupled to the backpack frame and contacts the back of the user. The back pad is composed of a cushion material and has a back surface contacting the back of the user and an opposite surface. The air intake opening communicates with at least a portion of the opposite surface, so that the air intake noise of the blower can reach at least the portion of the opposite surface.

Abstract: The subject of the present invention is to provide a ?-lactam acylase protein having high activity, a gene coding for said ?-lactam acylase protein, a recombinant vector having said gene, a transformant containing said recombinant vector, and a method of producing a ?-lactam antibiotic such as amoxycillin using said ?-lactam acylase. A ?-lactam acylase gene of Stenotrophomonas maltophilia was cloned, the DNA base sequence and the amino acid sequence expected therefrom was determined, and a Stenotrophomonas ?-lactam acylase gene was obtained. This gene was found to code for a protein with a molecular weight of about 70 kDa and having ?-lactam acylase activity, and could efficiently produce amoxycillin without being inhibited by phenylacetic acid, etc. Furthermore, by modification of the amino acid sequence, a protein which can more efficiently produce amoxycillin could be obtained.

Abstract: The subject of the present invention is to provide a ?-lactam acylase protein having high activity, a gene coding for said ?-lactam acylase protein, a recombinant vector having said gene, a transformant containing said recombinant vector, and a method of producing a ?-lactam antibiotic such as amoxycillin using said ?-lactam acylase. A ?-lactam acylase gene of Stenotrophomonas maltophilia was cloned, the DNA base sequence and the amino acid sequence expected therefrom was determined, and a Stenotrophomonas ?-lactam acylase gene was obtained. This gene was found to code for a protein with a molecular weight of about 70 kDa and having ?-lactam acylase activity, and could efficiently produce amoxycillin without being inhibited by phenylacetic acid, etc. Furthermore, by modification of the amino acid sequence, a protein which can more efficiently produce amoxycillin could be obtained.

Abstract: An endoscope apparatus comprising an endoscope and an insertion aid through whose base end of an insert part of the endoscope is inserted, wherein the outer circumferential face of the insert part of the endoscope and/or the inner circumferential face of the insertion aid is coated with a lubricating coat material, and the lubricating coat material is formed thicker in the tip portion of the outer circumferential face of the insert part of the endoscope and/or the inner circumferential face of the insertion aid than in the base end portion of the same.

Abstract: A hand operation portion of an endoscope is held by an endoscope holder of a holding device, and an insertion auxiliary member is held by an auxiliary member holder. The endoscope holder and the auxiliary member holder are slidably supported along a guide rail on a stage, and linearly moved toward a mouth of a patient.

Abstract: An endoscope apparatus, comprising: an endoscope with a balloon attached to a tip end part of an insertion section, and an insertion assisting tool into which the insertion section of the endoscope is inserted and which assists the insertion section in being inserted into a body cavity, wherein a tip end part of the insertion assisting tool is constructed to have a diameter enlarging structure capable of being enlarged in diameter, and by enlarging a diameter of the tip end part, a balloon of the insertion section protruded from a tip end of the insertion assisting tool is made extractable from the insertion assisting tool.

Abstract: A first balloon is fitted to an insertion section of an endoscope, and the insertion section is fixed to an intestinal canal by inflating the first balloon. The insertion assisting tool covers the insertion section, and is pushed to a tip end portion side along the insertion section. When the insertion assisting tool is pushed to the limit state, an indicator provided at a surface of the insertion section appears, and the limit state can be recognized.