Abstract: New agents of carbacyclin derivatives are disclosed, which are represented by the following formula: ##STR1## wherein A is a --CH.dbd.CH-- or --C.tbd.C-- group. B is a substituted or unsubstituted indanyl group, substituted or unsubstituted benzodioxanyl group, substituted or unsubstituted benzodioxolanyl group or 2,3,5,6,7, 8-hexahydrobenzodioxanyl group. D is --CH.sub.2 -- or --O--. .about.OH group represents .alpha. or .beta. configuration of OH group; and ##STR2## These compounds are useful as anit-ulcer, anti-hypertensive or anti-thrombotic agents.

Abstract: A wire spring-manufacturing apparatus which comprises a wire feeder; a device for clamping a straight wire of prescribed length delivered from the wire feeder substantially at the center and intermittently rotating said wire about its axis; and a pair of wire-bending devices so disposed as to intermittently approach each other toward the wire-rotating device relative to the rotation of said wire, thereby successively bending both end portions of said wire to form spring legs.