Patents by Inventor Masoud Toloue

Masoud Toloue has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for improving removal of ribosomal RNA from biological samples
    Patent number: 11401543
    Abstract: The invention generally relates to compositions for maximizing capture of affinity-labeled molecules on solid supports. The disclosed methods and compositions were developed to maximize depletion of ribosomal RNA from total RNA samples, which is useful to improve the quality of RNA preparations used for applications such as massively parallel sequencing. The RNA depletion method is based on using long affinity-labeled RNA molecules that are complementary to all or part of the target ribosomal RNAs, as subtractive hybridization probes.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: August 2, 2022
    Assignee: BIOO Scientific Corporation
    Inventors: Marianna Goldrick, Lance Lepovitz, Masoud Toloue
  • METHODS AND KITS FOR REDUCING ADAPTER-DIMER FORMATION
    Publication number: 20200190565
    Abstract: The current teachings relate to methods for reducing adapter-dimer formation, particularly when preparing nucleic acids of interest for subsequent amplification and/or sequencing. Also described are kits for use in performing certain disclosed methods.
    Type: Application
    Filed: February 13, 2020
    Publication date: June 18, 2020
    Inventors: Masoud Toloue, Adam R. Morris, Kevin D. Allen
  • Methods and kits for reducing adapter-dimer formation
    Patent number: 10597706
    Abstract: The current teachings relate to methods for reducing adapter-dimer formation, particularly when preparing nucleic acids of interest for subsequent amplification and/or sequencing. Also described are kits for use in performing certain disclosed methods.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: March 24, 2020
    Assignee: BIOO Scientific Corporation
    Inventors: Masoud Toloue, Adam R. Morris, Kevin D. Allen
  • Methods and Compositions for Improving Removal of Ribosomal RNA from Biological Samples
    Publication number: 20190330682
    Abstract: The invention generally relates to compositions for maximizing capture of affinity-labeled molecules on solid supports. The disclosed methods and compositions were developed to maximize depletion of ribosomal RNA from total RNA samples, which is useful to improve the quality of RNA preparations used for applications such as massively parallel sequencing. The RNA depletion method is based on using long affinity-labeled RNA molecules that are complementary to all or part of the target ribosomal RNAs, as subtractive hybridization probes.
    Type: Application
    Filed: June 13, 2019
    Publication date: October 31, 2019
    Inventors: Marianna Goldrick, Lance Lepovitz, Masoud Toloue
  • Methods and compositions for improving removal of ribosomal RNA from biological samples
    Patent number: 10364455
    Abstract: The invention generally relates to compositions for maximizing capture of affinity-labeled molecules on solid supports. The disclosed methods and compositions were developed to maximize depletion of ribosomal RNA from total RNA samples, which is useful to improve the quality of RNA preparations used for applications such as massively parallel sequencing. The RNA depletion method is based on using long affinity-labeled RNA molecules that are complementary to all or part of the target ribosomal RNAs, as subtractive hybridization probes.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: July 30, 2019
    Assignee: BIOO Scientific Corporation
    Inventors: Marianna Goldrick, Lance Lepovitz, Masoud Toloue
  • METHODS AND KITS FOR REDUCING ADAPTER-DIMER FORMATION
    Publication number: 20170137875
    Abstract: The current teachings relate to methods for reducing adapter-dimer formation, particularly when preparing nucleic acids of interest for subsequent amplification and/or sequencing. Also described are kits for use in performing certain disclosed methods.
    Type: Application
    Filed: November 17, 2016
    Publication date: May 18, 2017
    Inventors: MASOUD TOLOUE, ADAM R. MORRIS, KEVIN D. ALLEN
  • METHODS AND KITS FOR NUCLEIC ACID ISOLATION
    Publication number: 20170121705
    Abstract: The current teachings disclose methods and kits for increasing the amount of nucleic acid that can be recovered from magnetic beads using elution solutions with high ionic strength.
    Type: Application
    Filed: November 3, 2016
    Publication date: May 4, 2017
    Inventors: MARIANNA GOLDRICK, Masoud TOLOUE
  • METHODS AND COMPOSITIONS FOR IMPROVING REMOVAL OF RIBOSOMAL RNA FROM BIOLOGICAL SAMPLES
    Publication number: 20140295418
    Abstract: The invention generally relates to compositions for maximizing capture of affinity-labeled molecules on solid supports. The disclosed methods and compositions were developed to maximize depletion of ribosomal RNA from total RNA samples, which is useful to improve the quality of RNA preparations used for applications such as massively parallel sequencing. The RNA depletion method is based on using long affinity-labeled RNA molecules that are complementary to all or part of the target ribosomal RNAs, as subtractive hybridization probes.
    Type: Application
    Filed: September 27, 2013
    Publication date: October 2, 2014
    Applicant: BIOO SCIENTIFIC CORPORATION
    Inventors: Marianna Goldrick, Lance Lepovitz, Masoud Toloue
  • RAPID AND EFFICIENT ASSAY TO ASSESS THE SEQUENCE AND SIZE OF 3' ENDS OF POLYNUCLEOTIDES
    Publication number: 20110269137
    Abstract: Described herein is an efficient, highly reproducible approach to assess poly(A) tail length on a mRNA specific basis. The embodiments herein have led to the development of a versatile, easy to use kit for biomedical researchers to address the impact of changes in poly(A) tail length in the post-transcriptional regulation of gene expression.
    Type: Application
    Filed: April 18, 2011
    Publication date: November 3, 2011
    Inventors: Lance P. Ford, Masoud Toloue, Marianna Goldrick, Jeffrey Wilusz