Patents by Inventor Massimo ALBERTI

Massimo ALBERTI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Integrated microfluidic system for culturing and testing
    Patent number: 11566212
    Abstract: The present disclosure describes a microfluidic chip for culturing and in vitro testing of 3D organotypic cultures. The tests may be performed directly on the organotypic culture in the microfluidic chip. The microfluidic chip includes at least one microfluidic unit which includes two fluidic compartments, such as upper and lower, separated by a permeable supporting structure, one or more access opening for the fluidic compartments, and a set of lids interchangeable with a set of insets. The permeable support structure serves as a support for the organotypic culture. The upper and lower compartments may include inlets and outlets which allow fluids to be perfused into the lower compartment and fluids to be perfused into the upper compartment. The access opening may be closed with a lid or accommodate an inset.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: January 31, 2023
    Assignee: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Paul Bigliardi, Zhiping Wang, Ruige Wu, Massimo Alberti, Bo Wu, Mei Bigliardi-Qi, Sriram Gopu, Srinivas Ramasamy, Yuri Hebert Dancik
  • INTEGRATED MICROFLUIDIC SYSTEM FOR CULTURING AND TESTING
    Publication number: 20190177678
    Abstract: The present disclosure describes a microfluidic chip for culturing and in vitro testing of 3D organotypic cultures. The tests may be performed directly on the organotypic culture in the microfluidic chip. The microfluidic chip includes at least one microfluidic unit which includes two fluidic compartments, such as upper and lower, separated by a permeable supporting structure, one or more access opening for the fluidic compartments, and a set of lids interchangeable with a set of insets. The permeable support structure serves as a support for the organotypic culture. The upper and lower compartments may include inlets and outlets which allow fluids to be perfused into the lower compartment and fluids to be perfused into the upper compartment. The access opening may be closed with a lid or accommodate an inset.
    Type: Application
    Filed: August 10, 2017
    Publication date: June 13, 2019
    Inventors: Paul BIGLIARDI, Zhiping WANG, Ruige WU, Massimo ALBERTI, Bo WU, Mei BIGLIARDI-QI, Sriram GOPU, Srinivas RAMASAMY, Yuri Hebert DANCIK