Patents by Inventor Masomeh B. Sticklen
Masomeh B. Sticklen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8350123Abstract: The present invention provides transgenic cover crop plants which after harvest degrade the hemicellulose and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise cellulase, hemicellulase and optionally ligninase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular, the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the hemicellulase and cellulase which then degrade the hemicellulose and cellulose of the transgenic plants to produce the fermentable sugars.Type: GrantFiled: October 19, 2011Date of Patent: January 8, 2013Assignee: Board of Trustees of Michigan State UniversityInventor: Masomeh B. Sticklen
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Publication number: 20120090231Abstract: The present invention provides transgenic cover crop plants which after harvest degrade the hemicellulose and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise cellulase, hemicellulase and optionally ligninase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular, the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the hemicellulase and cellulase which then degrade the hemicellulose and cellulose of the transgenic plants to produce the fermentable sugars.Type: ApplicationFiled: October 19, 2011Publication date: April 19, 2012Applicant: BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITYInventor: Masomeh B. Sticklen
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Patent number: 8093456Abstract: The present invention provides transgenic cover crop plants which after harvest degrade the hemicellulose and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise cellulase, hemicellulase and optionally ligninase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular, the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the hemicellulase and cellulase which then degrade the hemicellulose and cellulose of the transgenic plants to produce the fermentable sugars.Type: GrantFiled: December 4, 2007Date of Patent: January 10, 2012Assignee: Board of Trustees of Michigan State UniversityInventor: Masomeh B. Sticklen
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Patent number: 7696411Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.Type: GrantFiled: November 20, 2007Date of Patent: April 13, 2010Assignee: Board of Trustees of Michigan State UniversityInventors: Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Maqbool
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Publication number: 20090203079Abstract: Plant proteins isolated from monocot plants from transformation of the monocot plant with DNA at least 80% homologous to the bglA gene encoding ?-glucosidase from a rumen bacterium which is Butyrivibrio fibrisolvens H17c and targeted to a subcellular compartment. The transformed plant is ground after the ?-glucosidase has been accumulated, and the protein is extracted or used directly with the ground plant material to degrade cellobiose, in particular, to produce sugars used in fermentations, particularly to produce ethanol. Also, a gene at least 80% homologous to DNA XYL1 gene encoding a xylanase is also provided in a transformed plant and used to produce sugars.Type: ApplicationFiled: March 30, 2009Publication date: August 13, 2009Applicant: Board of Trustees of Michigan State UniversityInventors: Masomeh B. Sticklen, Callista B. Ransom
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Patent number: 7569745Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.Type: GrantFiled: May 5, 2008Date of Patent: August 4, 2009Assignee: Board of Trustees of Michigan State UniversityInventors: Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Maqbool
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Publication number: 20080235830Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.Type: ApplicationFiled: May 5, 2008Publication date: September 25, 2008Applicant: Board of Trustees of Michigan State UniversityInventors: Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Maqbool
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Publication number: 20080235820Abstract: A transgenic maize plant and methods of using the transgenic maize plant having at least a portion of a coding region of one or more lignin biosynthesis pathway enzymes. In one embodiment, the transgenic plant expresses short interfering RNA (siRNA) for the one or more lignin biosynthesis pathway enzymes that forms a double-strand to activate RNA interference (RNAi). The RNAi decreases expression of the one or more lignin biosynthesis pathway enzymes in the transgenic plant. In a second embodiment, the transgenic plant has a cDNA for the one or more lignin biosynthesis pathway enzymes to increase expression of the one or more lignin biosynthesis pathway enzymes in the transgenic plant.Type: ApplicationFiled: March 21, 2008Publication date: September 25, 2008Applicant: Board of Trustees of Michigan State UniversityInventor: Masomeh B. Sticklen
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Patent number: 7423195Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.Type: GrantFiled: February 14, 2006Date of Patent: September 9, 2008Assignee: Board of Trustees of Michigan State UniversityInventors: Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Magbool
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Publication number: 20080213871Abstract: The present invention relates to compositions and methods for providing RNA Interference (RNAi) vectors comprising maize lignin biosynthesis enzymes for altering lignin content of plants. Specifically, plants comprising RNAi maize lignin vectors for reducing or altering lignin content are provided for reducing pretreatment costs of biofuel production. Additionally, RNAi maize lignin vectors are provided for altering cellulose production in plants for reducing pretreatment costs of plant biomass processing by increasing amounts of fermentable sugars.Type: ApplicationFiled: November 29, 2007Publication date: September 4, 2008Inventor: Masomeh B. Sticklen
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Patent number: 7371926Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.Type: GrantFiled: April 6, 2006Date of Patent: May 13, 2008Assignee: Board of Trustees of Michigan State UniversityInventors: Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Maqbool
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Patent number: 7049485Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.Type: GrantFiled: October 18, 2001Date of Patent: May 23, 2006Assignee: Board of Trustees of Michigan State UniversityInventors: Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Maqbool
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Publication number: 20020138878Abstract: The present invention provides transgenic plants which after harvest degrade the lignin and cellulose therein to fermentable sugars which can further be fermented to ethanol or other products. In particular, the transgenic plants comprise ligninase and cellulase genes from microbes operably linked to a DNA encoding a signal peptide which targets the fusion polypeptide produced therefrom to an organelle of the plant, in particular the chloroplasts. When the transgenic plants are harvested, the plants are ground to release the ligninase and cellulase which then degrade the lignin and cellulose of the transgenic plants to produce the fermentable sugars.Type: ApplicationFiled: October 18, 2001Publication date: September 26, 2002Applicant: Board of Trustees of Michigan State UniversityInventors: Masomeh B. Sticklen, Bruce E. Dale, Shahina B. Maqbool
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Patent number: 6100456Abstract: Lepidopteran insect resistant transformed potato plants are described. In particular, the transformation of potato plants with five to ten copies of a translational fusion encoding the 68 kD lepidopteran-specific toxin from Bacillus thuringiensis var. kurstaki HD-73 and neomycin phosphotransferase II is described. The transgenic potato plants were resistant to the tobacco hornworm, a lepidopteran insect which is susceptible to Bacillus thuringiensis var. kurstaki toxin.Type: GrantFiled: March 16, 1992Date of Patent: August 8, 2000Assignee: Board of Trustees operating Michigan State UniversityInventors: Masomeh B. Sticklen, Jianping Cheng
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Patent number: 5767368Abstract: A method for isolating a cereal plant with foreign DNA by bombarding meristem primordia tissue with particles coated with the foreign DNA in a culture media is described. The foreign DNA in the transformed plants can provide proteins which impart disease and/or insect resistance or other desirable properties.Type: GrantFiled: April 3, 1995Date of Patent: June 16, 1998Assignee: Board of Trustees operating Michigan State UniversityInventors: Heng Zhong, Masomeh B. Sticklen
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Patent number: 5728382Abstract: cDNA as set forth in SEQ ID NO:1 encoding a chitinase, a signal peptide and a vacuole sorting peptide. The chitinase is antifungal and can be used to treat plants, particularly American elms infected with a fungus which kills the trees. The cDNA can be used to produce recombinant cells which produce the chitinase or which impart resistance to the fungi.Type: GrantFiled: February 22, 1996Date of Patent: March 17, 1998Assignee: Board of Trustees operating Michigan State UniversityInventors: Masomeh B. Sticklen, Ravindra K. Hajela
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Patent number: 5539095Abstract: cDNA as set forth in SEQ ID NO:1 encoding a chitinase, a signal peptide and a vacuole sorting peptide. The chitinase is antifungal and can be used to treat plants, particularly American elms infected with a fungus which kills the trees. The cDNA can be used to produce recombinant cells which produce the chitinase or which impart resistance to the fungi.Type: GrantFiled: August 4, 1994Date of Patent: July 23, 1996Assignee: Board of Trustees operating Michigan State UniversityInventors: Masomeh B. Sticklen, Ravindra K. Hajela
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Patent number: 5320961Abstract: A method for asexual in vitro propagation of corn plants is described. The plant tissue (shoot tips or apices) are differentiated with 2,4-dichlorophenoxy acetic acid (2,4-D) and N.sup.6 -benzyladenine (BA) and mixtures thereof and then the differentiated tissue is grown in indole-3-butyric acid (IBA) to produce the corn plant which is fertile.Type: GrantFiled: November 16, 1992Date of Patent: June 14, 1994Assignee: Board of Trustees operating Michigan State UniversityInventors: Heng Zhong, Masomeh B. Sticklen, Chinnathambi Srinivasan
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Patent number: 5281529Abstract: A method for in vitro sexual reproduction in corn plants is described. The method involves differentiation of shoot tips with N.sup.6 -benzyladenine (BA) into ears and then ovaries and pollinating the ovaries to produce kernels. The kernels are then germinated to produce the plant. The method is particularly useful for maintaining lives of corn and for genetic manipulation by using different pollens.Type: GrantFiled: November 16, 1992Date of Patent: January 25, 1994Assignee: Board of Trustees operating Michigan State UniversityInventors: Heng Zhong, Masomeh B. Sticklen