Patents by Inventor Massimiliano Arrighi

Massimiliano Arrighi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing rifaximin ?
    Patent number: 9708343
    Abstract: The present invention relates to a process for obtaining rifaximin ? comprising the following steps: a) reacting rifamycin O with 2-amino-4-picoline in the presence of a solvent mixture comprising water and a solvent selected from methyl isobutylketone, ethylacetate and a water soluble solvent; b) obtaining a rifaximin solution by removing the aqueous phase; c) obtaining rifaximin ? from the rifaximin solution, wherein when the solvent is a water soluble solvent, either methyl isobutylketone or ethylacetate is further added in step a). In another aspect the process of the invention relates to a process for obtaining the crystalline form ? of rifaximin comprising the following steps: i) contacting rifaximin or a rifaximin solution with exclusively ethylacetate, ii) obtaining the rifaximin in crystalline form ? by removing ethylacetate.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: July 18, 2017
    Assignee: Clarochem Ireland Ltd.
    Inventors: Enrico Vigano′, Renato Molteni, Simona Lanfranconi, Massimiliano Arrighi, Fabio Gatti
  • Polymorph of rifaximin and process for the preparation thereof
    Patent number: 8877770
    Abstract: The present invention relates to a new polymorph of Rifaximin, designated ?, and to a process for the preparation thereof. Under certain aspects, the invention also relates to pharmaceutical compositions comprising an effective amount of the polymorphic form ? of Rifaximin and a pharmaceutically acceptable carrier and its uses in the treatment of gastrointestinal conditions.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: November 4, 2014
    Assignee: Clarochem Ireland Limited
    Inventors: Enrico Vigano', Renato Molteni, Simona Lanfranconi, Massimiliano Arrighi, Fabio Gatti
  • POLYMORPH OF RIFAXIMIN AND PROCESS FOR THE PREPARATION THEREOF
    Publication number: 20140107144
    Abstract: The present invention relates to a new polymorph of Rifaximin, designated ?, and to a process for the preparation thereof. Under certain aspects, the invention also relates to pharmaceutical compositions comprising an effective amount of the polymorphic form ? of Rifaximin and a pharmaceutically acceptable carrier and its uses in the treatment of gastrointestinal conditions.
    Type: Application
    Filed: May 18, 2012
    Publication date: April 17, 2014
    Applicant: CLAROCHEM IRELAND LIMITED
    Inventors: Enrico Vigano, Renato Molteni, Simona Lanfranconi, Massimiliano Arrighi, Fabio Gatti