Patents by Inventor Masomeh B. Sticklen

Masomeh B. Sticklen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8350123
    Abstract: The present invention provides transgenic cover crop plants which after harvest degrade the hemicellulose and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise cellulase, hemicellulase and optionally ligninase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular, the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the hemicellulase and cellulase which then degrade the hemicellulose and cellulose of the transgenic plants to produce the fermentable sugars.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: January 8, 2013
    Assignee: Board of Trustees of Michigan State University
    Inventor: Masomeh B. Sticklen
  • Publication number: 20120090231
    Abstract: The present invention provides transgenic cover crop plants which after harvest degrade the hemicellulose and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise cellulase, hemicellulase and optionally ligninase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular, the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the hemicellulase and cellulase which then degrade the hemicellulose and cellulose of the transgenic plants to produce the fermentable sugars.
    Type: Application
    Filed: October 19, 2011
    Publication date: April 19, 2012
    Applicant: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
    Inventor: Masomeh B. Sticklen
  • Patent number: 8093456
    Abstract: The present invention provides transgenic cover crop plants which after harvest degrade the hemicellulose and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise cellulase, hemicellulase and optionally ligninase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular, the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the hemicellulase and cellulase which then degrade the hemicellulose and cellulose of the transgenic plants to produce the fermentable sugars.
    Type: Grant
    Filed: December 4, 2007
    Date of Patent: January 10, 2012
    Assignee: Board of Trustees of Michigan State University
    Inventor: Masomeh B. Sticklen
  • Patent number: 7696411
    Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.
    Type: Grant
    Filed: November 20, 2007
    Date of Patent: April 13, 2010
    Assignee: Board of Trustees of Michigan State University
    Inventors: Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Maqbool
  • Publication number: 20090203079
    Abstract: Plant proteins isolated from monocot plants from transformation of the monocot plant with DNA at least 80% homologous to the bglA gene encoding ?-glucosidase from a rumen bacterium which is Butyrivibrio fibrisolvens H17c and targeted to a subcellular compartment. The transformed plant is ground after the ?-glucosidase has been accumulated, and the protein is extracted or used directly with the ground plant material to degrade cellobiose, in particular, to produce sugars used in fermentations, particularly to produce ethanol. Also, a gene at least 80% homologous to DNA XYL1 gene encoding a xylanase is also provided in a transformed plant and used to produce sugars.
    Type: Application
    Filed: March 30, 2009
    Publication date: August 13, 2009
    Applicant: Board of Trustees of Michigan State University
    Inventors: Masomeh B. Sticklen, Callista B. Ransom
  • Patent number: 7569745
    Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: August 4, 2009
    Assignee: Board of Trustees of Michigan State University
    Inventors: Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Maqbool
  • Publication number: 20080235830
    Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.
    Type: Application
    Filed: May 5, 2008
    Publication date: September 25, 2008
    Applicant: Board of Trustees of Michigan State University
    Inventors: Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Maqbool
  • Publication number: 20080235820
    Abstract: A transgenic maize plant and methods of using the transgenic maize plant having at least a portion of a coding region of one or more lignin biosynthesis pathway enzymes. In one embodiment, the transgenic plant expresses short interfering RNA (siRNA) for the one or more lignin biosynthesis pathway enzymes that forms a double-strand to activate RNA interference (RNAi). The RNAi decreases expression of the one or more lignin biosynthesis pathway enzymes in the transgenic plant. In a second embodiment, the transgenic plant has a cDNA for the one or more lignin biosynthesis pathway enzymes to increase expression of the one or more lignin biosynthesis pathway enzymes in the transgenic plant.
    Type: Application
    Filed: March 21, 2008
    Publication date: September 25, 2008
    Applicant: Board of Trustees of Michigan State University
    Inventor: Masomeh B. Sticklen
  • Patent number: 7423195
    Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.
    Type: Grant
    Filed: February 14, 2006
    Date of Patent: September 9, 2008
    Assignee: Board of Trustees of Michigan State University
    Inventors: Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Magbool
  • Publication number: 20080213871
    Abstract: The present invention relates to compositions and methods for providing RNA Interference (RNAi) vectors comprising maize lignin biosynthesis enzymes for altering lignin content of plants. Specifically, plants comprising RNAi maize lignin vectors for reducing or altering lignin content are provided for reducing pretreatment costs of biofuel production. Additionally, RNAi maize lignin vectors are provided for altering cellulose production in plants for reducing pretreatment costs of plant biomass processing by increasing amounts of fermentable sugars.
    Type: Application
    Filed: November 29, 2007
    Publication date: September 4, 2008
    Inventor: Masomeh B. Sticklen
  • Patent number: 7371926
    Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.
    Type: Grant
    Filed: April 6, 2006
    Date of Patent: May 13, 2008
    Assignee: Board of Trustees of Michigan State University
    Inventors: Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Maqbool
  • Patent number: 7049485
    Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.
    Type: Grant
    Filed: October 18, 2001
    Date of Patent: May 23, 2006
    Assignee: Board of Trustees of Michigan State University
    Inventors: Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Maqbool
  • Publication number: 20020138878
    Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.
    Type: Application
    Filed: October 18, 2001
    Publication date: September 26, 2002
    Applicant: Board of Trustees of Michigan State University
    Inventors: Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Maqbool
  • Patent number: 6100456
    Abstract: Lepidopteran insect resistant transformed potato plants are described. In particular, the transformation of potato plants with five to ten copies of a translational fusion encoding the 68 kD lepidopteran-specific toxin from Bacillus thuringiensis var. kurstaki HD-73 and neomycin phosphotransferase II is described. The transgenic potato plants were resistant to the tobacco hornworm, a lepidopteran insect which is susceptible to Bacillus thuringiensis var. kurstaki toxin.
    Type: Grant
    Filed: March 16, 1992
    Date of Patent: August 8, 2000
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Masomeh B. Sticklen, Jianping Cheng
  • Patent number: 5767368
    Abstract: A method for isolating a cereal plant with foreign DNA by bombarding meristem primordia tissue with particles coated with the foreign DNA in a culture media is described. The foreign DNA in the transformed plants can provide proteins which impart disease and/or insect resistance or other desirable properties.
    Type: Grant
    Filed: April 3, 1995
    Date of Patent: June 16, 1998
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Heng Zhong, Masomeh B. Sticklen
  • Patent number: 5728382
    Abstract: cDNA as set forth in SEQ ID NO:1 encoding a chitinase, a signal peptide and a vacuole sorting peptide. The chitinase is antifungal and can be used to treat plants, particularly American elms infected with a fungus which kills the trees. The cDNA can be used to produce recombinant cells which produce the chitinase or which impart resistance to the fungi.
    Type: Grant
    Filed: February 22, 1996
    Date of Patent: March 17, 1998
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Masomeh B. Sticklen, Ravindra K. Hajela
  • Patent number: 5539095
    Abstract: cDNA as set forth in SEQ ID NO:1 encoding a chitinase, a signal peptide and a vacuole sorting peptide. The chitinase is antifungal and can be used to treat plants, particularly American elms infected with a fungus which kills the trees. The cDNA can be used to produce recombinant cells which produce the chitinase or which impart resistance to the fungi.
    Type: Grant
    Filed: August 4, 1994
    Date of Patent: July 23, 1996
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Masomeh B. Sticklen, Ravindra K. Hajela
  • Patent number: 5320961
    Abstract: A method for asexual in vitro propagation of corn plants is described. The plant tissue (shoot tips or apices) are differentiated with 2,4-dichlorophenoxy acetic acid (2,4-D) and N.sup.6 -benzyladenine (BA) and mixtures thereof and then the differentiated tissue is grown in indole-3-butyric acid (IBA) to produce the corn plant which is fertile.
    Type: Grant
    Filed: November 16, 1992
    Date of Patent: June 14, 1994
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Heng Zhong, Masomeh B. Sticklen, Chinnathambi Srinivasan
  • Patent number: 5281529
    Abstract: A method for in vitro sexual reproduction in corn plants is described. The method involves differentiation of shoot tips with N.sup.6 -benzyladenine (BA) into ears and then ovaries and pollinating the ovaries to produce kernels. The kernels are then germinated to produce the plant. The method is particularly useful for maintaining lives of corn and for genetic manipulation by using different pollens.
    Type: Grant
    Filed: November 16, 1992
    Date of Patent: January 25, 1994
    Assignee: Board of Trustees operating Michigan State University
    Inventors: Heng Zhong, Masomeh B. Sticklen